- Public-Private Partnership Projects
- Cardiac Valve Diseases and Treatments
- Veterinary medicine and infectious diseases
- Statistical Methods in Clinical Trials
- Viral gastroenteritis research and epidemiology
- Hepatitis Viruses Studies and Epidemiology
- Lung Cancer Research Studies
- Infective Endocarditis Diagnosis and Management
- Advanced MRI Techniques and Applications
- Cardiac Structural Anomalies and Repair
- Lung Cancer Treatments and Mutations
- Climate Change and Health Impacts
- Cardiac Imaging and Diagnostics
- Cardiac pacing and defibrillation studies
- Heart Rate Variability and Autonomic Control
- Renal cell carcinoma treatment
- Animal Virus Infections Studies
- Influenza Virus Research Studies
- EEG and Brain-Computer Interfaces
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Diet and metabolism studies
- Renal and related cancers
- Air Quality and Health Impacts
- Biosimilars and Bioanalytical Methods
Fraunhofer Institute for Photonic Microsystems
2023
Ernst Abbe University of Applied Sciences Jena
2016-2022
Carl Zeiss (Germany)
2021
Jena University Hospital
2011-2020
Berlin Heart (Germany)
2017
Friedrich Schiller University Jena
2008-2016
Schiller International University
2011-2014
Stanford University
2012
Palo Alto Institute
2012
National Institutes of Health
2005
Most epileptic seizures occur unexpectedly and independently of known risk factors. We aimed to evaluate the clinical significance patients' perception that weather is a factor for seizures.Using hospital-based, bidirectional case-crossover study, 604 adult patients admitted large university hospital in Central Germany an unprovoked seizure between 2003 2010 were recruited. The effect atmospheric pressure, relative air humidity, ambient temperature on onset under temperate climate conditions...
Aims High concentrations of air pollutants are associated with increased risk for myocardial infarction. The European Union has defined statutory limits based on upper absolute concentrations. We evaluated the association between rapid changes in and infarction independently Methods results Using a hospital-based case-crossover study, effects 24h nitrogen oxides (NOX/2), particulate matter (PM10), ozone was assessed 693 patients. In overall population, increases NOX more than 20 µg/m3 within...
Picornaviruses have been isolated from a variety of hosts, mainly mammals and birds. Here, we describe the sequence analysis carp picornavirus 1 (CPV-1) F37/06 that was an organ pool (heart, brain, liver) common (Cyprinus carpio). This perished after accidental discharge liquid manure into fish pond presented without obvious clinical symptoms. Experimental intraperitoneal infection young with CPV-1 revealed no signs, but virus re-isolated various organs. Sequence almost complete genome (7632...
We hypothesized that annuloplasty ring implantation alters mitral annular strains in a normal beating ovine heart preparation.Sheep had 16 radiopaque markers sewn equally spaced around the annulus. Edwards Cosgrove partial flexible band (COS; n=12), St Jude complete rigid saddle-shaped (RSA; n=10), Carpentier-Edwards Physio (PHY; n=11), IMR ETlogix (ETL; and GeoForm (GEO; n=12) rings were implanted releasable fashion. Four-dimensional marker coordinates obtained using biplane...
Time-variant partial directed coherence (tvPDC) is used for the first time in a multivariate analysis of heart rate variability (HRV), respiratory movements (RMs) and (systolic) arterial blood pressure. It shown that respiration-related HRV components which also occur at other frequencies besides RM frequency (= sinus arrhythmia, RSA) can be identified. These additional are known to an effect 'half-the-mean-heart-rate-dilemma' ('cardiac aliasing' CA). CA may contaminate entire range lead...
Exercise‐induced changes of transverse proton relaxation time ( T 2 ), tissue perfusion and metabolic turnover were investigated in the lower back muscles volunteers by applying muscle functional MRI (mfMRI) diffusion‐weighted imaging (DWI) before after as well dynamic 31 P‐MRS during exercise. Inner M. multifidus , MF) outer erector spinae ES) examined 14 healthy young men performing a sustained isometric trunk‐extension. Significant phosphocreatine (PCr) depletions ranging from 30% (ES) to...
<b><i>Background:</i></b> To evaluate if weather or changes in are risk factors for Bell’s palsy (BP) as exposure to draught of cold air has been popularly associated with the occurrence BP. <b><i>Methods:</i></b> Using a multicenter hospital-based case-crossover study, we analyzed association between ambient temperature, atmospheric pressure, relative humidity their 24 h and BP 825 patients subgroups....
Abstract Simvastatin, a cholesterol‐lowering drug, is reported to have immunomodulatory properties that attenuated acute lung injury independent of their major lipid lowering effects. Based on these reports, simvastatin expected be used for influenza prophylaxis and treatment. The present study evaluated the efficacy against A/PR/8/34 virus infection in murine model. In first study, was administered orally. To achieve high plasma levels, intraperitoneal application second study. Survival,...