A5100661707- Cancer-related molecular mechanisms research
- Reproductive System and Pregnancy
- MicroRNA in disease regulation
- Immune Response and Inflammation
- Extracellular vesicles in disease
- RNA Research and Splicing
- Genetic and phenotypic traits in livestock
- Reproductive Physiology in Livestock
- Endometriosis Research and Treatment
- Cancer Genomics and Diagnostics
- Spectroscopy and Chemometric Analyses
- Galectins and Cancer Biology
- Insect Resistance and Genetics
- Bacillus and Francisella bacterial research
- Circular RNAs in diseases
- Insect and Pesticide Research
- Meat and Animal Product Quality
- Currency Recognition and Detection
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Vagus Nerve Stimulation Research
- Cardiac Fibrosis and Remodeling
- Lipid metabolism and disorders
- Liver Disease Diagnosis and Treatment
- Sperm and Testicular Function
- Neuropeptides and Animal Physiology
Jilin University
2024
Ministry of Agriculture and Rural Affairs
2023
Henan Agricultural University
2017-2023
Zhejiang University
2022-2023
Huaian First People’s Hospital
2022-2023
Harbin Medical University
2021-2022
First Affiliated Hospital of Harbin Medical University
2021-2022
State Key Laboratory of Modern Optical Instruments
2022
Tianjin Medical University
2022
Second Hospital of Tianjin Medical University
2022
Abstract Establishment of implantation in pig is accompanied by a coordinated interaction between the maternal uterine endometrium and conceptus development. We investigated expression profiles endometrial tissue on Days 9, 12 15 pregnancy Day non-pregnancy Yorkshire performed comprehensive analysis long non-coding RNAs (lncRNAs) samples using RNA sequencing. As result, 2805 novel lncRNAs, 2,376 (301 lncRNA 2075 mRNA) differentially expressed genes (DEGs) 2149 transcripts were obtained...
Understanding the genetic basis of host shifts is a key genomic question for pathogen and parasite biology. The Bacillus cereus group, which encompasses thuringiensis anthracis, contains pathogens that can infect insects, nematodes, vertebrates. Since target range essential virulence factors (Cry toxins) many isolates well known, this group presents powerful system investigating how diversify adapt to phylogenetically distant hosts. Specialization exploit insects occurs at level major clade...
Quantum digital signatures (QDS), based on the principles of quantum mechanics, provide information-theoretic security, ensuring integrity, authenticity, and non-repudiation data transmission. With present QDS protocols, measurement-device-independent (MDI-QDS) can resist all attacks detections, yet it suffers from finite-size effect. In this work, we compare three parameter estimation models for analysis two-decoy MDI-QDS. The first model is a commonly used in previous schemes, propose two...
β-cryptoxanthin (CRY), a major carotenoid of potential interest for health, is obtained naturally from orange vegetables and fruits. A few research studies have reported that CRY could decrease oxidative stress germ cell apoptosis. The purpose this study was to examine the effects on acute cadmium chloride (CdCl2)-induced damage in rat testes. For study, 24 rats were divided into four groups, one which serves as control group received intraperitoneal (i.p.) injections corn oil physiological...
<i>Background:</i> The isoflavone puerarin is the most abundant isoflavone-C-glucoside extracted from root (radix puerariae) of plant <i>Pueraria lobata</i> and possesses many biological activities. In this report, ability to modulate intercellular adhesion molecule 1 (ICAM-1), vascular cell (VCAM-1) endothelial leukocyte (E-selectin), induce changes in nuclear factor ĸB (NF-ĸB) pathway human umbilical vein cells (HUVECs) was examined. <i>Methods:</i>...
Despite the successful application of crystal proteins (Cry) from Bacillus thuringiensis as biological control agents against insects, there is an increasing demand to identify new Cry toxins having higher toxicity and broad-spectrum activity insects plant-parasitic nematodes. To find novel toxins, we screened 100 whole-genome sequences B. Surprisingly, in addition full found partial sequences, such typical N-terminal or C-terminal regions with conserved domains, widely distributed among 20...
Endometrial receptivity plays a vital role in successful embryo implantation pigs. MicroRNAs (miRNAs), known as regulators of gene expression, have been implicated the regulation implantation. However, miRNAs endometrial during pre-implantation period remains elusive. In this study, we report that expression level Sus scrofa (ssc)-miR-21-5p porcine endometrium tissues was significantly increased from day 9 to 12 pregnancy. Knockdown ssc-miR-21-5p inhibited proliferation and migration...
Abstract The proliferation and differentiation of granulosa cells (GCs) is a crucial process in follicular development. However, the molecular regulatory mechanism GCs needs further research. Studies have reported that fluid exosomes are involved regulation GCs, but specific unclear. This study demonstrated LOC102163816 upregulated porcine treated with exosomes. Further defined to be novel long noncoding RNA highly homologous human metastasis-associated lung adenocarcinoma transcript 1...
Embryonic implantation involves a complex and well‐coordinated interaction between the developing conceptus maternal uterus, preimplantation period has major impact on litter size in pigs. The present study aimed to investigate vital messenger RNAs (mRNAs) long noncoding (lncRNAs) that regulate Meishan enriched Gene Ontology terms were all related “binding.” Furthermore, “ECM‐receptor interaction” was predicted as an important pathway regulated success of implantation. We speculated...
// Pei-Ge Chen 1, * , Yan-Jing Guan Guang-Ming Zha Xian-Qin Jiao 1 He-Shui Zhu Cheng-Yu Zhang Yue-Ying Wang and He-Ping Li Key Laboratory of Animal Biochemistry Nutrition, Ministry Agriculture, Henan Agricultural University, Zhengzhou, Henan, China These authors have contributed equally to this work Correspondence to: Li, email: liheping1972@126.com Wang, wangyueying2008@126.com Keywords: IRF3/IRF7, inflammatory response, overexpression, TLR4 signaling pathway, lipopolysaccharide Received:...
Acute myeloid leukemia (AML) is a type of cancer that consists group hematological malignancies with high heterogeneity. DNA methyltransferase 3A (DNMT3A)-mutated AML patients have poor prognosis. Some long non-coding RNAs (lncRNAs) been reported to enhance therapeutic sensitivity, and so could affect the overall survival rate elderly cytogenetically normal acute (CN-AML) patients; however, studies on lncRNA signature in DNMT3A-mutated are rare.The DNMT3A R878H conditional knock-in mouse...
Abstract MicroRNA‐543 (miR‐543) has been found to play a suppressive role in various human cancers many studies, whereas the specific functions of miR‐543 muscle development remain poorly understood. Here, we that expression was high skeletal and increased during differentiation C2C12 cells. Overexpression repressed cell proliferation promoted differentiation, while knockdown produced opposite results. During myogenesis, predicted verified Krüppel‐like factor 6 ( KLF6 ), suppressor multiple...
Abstract Background Endometrial receptivity plays a vital role in the success of embryo implantation. However, temporal proteomic profile porcine endometrium during implantation is still unclear. Results In this study, abundance proteins on days 9, 10, 11, 12, 13, 14, 15 and 18 pregnancy (D9, 18) was profiled via iTRAQ technology. The results showed that 25, 55, 103, 91, 100, 120, 149 were up-regulated, 24, 70, 169, 159, 164, 161, 198 down-regulated D10, compared with D9, respectively. Among...