- Global Health and Surgery
- Global Health Workforce Issues
- Diversity and Career in Medicine
- Congenital Anomalies and Fetal Surgery
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Surgical Simulation and Training
- Angiogenesis and VEGF in Cancer
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Global Maternal and Child Health
- Healthcare Policy and Management
- Coronary Interventions and Diagnostics
- Travel-related health issues
- Cardiovascular Health and Disease Prevention
- Childhood Cancer Survivors' Quality of Life
- Gastrointestinal disorders and treatments
- Child and Adolescent Health
- Hernia repair and management
- Abdominal Surgery and Complications
- Advanced MRI Techniques and Applications
- Advances in Oncology and Radiotherapy
- Appendicitis Diagnosis and Management
Duke University
2017-2025
Duke Medical Center
2017-2025
Duke Institute for Health Innovation
2020-2024
Howard University
2024
Duke University Hospital
2018-2024
University of Pittsburgh Medical Center
2024
Mulago Hospital
2022
Massachusetts General Hospital
2021
Mbarara University of Science and Technology
2018-2021
Makerere University
2018-2020
Ephrin ligands and Eph receptors are signaling molecules that differentially expressed on arteries veins during development. We examined whether Eph-B4, a venous marker, Ephrin-B2, an arterial regulated vein graft adaptation in humans aged rats.Eph-B4 transcripts immunodetectable protein downregulated endothelial smooth muscle cells of patent grafts both rats, whereas Ephrin-B2 not strongly induced. Other markers identity, including dll4 notch-4, also induced rats. Because VEGF-A is upstream...
Recommendations by the Lancet Commission on Global Surgery regarding surgical care in low- and middle-income countries (LMICs) require development to address needs of children. The Initiative for Children's (GICS) was founded 2016 identify solutions problems children's surgery utilizing expertise practitioners from around world. This report details this unique process underlying principles.Three global meetings convened providers services Through working group meetings, participants reviewed...
SignificanceLaparoscopic surgery is generally unavailable in low- and middle-income countries (LMICs) due to the high cost of installation lack qualified personnel maintain repair equipment. We developed a low-cost, durable, reusable laparoscopic system, called KeyScope laparoscope, for use LMICs. To reliably build service LMICs, portable testing chamber (PTC) needed assess image performance.AimA PTC was characterize laparoscope performance LMICs.ApproachImages standard resolution, color...
Pseudomembranous colitis has increased in incidence and severity over the past 10 years. Toxic megacolon is a rare but reported presentation of severe pseudomembranous colitis. This article reviews cases Clostridium difficile with toxic literature introduces an additional case that underscores importance early diagnosis guiding appropriate therapy.A systematic review was performed to identify previous reports presenting megacolon, outcomes each these analyzed. The focused on atypical...
Inguinal hernias are common in both the paediatric and adult population worldwide. When repaired electively, there minimal complications recurrence rate can be decreased with use of mesh. Emergency repair is more often associated bowel spermatic cord injury, as well other complications. However, a large discrepancy access to surgical availability mesh between low-income middle-income countries (LMICs) high-income countries.1Estridge P Sanders DL Kingsnorth AN Worldwide hernia repair:...
Abstract Vascular smooth muscle cells (SMC) may be directly exposed to blood flow after an endothelial‐denuding injury. It is not known whether direct exposure of SMC shear stress reduces turnover and contributes the low rate restenosis most vascular interventions. This study examines if laminar inhibits proliferation or stimulates apoptosis. Bovine aortic were arterial magnitudes (11 dynes/cm 2 ) for up 24 h compared control (0 ). density was assessed by cell counting, DNA synthesis 3...
Improving access to surgical care in India requires policy-level prioritization of surgical, obstetric, trauma, and anesthesia (SOTA) care. We quantified SOTA the last seven decades by analyzing India’s national policy programmatic documents. Forty documents importance over (1946–2017) were screened for a set 52 6 non-surgical keywords. The number mentions per keyword was used as proxy prioritization. For thematic analysis, further classified into five domains: Infrastructure, Workforce,...
Summary Pediatric surgeons, anesthesia providers, and nurses from North America other high‐income countries are increasingly engaged in resource‐limited areas, with short‐term missions as the most common form of involvement. However, consensus recommendations currently do not exist for pediatric general surgery associated perioperative care. The American Academy Pediatrics (AAP) Delivery Surgical Care Subcommittee Association (APSA) Global Surgery Committee, Nurses Association, Inc. ( APSNA...