A5101784800- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Lung Cancer Treatments and Mutations
- Neuroendocrine Tumor Research Advances
- Gastrointestinal disorders and treatments
- Metastasis and carcinoma case studies
- Lung Cancer Research Studies
- Medical Research and Treatments
- Gastroesophageal reflux and treatments
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Colorectal Cancer Treatments and Studies
- Cardiovascular Health and Risk Factors
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Eosinophilic Esophagitis
- Synthesis and biological activity
- Computational Drug Discovery Methods
- Obesity, Physical Activity, Diet
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Gastrointestinal Tumor Research and Treatment
- Cancer-related molecular mechanisms research
- Nitric Oxide and Endothelin Effects
- Lung Cancer Diagnosis and Treatment
- Cancer Cells and Metastasis
East China Normal University
2025
Shanghai Changning Mental Health Center
2025
Qingdao Municipal Hospital
2015-2024
Qingdao University
2015-2024
Harbin Medical University
2024
Second Affiliated Hospital of Harbin Medical University
2024
People's Liberation Army 401 Hospital
2023
Kunming Medical University
2015-2022
117th Hospital of People's Liberation Army
2022
Beijing Tsinghua Chang Gung Hospital
2021
Helicobacter pylori infection is mostly a family-based infectious disease. To facilitate its prevention and management, national consensus meeting was held to review current evidence propose strategies for population-wide H. control management reduce the related disease burden.Fifty-seven experts from 41 major universities institutions in 20 provinces/regions of mainland China were invited modify statements using Delphi process grading recommendations assessment, development evaluation...
OBJECTIVE The incidence of high dietary carbohydrate-induced type 2 diabetes is increasing worldwide. Methylglyoxal (MG) a reactive glucose metabolite and major precursor advanced glycation end products (AGEs). MG levels are elevated in diabetic patients. We investigated the effects chronic administration on tolerance β-cell insulin secreting mechanism 12-week-old male Sprague-Dawley rats. RESEARCH DESIGN AND METHODS (60 mg/kg/day) or 0.9% saline was administered by continuous infusion with...
Expression of atheroprotective genes in the blood vessel wall is potentially an effective means preventing or reversing atherosclerosis. Development this approach has been hampered by lack a suitable gene-transfer vector. We used helper-dependent adenoviral (HDAd) vector to test whether expression apolipoprotein A-I (apoA-I) artery could retard development atherosclerosis hyperlipidemic rabbits. Carotid arteries were infused with HDAd expressing rabbit apoA-I "null" and harvested 2 4 weeks...
The aim of this study was to compare chromoendoscopy (CE), narrow band imaging (NBI), and confocal laser endomicroscopy (CLE) in diagnosing atrophic gastritis.Atrophic gastritis, especially metaplastic atrophy, has been shown be a risk factor for gastric cancer. Some advanced endoscopic techniques have used diagnose gastritis. However, it is still difficult atrophy with high degree accuracy.In total, 253 sites from 87 consecutive patients were examined by NBI, CE, CLE, turn diagnoses made....
Objective: The aim of this study was to investigate the correlation between efficacy epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) and circulating tumor cell (CTC) levels in patients with advanced non-small lung cancer (NSCLC). EGFR-TKIs reducing CTC counts NSCLC studied. Patients methods: A total 66 were enrolled divided into two groups (those high those low counts) based on patients' median counts. All treated an EGFR-TKI, treatment prognoses compared. Results:...
Objective To explore the early onset, development and histological features of gastric signet-ring cell carcinoma (SRCC). Methods Three hundred sixty-two patients with differentiated adenocarcinoma cells were enrolled. Histomorphological immunohistochemical patterns specimens observed in detail. Results Infection mucosa, especially by Helicobacter pylori , can cause massive proliferation transformation deep foveola, isthmus gland, proliferative zone upper neck gland. Signet-ring-like...
A case-control study among Singapore Armed Forces' newly enlisted Servicemen was conducted to examine factors associated with male obesity. Four hundred and fifty-nine individuals from the Obese Basic Military Training program were selected as "cases" (average age: 19.5, body mass index: 30.4) another 340 Normal "controls" 19.3, 21.4). Information such family background, socioeconomic factors, lifestyle practices captured using facilitator-led questionnaires. Several variables significantly...
To investigate risk factors for extrahepatic cholangiocarcinoma (ECC) in China. A total of 200 ECC cases and matched control were included the study. The presence cigarette smoking, alcohol drinking, choledocholithiasis, primary sclerosing cholangitis, liver fluke infection ( Clonorchis sinensis ), diabetes mellitus, was investigated through clinical records. Blood from all tested hepatitis B surface antigen. Odds ratios (OR) 95% confidence intervals (CIs) estimated using conditional...
Exogenous lipoid pneumonia is a rare entity, the diagnosis often missed or delayed. To investigate clinical characteristics of exogenous lipid in elderly patients, improve efficiency early and treatment this disease. Retrospectively analyzed information imaging data these 2 reviewed related literature. Both patients were over 60 with history gastrointestinal diseases. The presentation nonspecific. Chest CT showed many different manifestations. Histopathology analysis revealed accumulation...
To systematically determine the miss rate and risk factors for polyps, adenomas advanced in same population, to further analyze impact of colonoscopy with anesthesia on rate.We retrospectively analyzed information patients undergoing second within 1 year after their first. The patient lesion were calculated. features missed compared non-missed lesion. Finally, divided into group without group, lesions was analyzed.The 32.8, 25.6 10.4%, 19.6, 15.8 7.2%. In multivariable logistic regression...
We aimed to investigate the immunophenotype, differential diagnosis, and clinicopathological characteristics of signet-ring cell carcinoma (SRCC) derived from gastric foveolar epithelium.Clinical characteristics, endoscopic findings, histopathological features, follow-up data seven cases SRCC epithelium with small intramucosal lesions were analyzed.Seven patients a mean age 38.3 years diagnosed lesions, all them negative for CDH-1 germline mutation. The glands proliferated expanded, then...