- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Plant Pathogens and Fungal Diseases
- Plant Pathogenic Bacteria Studies
- Plant Virus Research Studies
- Plant and Fungal Interactions Research
- Plant Physiology and Cultivation Studies
- Hepatitis Viruses Studies and Epidemiology
- Plant Disease Resistance and Genetics
- Plant pathogens and resistance mechanisms
- Plant Reproductive Biology
- Plant tissue culture and regeneration
- Fungal Plant Pathogen Control
- Plant Pathogens and Resistance
- Animal Virus Infections Studies
- Plant and animal studies
- Diabetes and associated disorders
- Liver Disease and Transplantation
- Insect-Plant Interactions and Control
- Drug-Induced Hepatotoxicity and Protection
- HIV/AIDS drug development and treatment
- Viral gastroenteritis research and epidemiology
- Plant-Microbe Interactions and Immunity
- Cytomegalovirus and herpesvirus research
Plant & Food Research
2013-2024
Australian National University
2022
King's College Hospital
2008-2020
University of the South Pacific - Samoa Campus
2016
Hawke's Bay Regional Council
2016
Institute of Medical Microbiology and Hygiene
2014
King's College London
2013-2014
Heinrich Heine University Düsseldorf
2013
Hôpital Mustapha Pacha
2013
King's College School
2013
On the basis of historical studies, hepatitis delta virus (HDV) infection is considered uncommon in United Kingdom (UK) and mainly confined to intravenous drug users. In order assess current prevalence HDV co-infection patients with chronic B (HBV), a retrospective analysis was performed 962 consecutive HBV-infected adult referred King's College Hospital between January 1st 2000 March 31st 2006. The 82 subjects positive for antibody (8.5%) had similar age those without (median 36 years,...
Breeding of fire blight resistant scions and rootstocks is a goal several international apple breeding programs, as options are limited for management this destructive disease caused by the bacterial pathogen Erwinia amylovora. A broad, large-effect quantitative trait locus (QTL) resistance has been reported on linkage group 3 Malus 'Robusta 5'. In study we identified markers derived from putative genes associated with QTL integrating further genetic mapping studies bioinformatics analysis...
Pollen dimorphism during the ripening of Nicotiana tabacum anthers takes form differentiation at binucleate pollen stage into normal (N) grains, characterized by their high frequency, larger size, densely–staining cytoplasm and starch content smaller (S) grains variable low frequency weakly–staining cytoplasm. Most S show distinctive vegetative generative nuclei (A grains); a small number have two vegetative–type (B grains). Evidence is presented that when excised are cultured, plants arise...
Anthers of Nicotiana tabacum produce ethylene when cultured for plantlet production. The rate is at a maximum 1–2 weeks after the onset culture. Charcoal in medium increases proportion androgenic anthers N. and several other species. level culture vessels reduced by charcoal. However, complete removal does not significantly alter incidence androgenesis, nor continuous flushing cultures with air. It concluded that although charcoal reduces gas phase its effect on androgenesis exerted through...
ObjectivesAntimicrobial resistance of Helicobacter pylori endangers the successful eradication bacteria. The aim this prospective surveillance study (ResiNet) is to continuously keep antimicrobial H. in Germany under and identify risk factors for its development.
Although the most common path of infection for fire blight, a severe bacterial disease on apple, is via host plant flowers, quantitative trait loci (QTLs) blight resistance to date have exclusively been mapped following shoot inoculation. It not known whether same mechanism underlies flower and resistance.We report detection QTL independent artificial inoculation flowers shoots two F1 segregating populations derived from crossing resistant Malus ×robusta 5 (Mr5) with susceptible 'Idared'...
In 2012 trials were established in four kauri forest sites severely affected by dieback (Phytophthora agathidicida P taxon Agathis PTA) to determine the potential of phosphorous acid (phosphite) as a control tool Baseline assessments 162 trial trees included canopy disease rating trunk lesion dimensions and activity (recent bleeding/ 20cm intervals around Control left untreated After 1 year half previously injected reinjected all cases with 75 phosphite Phytotoxicity symptoms (leaf yellowing...
