A5043849638- Neonatal Respiratory Health Research
- Respiratory viral infections research
- Influenza Virus Research Studies
- COVID-19 Clinical Research Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Liver Disease Diagnosis and Treatment
- Extracellular vesicles in disease
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Immune Response and Inflammation
- Immune cells in cancer
- Acute Ischemic Stroke Management
- Advanced Photocatalysis Techniques
- Optimal Power Flow Distribution
- Microgrid Control and Optimization
- Respiratory Support and Mechanisms
- Advanced battery technologies research
- Intracerebral and Subarachnoid Hemorrhage Research
- Congenital Diaphragmatic Hernia Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Fibroblast Growth Factor Research
- Cancer-related molecular mechanisms research
- Acupuncture Treatment Research Studies
- Metabolomics and Mass Spectrometry Studies
- Sepsis Diagnosis and Treatment
- Obesity, Physical Activity, Diet
Wenzhou Medical University
2019-2025
First Affiliated Hospital of Wenzhou Medical University
2019-2025
Union Hospital
2024-2025
Huazhong University of Science and Technology
2024-2025
Shandong University
2019-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
Xijing Hospital
2025
Air Force Medical University
2025
Hangzhou Medical College
2024
Zhejiang Provincial People's Hospital
2024
Pneumonia is among the most dangerous complications of infection after intracerebral hemorrhage. We aimed to create a novel nomogram for pneumonia The data from Chinese Cerebral Hemorrhage: Mechanism and Intervention (CHEERY) study was analyzed. Thirty percent qualified patients were placed in validation group (n=763) while seventy them randomly training (n=1784). In multivariate analysis, ten variables included model: age (β= 0.023, P<0.001), hospital days (β=0.392, baseline mRS score...
<b><i>Background:</i></b> Cancer-related fatigue (CRF) is one of the most troubling symptoms cancer patients during chemotherapy, and no gold standard for treatment CRF has been established. <b><i>Objective:</i></b> This study aimed to examine effects Baduanjin qigong on with colorectal CRF, explore its intervention effects. <b><i>Methods:</i></b> was an open-label, randomized controlled clinical trial. Ninety...
Background Acute respiratory infections (ARI) are the major worldwide health problem associated with high morbidity and mortality rates. Human adenovirus (HAdV) is one of most common pathogens viral ARI, thus calls for specific diagnosis better understanding epidemiology clinical characteristics. Methods Total 4,130 children ARI requiring hospitalization from 2012 to 2013 were retrospectively studied. Throat swab specimens collected each patient. Fluorescence Quantitative PCR was performed...
The epidemiological characteristics of Sjögren syndrome (SS) are significantly varied in different countries. We conducted the present study to survey primary SS China. recruited 483 patients from 16 Chinese medical centers nationwide January 2009 November 2011 and assessed salivary lacrimal gland dysfunction, organ involvement, autoimmunity these patients. cohort included 456 women 27 men (ratio, 17:1; mean age at onset, 42 ± 11 years; median diagnosis, 49 range, 41–56 years). Male showed a...
Sepsis is an aggressive and life-threatening organ dysfunction induced by infection. Excessive inflammation coagulation contribute to the negative outcomes for sepsis, resulting in high morbidity mortality. In this study, we explored whether Eupatilin could alleviate lung injury, reduce during sepsis.We constructed vitro sepsis model stimulating RAW264.7 cells with 1 μg/mL lipopolysaccharide (LPS) 6 hours. The were divided into control group, LPS LPS+ (Eup) Eup group detect their cell...
To illustrate the potential of mesenchymal stem cell-derived exosomes (MSC-Exos) in mitigating septic lung injury by reducing excessive formation neutrophil extracellular traps (NETs), a mouse model was induced through cecal ligation and puncture (CLP). The mice received intraperitoneal injections MSC-Exos. Post injection, pathological alterations tissue were evaluated HE staining, levels inflammatory markers each group at various time points assessed using ELISA kits. presence NETs...
