Zheng Cao

ORCID: 0000-0003-2018-1569
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Research Areas
  • Advanced Sensor and Energy Harvesting Materials
  • Hydrogels: synthesis, properties, applications
  • Electrospun Nanofibers in Biomedical Applications
  • Nerve injury and regeneration
  • Laser Material Processing Techniques
  • Advanced ceramic materials synthesis
  • Surface Modification and Superhydrophobicity
  • Polymer Surface Interaction Studies
  • biodegradable polymer synthesis and properties
  • Analytical Chemistry and Sensors
  • Adsorption and biosorption for pollutant removal
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Polymer Nanocomposites and Properties
  • Bone Tissue Engineering Materials
  • Spinal Cord Injury Research
  • Advanced Polymer Synthesis and Characterization
  • Aquaculture disease management and microbiota
  • Nanocluster Synthesis and Applications
  • Polymer crystallization and properties
  • Additive Manufacturing and 3D Printing Technologies
  • Conducting polymers and applications
  • Advanced Nanomaterials in Catalysis
  • Cultural Heritage Materials Analysis
  • Carbon Nanotubes in Composites
  • Electrohydrodynamics and Fluid Dynamics

Changzhou University
2015-2025

Jiangsu University
2024-2025

Army Medical University
2025

Xinqiao Hospital
2025

Jingdezhen University
2025

Tsinghua University
2017-2024

State Key Laboratory of New Ceramics and Fine Processing
2017-2024

Anhui Medical University
2024

Chinese Academy of Sciences
2019-2023

Institute of Biophysics
2021-2023

No Genetic Vertigo Peoples living in high altitudes have adapted to their situation (see the Perspective by Storz ). To identify gene regions that might contributed high-altitude adaptation Tibetans, Simonson et al. (p. 72 , published online 13 May) conducted a genome scan of nucleotide polymorphism comparing Han Chinese, and Japanese, while Yi 75 ) performed comparable analyses on coding all genes—their exomes. Both studies converged gene, endothelial Per-Arnt-Sim domain protein 1 (also...

10.1126/science.1190371 article EN Science 2010-07-01

Autologous nerve transplantation, which is the gold standard for clinical treatment of peripheral injury, still has many limitations.In this study, aligned chitosan fiber hydrogel (ACG) grafted with a bioactive peptide mixture consisting RGI (Ac-RGIDKRHWNSQGG) and KLT (Ac-KLTWQELYQLKYKGIGG), designated as ACG-RGI/KLT, was used conduit filler to repair sciatic defects in rats.Methods: Chitosan nanofiber prepared by combination electrospinning mechanical stretching methods, then KLT, are...

10.7150/thno.36272 article EN cc-by Theranostics 2020-01-01

Rehabilitation and regenerative medicine are two promising approaches for spinal cord injury (SCI) recovery, but their combination has been limited. Conductive biomaterials could bridge scaffolds with electrical stimulation by inducing axon regeneration supporting physiological signal transmission. Here, we developed aligned conductive hydrogel fibers incorporating carbon nanotubes (CNTs) into methacrylate acylated gelatin (GelMA) via rotating liquid bath electrospinning. The electrospun...

10.1016/j.bioactmat.2024.01.021 article EN cc-by-nc-nd Bioactive Materials 2024-02-22

Background: Designing novel biomaterials that incorporate or mimic the functions of extracellular matrix to deliver precise regulatory signals for tissue regeneration is focus current intensive research efforts in engineering and regenerative medicine. Methods results: To natural environment spinal cord tissue, a three-dimensional hierarchically aligned fibrin hydrogel (AFG) with oriented topography soft stiffness has been fabricated by electrospinning concurrent molecular self-assembling...

10.2147/ijn.s159356 article EN cc-by-nc International Journal of Nanomedicine 2018-05-01

Nerve guidance conduits (NGCs) have been widely accepted as a promising strategy for peripheral nerve regeneration. Fabricating ideal NGCs with good biocompatibility, biodegradability, permeability, appropriate mechanical properties (space maintenance, suturing performance, etc.), and oriented topographic cues is still current research focus. From the perspective of translation, technique stability scalability are also an important consideration industrial production. Recently, blow-spinning...