This collaborative work by over 180 researchers from 40+ countries addresses the challenges posed “phantom agents”—putative pathogenic agents named in literature without supporting data on their existence. Those remain regulatory lists, creating barriers trade and plant certification. Historically identified based solely symptoms, these lack isolates or sequence data, making reliable detection risk assessment impossible. After reviewing 120 such across 10 key genera, we recommend removal...
The effect of HIV-related immunosuppression and antiretroviral therapy on the reactivation latent hepatitis B virus (HBV) infection is unclear. We report four patients with advanced abnormal liver function tests who had evidence HBV reactivation. Reclearance occurred in two cases HIV treatment regimens not containing lamivudine, suggesting that improved immune may be responsible. In three cases, was recognized during investigation for initially attributed to drug toxicity. possibility must...
Abstract Pollen is traded internationally as a source of germplasm and for pollination. Thirty‐nine viruses five viroids are known to be pollen transmitted. We investigated whether reverse transcription‐polymerase chain reaction (RT‐PCR) could used detect reliably in pollen. Four extraction methods yielded nucleic acid appropriate quantity quality from Tobacco ringspot virus (TRSV)‐infected RT‐PCR amplification. One method, the RNeasy ® Plant Mini Kit was subsequently extract amplifiable...
ISHS I International Symposium on Biotechnology of Fruit Species: BIOTECHFRUIT2008 USING FUNCTIONAL GENOMICS TO IDENTIFY MOLECULAR MARKERS FOR FIRE BLIGHT RESISTANCE (ERWINIA AMYLOVORA) IN APPLE (MALUS)
Summary The utility of quantitative Hepatitis B surface antigen ( qHBsA g) level as a marker chronic hepatitis CHB )‐related liver damage is not fully delineated, but becoming increasingly relevant. Quantitative HB sAg levels are linked with progression disease in eAg‐negative genotype and C patients, it clear whether this consistent across all HBV genotypes. In single‐centre, cross‐sectional observational study, we evaluated g can predict the severity E patients. Demographic...
Summary We aimed to investigate the ability of HBsA g plasma level kinetics predict therapy response by studying 23 children with infancy‐acquired chronic hepatitis B ( CHB ) during combination sequential lead‐in lamivudine LAM and add‐on interferon‐α IFN ‐α) [5 responders R = anti‐ HB s seroconversion) 18 nonresponders NR )] assess their relationship pretreatment intrahepatic HBV ‐ DNA ccc A c liver expression. Plasma levels were measured in samples before (treatment week 0 TW 0), 9, 28,...
Fire blight a bacterial disease caused by Erwinia amylovora is an ongoing problem for pipfruit growers with few control options available Most commercial cultivars and rootstocks are highly susceptible to the Breeding of fire blightresistant scions manage major goal New Zealand apple breeding programme The main mode establishment through flowers However currently evaluates resistance shoot inoculations This study compared degree in 109 progeny from Royal Gala times; Malus robusta Robusta 5...
Journal Article Problems Encountered in the Culture of Isolated Pollen a Burley Cultivar Nicotiana tabacum Get access M. HORNER, HORNER Botanical Laboratories, University LeicesterLeicester LE1 7RH, England Search for other works by this author on: Oxford Academic PubMed Google Scholar H. E. STREET Experimental Botany, Volume 29, Issue 1, February 1978, Pages 217–226, https://doi.org/10.1093/jxb/29.1.217 Published: 01 1978 history Received: 21 July 1977
Abstract Fire blight, caused by Erwinia amylovora, can be spread through orchards and nurseries because of poor sanitation practices such as contaminated secateurs. This research investigated the efficacy 12 commercial sterilants at varying concentrations to kill E. amylovora on Secateurs were dipped into an inoculum solution (10 6 colony forming units/mL), then misted with a test sterilant. After 10 s, secateurs swabbed plated onto Kings B agar plate, incubated 26 °C for 48 h bacterial...