This study aimed to assess the crucial factors that contribute self-nursing intention of discharged patients with drainage tubes, a specific emphasis on percutaneous surgeries. A case-control was conducted in accordance EQUATOR-STROBE statement. Over period January 2023 December 2023, cohort 146 tubes were recruited. Upon their return hospital for removal an anonymous questionnaire administered gather data various aspects, including basic demographic characteristics, comprehensive disease...
Backgrounds: Bronchopulmonary dysplasia (BPD) is a major contributor to mortality in extremely preterm infants. Therefore, it essential identify effective clinical prognostic indicators of BPD and implement early interventions. The objective this study was evaluate the predictive value erythrocyte-related indices, such as hemoglobin (Hb) hematocrit (Hct), for BPD. Methods: This retrospective cohort included 413 neonates with gestational age (GA) < 32 weeks who were admitted First...
To evaluate the associations between a new definition of metabolic dysfunction-associated fatty liver disease (MAFLD) and extrahepatic cancers compare with nonalcoholic (NAFLD).We enrolled 151,391 Chinese participants in Kailuan cohort. Hepatic steatosis was detected by abdominal ultrasound. Fine Gray competing risk regression models were used to estimate hazard ratios (HRs) 95% confidence interval (CI) MAFLD cancers.MAFLD associated increased prostate (HR =1.49, CI: 1.07-2.08)...
Background and Objective: Bronchopulmonary dysplasia (BPD) is a common complication in preterm infants; predicting the degree of BPD at an early life stage difficult. Inflammation crucial risk factor for pathogenesis, neutrophil-to-lymphocyte ratio (NLR) potential systemic inflammatory biomarker. We aimed to assess predictive value NLR BPD. Methods: carried out retrospective, single-center, observational study neonates with gestational ages (GAs) <32 weeks assessed association between...
Rationale: Inflammation plays a crucial role in the progression of nonalcoholic steatohepatitis (NASH). Protein tyrosine phosphatase receptor type O truncated isoform (PTPROt) is an integral membrane protein that has been identified osteoclasts, macrophages, and B lymphocytes. However, its relationship between inflammation NASH largely unknown. Herein, we aimed to study function PTPROt progression. Methods: We established mouse model wild-type (WT), PTPRO knockout mice by western diet (WD)...
Background and Objective: As bronchopulmonary dysplasia (BPD) can lead to considerable mortality morbidity, this disease is the focus of attention in neonatology. Vitamin D (VD) , which has anti-inflammatory properties promotes lung growth, may have a therapeutic effect on BPD. Neutrophil extracellular traps (NETs) overexpression were demonstrated be involved pathogenesis BPD our previous study. This study aimed elucidate VD role NETs process. Methods: Newborn rats exposed 90% oxygen...
Routine blood parameters, such as the lymphocyte (LYM) count, platelet (PLT) lymphocyte-to-monocyte ratio (LMR), neutrophil-to-lymphocyte (NLR), lymphocytes multiplied by platelets (LYM*PLT) and mean volume-to-platelet (MPV/PLT), are widely used to predict prognosis of infectious diseases. We aimed explore value these parameters in early identification influenza virus infection children.We conducted a single-center, retrospective, observational study fever with influenza-like symptoms...
Abstract Objective Bronchopulmonary dysplasia (BPD) is the most common chronic morbidity in extremely preterm infants. Mesenchymal stem cells‐derived exosomes (MSC‐Exos) therapies have shown prospects animal models of BPD. Our study aimed to evaluate effect adipose mesenchymal (AMSC‐Exos) on BPD and role NF‐κB signaling pathway this process. Methods The AMSCs were extracted AMSC‐Exos isolated by ultracentrifugation method. Newborn rats exposed hyperoxia (90% O 2 ) continuously for 7 days...
Intracerebral hemorrhage (ICH) is the cerebrovascular disease with highest disability and mortality rates, causing severe damage to health of patients imposing a significant socioeconomic burden. Aging stands as foremost risk factor for ICH, escalation in ICH incidence within elderly demographic, highlighting close association between aging. In recent years, acceleration “aging society” trend, exploring intricate relationship aging has become increasingly urgent worthy in-depth attention. We...