10.1016/j.mtbio.2024.100942 article EN cc-by-nc-nd Materials Today Bio 2024-01-04

A simplified approach to increase neuronal attachment on an agarose hydrogel was proposed by blending with another biocompatible polysaccharide, chitosan. The stiffness of the gel maintained despite inclusion chitosan, as determined rheological tests. structure blended hydrogels characterized using light microscopy and scanning electron microscopy. An in vitro cell study revealed that blends promoted neuron adhesion. concentration chitosan had great influence morphology neurons. optimum...

10.1021/bm900670n article EN Biomacromolecules 2009-09-15

Using bismuth oxide (Bi2O3) as a laser-marking additive and thermoplastic polyurethane (TPU) the matrix, TPU/Bi2O3 composite materials were prepared by melt blending in torque rheometer. The sheet samples from composites treated air scanning with neodymium-doped yttrium aluminum garnet (Nd: YAG) pulsed laser beam at wavelength of 1064 nm. Compared pure TPU sample, laser-marked exhibited differences marking contrast Bi2O3 content increased 0.1% to 1.0% based on stereomicroscope analysis....

10.1021/acsami.5b07406 article EN ACS Applied Materials & Interfaces 2015-10-15

Mesenchymal stem cell (MSC)-based regenerative medicine is widely considered as a promising approach for repairing tissue and re-establishing function in spinal cord injury (SCI). However, low survival rate, uncontrollable migration, differentiation of cells after implantation represent major challenges toward the clinical deployment this approach. In study, we fabricated three-dimensional MSC-laden microfibers via electrospinning rotating culture to mimic nerve tissue, control behavior,...

10.1021/acsbiomaterials.9b01557 article EN ACS Biomaterials Science & Engineering 2020-01-22

Hollow silica nanospheres with mesoporous shells were successfully fabricated a new one-pot strategy by using thermosensitive polymer, poly(N-isopropylacrylamide) (PNIPAm), as reversible template without the need of further calcination or chemical etching. By simply regulating solution temperature respect to lower critical (LCST) PNIPAm, PNIPAm chains can reversibly form aggregates dissolve in aqueous solution. The character makes behave soft templates for formation core-shell at elevated...

10.1021/la902531p article EN Langmuir 2009-09-18

ABSTRACT The present work aimed to develop polyvinyl alcohol (PVA) hydrogel films with physically crosslinking through controllable entanglement density of the polymer chains. viscoelasticity PVA aqueous solutions was investigated over a broad range in molecular weight. chain length between crosslinks () and determined by plateau modulus ( G' ). value increased weight, which can be attributed enhanced associated hydrogen bonds inter‐ interchains. melting crystallization transparent showed...

10.1002/polb.24902 article EN Journal of Polymer Science Part B Polymer Physics 2019-11-29

In this work, poly(ethylene terephthalate) (PET) chain-extending products with different molecular weights were prepared by reactive extrusion using isocyanate trimer (C-HK) as the trifunctional chain extender. The effect of extender C-HK on intrinsic viscosity, melt flow property, crystallization behavior, morphology, and mechanical property PET was investigated. results showed that when content increased from 0.6 to 1.4 wt%, viscosity average weight effectively 2.36 × 104 5.46 g·mol-1....

10.1021/acsomega.0c02815 article EN publisher-specific-oa ACS Omega 2020-07-24

10.1016/j.jmst.2021.06.043 article EN Journal of Material Science and Technology 2021-08-27

Abstract Using chemically etched stainless steel mesh (SSM) as matrix, chitosan (CS) the hydrophilic component and acrylamide (AAm) monomer, underwater superoleophobic membrane (PAAm/CS@SSM) for oil–water separation was prepared by free radical polymerization initiated ultraviolet light. The composition, morphology, oil contact angle, structure of PAAm/CS@SSM were characterized Fourier‐transform infrared spectroscopy, x‐ray powder diffraction, scanning electron microscopy, confocal laser...

10.1002/pol.20210923 article EN Journal of Polymer Science 2022-02-21

Dye pollution has long been an ecological and human health issue. Activated carbon is considered to be the most promising material for dye adsorption. In this study, bamboo was used as a biomass precursor produce activated with high specific surface area by steam activation method. The physical reaction between water vapor promotes carbonization product have rich porous structure. prepared investigated from perspectives of morphology, elemental change, porosity, functional groups using...

10.1021/acs.langmuir.3c01972 article EN Langmuir 2023-09-19
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