A5101846014- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Surface Modification and Superhydrophobicity
- Oxidative Organic Chemistry Reactions
- Circular RNAs in diseases
- Intestinal Malrotation and Obstruction Disorders
- Bioactive Compounds and Antitumor Agents
- Infant Nutrition and Health
- Sepsis Diagnosis and Treatment
- Phytochemical compounds biological activities
- Supramolecular Self-Assembly in Materials
- Axial and Atropisomeric Chirality Synthesis
- Surfactants and Colloidal Systems
- Cyclopropane Reaction Mechanisms
- Genomics, phytochemicals, and oxidative stress
- Signaling Pathways in Disease
- Lipid Membrane Structure and Behavior
- Adipokines, Inflammation, and Metabolic Diseases
- Silicone and Siloxane Chemistry
- Neuroinflammation and Neurodegeneration Mechanisms
- interferon and immune responses
- Antiplatelet Therapy and Cardiovascular Diseases
- Neurological Disease Mechanisms and Treatments
- Cancer Mechanisms and Therapy
- RNA modifications and cancer
Zhongkai University of Agriculture and Engineering
2025
Northwest University
2021
Nanjing Medical University
2021
Zhejiang University
2021
State Key Laboratory of Diagnosis and Treatment of Infectious Diseases
2021
Children's Hospital of Fudan University
2019-2020
Peking University
1988-2018
Chinese PLA General Hospital
2016
Shanghai University of Traditional Chinese Medicine
2014
Highly transparent anti-smudge coatings are attractive for diverse fields due to their inherent repellency against various contaminants and the ability keep surfaces clean. In this work, a novel fluorine-free coating system was developed by using poly(dimethysiloxane), tris(hydroxymethyl) aminomethane, isophorone diisocynate synthesize hexa-functional precursor utilizing hexamethylene diisocyanate trimer as curing agent. The resultant highly can be applied substrates. These exhibit water,...
In this work, a biobased cationically photocurable omniphobic coating system was effectively developed via facile strategy by using epoxidized soybean oil as biomass precursor, tetrakis [(epoxycyclohexyl) ethyl] tetramethylcyclotetrasiloxane an effective cross-linking agent, and polydimethylsiloxane agent to provide coatings with low surface energy. Due the rational design of system, no extrinsic organic solvent added, 20 s ultraviolet radiation sufficient for curing. The as-prepared were...
Previously, we identified six miRNAs that are differentially expressed in colorectal cancer compared with healthy controls. Here, tested them gastric GC.We performed quantitative RT-PCR on serum samples from 92 patients and 89 controls for the miRNAs, analyzed their risk scores to evaluate diagnostic value of miRNA profiling system.After a two-phase selection validation process, five were found significantly differ expression between control samples, including miR-21, miR-31, miR-92a,...
Electrically conductive hydrogels based on conducting polymers have found increased use in bioelectronics due to their low moduli that mimic biological tissues, ability transport both ionic and electronic charges, ease of processing various form factors via printing or injection. Current approaches towards hydrogels, however, rely covalent therefore irreversible crosslinking mechanisms. Here, we report a thermo-responsive polymer (TR-CP) undergoes fully reversible non-covalent at 35 °C...
A copper(II) trifluoromethanesulfonate via Prins reaction between salicylaldehydes and allyl alcohols is realized under mild conditions. series of compounds containing dioxabenzobicyclo[3.2.1]octane motifs are obtained in moderate to good yields. The current method can efficiently construct the valuable structural motif from easily accessed starting materials, providing a smooth build benzobicyclo skeletons.
Abstract Background Studies of microbiota composition infants with small intestinal ostomy due to various etiologies are limited. Here, we characterized the neonates ileostomy resulting from distinct primary diseases. Methods Fifteen patients necrotizing enterocolitis, eight meconium peritonitis, and seven Hirschsprung’s disease were included in study. The caused by these diseases was studied. Results Microbial diversity neonatal fluid generally low, dominated members Proteobacteria...
Background: Tamoxifen (TAM) is the eminent first-line drug for endocrine therapy of hormone receptor positive premenopausal breast cancer and reduces risk recurrence by ∼50%. However, many patients developed TAM resistance their diseases recurred. Our previous study on transcriptome profile resistant cells revealed that TMEM47 one most significantly differentially expressed genes. The mechanism how involved in was not known. Methods: We constructed a mammal cell line, which stably...
Vacuum-assisted technology, favored for its low cost, environmental friendliness, and scalability, is widely used in perovskite solar cells a preferred choice commercialized production. However, strong solvent extraction...
Chemoprevention of cancer with aspirin is controversial as a primary prevention strategy. We sought to investigate the association between frequency and risk lung in The Prostate, Lung, Colorectal Ovarian (PLCO) Cancer Screening Trial.Using data from 101,722 participants PLCO, we used Cox regression model coupling propensity score detect risk.High-frequency use significantly increased by 28% compared no (HR =1.28; 95% CI, 1.14-1.45; P=3.37×10-5), especially for current smoker =1.30;...
L-3-n-butylphthalide (NBP) is used for treatment of mild and moderate acute ischemic stroke, exerts its effect by modulating the Nrf2 pathway. However, studies have not explored whether NBP preventive effects in high-risk groups stroke through In current study, pathway was after long-term pretreatment dMCAO model mice. Nrf2+/+ wild-type Nrf2−/− knockout mice were randomly divided into vehicle group (equal volume vegetable oil), NBP-low-dose (20 mg/kg) NBP-high-dose (60 mg/kg). The drug...
Abstract Aim: To investigate the association between loss of genomic imprinting (LOI) insulin-like growth factor 2 (IGF-2) gene and expressions genes related with type I receptor (IGF1R) signaling cancer stem cell associated (CD133 Musashi I), in gastric (GC) its adjacent normal mucosa GC patients without IGF-2 LOI. Patients methods: pathological diagnosis underwent surgical resection Department Surgery Potuo Hospital from 2006 to 2012 were recruited. Demographic clinical data retrieved...
Objective To explore the value of plasma procalcitonin (PCT) to lactate ratio in predicting infection patients with diabetic ketoacidosis (DKA). Methods A prospective cohort study 81 DKA department endocrinology or emergency medicine hospital were divided into two groups. The group (n=30) and non-infection (n=51). following information was obtained from participants' records on admission: age, sex, body mass index (BMI), duration type 2 diabetes mellitus (T2DM), types diabetes. All...
Abstract Background: Studies on microbiota characteristics of infants with small intestinal ostomy due to various etiologies are limited. Here, we investigated the neonates ileostomy different primary diseases. Methods: Fifteen patients necrotizing enterocolitis, eight meconium peritonitis, and seven Hirschsprung's disease were included in study. The composition caused by was investigated. Results: microbial diversity neonatal fluid generally low, dominated Proteobacteria Firmicutes members....
Abstract The perylenequinone (III) is synthesized according to the reaction scheme.