Valentin Kolev

ORCID: 0000-0003-2034-5180
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About
Contact & Profiles
Research Areas
  • Endometrial and Cervical Cancer Treatments
  • Ovarian cancer diagnosis and treatment
  • Uterine Myomas and Treatments
  • Endometriosis Research and Treatment
  • COVID-19 and healthcare impacts
  • Cervical Cancer and HPV Research
  • BRCA gene mutations in cancer
  • Intraperitoneal and Appendiceal Malignancies
  • Colorectal and Anal Carcinomas
  • Global Cancer Incidence and Screening
  • Neuroendocrine Tumor Research Advances
  • Gynecological conditions and treatments
  • Lung Cancer Research Studies
  • Sarcoma Diagnosis and Treatment
  • Economic and Financial Impacts of Cancer
  • Gestational Trophoblastic Disease Studies
  • Microgrid Control and Optimization
  • Cancer survivorship and care
  • Circular RNAs in diseases
  • Radiomics and Machine Learning in Medical Imaging
  • Brain Metastases and Treatment
  • Maternal and fetal healthcare
  • Maternal and Perinatal Health Interventions
  • Minimally Invasive Surgical Techniques
  • Cancer Immunotherapy and Biomarkers

Icahn School of Medicine at Mount Sinai
2015-2024

Mount Sinai Hospital
2010-2024

The Mount
2023

Mount Sinai Hospital
2021-2022

Mount Sinai Beth Israel
2013-2021

Technical University of Sofia
2021

Institute for Nuclear Research and Nuclear Energy
2021

Mount Sinai Hospital
2019-2021

Mount Sinai Medical Center
2012-2014

Memorial Sloan Kettering Cancer Center
2009-2010

Ovarian cancer is a leading cause of deaths among women. Effective targets to treat advanced epithelial ovarian (EOC) and biomarkers predict treatment response are still lacking because the complexity pathways involved in progression. Here we show that miR-181a promotes TGF-β-mediated epithelial-to-mesenchymal transition via repression its functional target, Smad7. phosphorylated Smad2 enriched recurrent compared with matched-primary tumours their expression associated shorter time...

10.1038/ncomms3977 article EN cc-by-nc-nd Nature Communications 2014-01-07

BackgroundThe coronavirus disease 2019 pandemic has resulted in unprecedented challenges for the oncology community. For people living with cancer, treatments are interrupted, surgeries cancelled, and regular evaluations rescheduled. People cancer their physicians must balance plausible fears of treatment consequences delaying care.ObjectiveWe aim to evaluate experience women ovarian during pandemic.Study DesignWomen a current or previous diagnosis completed an online survey focusing on...

10.1016/j.ajog.2020.06.049 article EN other-oa American Journal of Obstetrics and Gynecology 2020-06-26

Introduction: It has been hypothesized that the supradiaphragmatic lymph nodes serve as principal for lymphatic drainage of entire peritoneal cavity. The purpose this study was to determine prognostic significance enlarged noted on preoperative computed tomographic (CT) scan in patients undergoing primary cytoreduction advanced epithelial ovarian cancer (EOC). Methods: We performed a retrospective chart review all with stage III and IV EOC according International Federation Gynecology...

10.1111/igc.0b013e3181e833f5 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2010-07-01

The aim of this study is to determine the role liver metastatectomy in morbidity and survival patients with recurrent ovarian carcinoma.We retrospectively reviewed records all who had undergone hepatic resection for metastases from carcinoma at time cytoreductive surgery our institution 1988 2012. Kaplan-Meier method was used analysis. A total 76 met inclusion criteria as part during period. Of these patients, 27 underwent secondary cytoreduction, that are focus analysis.Median overall group...

10.1097/igc.0000000000000026 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2013-12-19

Endometrial cancer is the most common gynecologic malignancy in industrialized countries, and both its incidence associated mortality are increasing. The “liquid biopsy” becoming an important transformative precision oncology tool, but barriers intrinsic to blood sampling have limited use early detection. We hypothesized that using a more targeted sample for analysis—namely, uterine lavage—should provide sensitive specific diagnostic test endometrial cancer. Using custom 12-gene panel,...

10.1101/mcs.a003269 article EN Molecular Case Studies 2018-10-09

► 33 years old woman diagnosed with choriocarcinoma after delivery, her newborn son the same diagnosis. Case of transplasental dissemination choriacarcinoma. Advanced disease both in mother and infant.

10.1016/j.gynor.2012.05.002 article EN cc-by-nc-nd Gynecologic Oncology Case Reports 2012-05-09

Our aim was to assess current surgical practices and use of adjuvant therapy in the treatment FIGO (International Federation Gynecology Obstetrics) stage I endometrioid endometrial cancer.A 19-question survey developed sent all Society Gynecologic Oncologist members by e-mail. Data were collected anonymously using Internet-based software. Respondents asked questions regarding preoperative evaluation, approach, lymph node dissection (LND), therapy.A total 1399 surveys distributed, 320 (23%)...

10.1097/igc.0000000000000589 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2015-11-14

Constitutional trisomy 8 mosaicism (CT8M) in liveborns is typically caused by mitotic non-disjunction and exhibits wide phenotypic variability. By contrast, CT8M due to meiotic errors usually results miscarriage. We describe a case of paternal meiosis II error. The patient, 32-year-old woman, was phenotypically normal except for history recurrent aphthous ulcers since childhood 4-year macrocytosis. were refractory steroids, but responded well thalidomide. To the best our knowledge, this...

10.1002/ajmg.a.20390 article EN American Journal of Medical Genetics Part A 2003-12-01

Mounting evidence suggests disproportionate coronavirus disease 2019 (COVID-19) hospitalizations and deaths because of racial disparities. The association race in a cohort gynecologic oncology patients with severe acute respiratory syndrome-coronavirus 2 infection is unknown. Data were abstracted from COVID-19 among 8 New York City area hospital systems. A multivariable mixed-effects logistic regression model accounting for county clustering was used to analyze COVID-19-related...

10.1002/cncr.33335 article EN Cancer 2020-12-09

The aim of this paper is to present a case cesarean section ectopic pregnancy (CSP) diagnosed in the second trimester and perform literature review current guidelines for management CSP trimester. This was exempt from Mount Sinai IRB. 35-year-old P1122 at 13w4d who presented our hospital with vaginal spotting abdominal pain. patient found have placenta increta. There are no CSP, published material minimal. A completed demonstrated two cases one series on existing CSP. Our underwent an...

10.1155/2021/8888019 article EN cc-by Case Reports in Obstetrics and Gynecology 2021-02-09

Previvors are becoming more aware of the option risk-reducing salpingectomy with delayed oophorectomy (RRS-DO) to mitigate their risk ovarian cancer. In this qualitative study, we explored clinical and non-clinical factors that impacted previvors' decision-making pursue RRS-DO as a reduction strategy.Semi-structured telephone interviews were conducted previvors transcribed verbatim. Using ATLAS.ti® software, two primary investigators interpreted data through thematic analysis. After coding...

10.1016/j.gore.2022.100948 article EN cc-by-nc-nd Gynecologic Oncology Reports 2022-02-26

A carcinoid tumor occurring in the endometrium has been documented literature, but there is no report regard to metastasis endometrium.

10.1016/j.ijscr.2012.10.007 article EN International Journal of Surgery Case Reports 2012-10-17
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