A5054579436- Cervical Cancer and HPV Research
- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Reproductive tract infections research
- Genital Health and Disease
- Global Cancer Incidence and Screening
- Uterine Myomas and Treatments
- Intraperitoneal and Appendiceal Malignancies
- Estrogen and related hormone effects
- Protease and Inhibitor Mechanisms
- Menopause: Health Impacts and Treatments
- Colorectal and Anal Carcinomas
- Cell Adhesion Molecules Research
- Molecular Biology Techniques and Applications
- Bone health and osteoporosis research
- Cancer Risks and Factors
- Colorectal Cancer Screening and Detection
- Hepatitis B Virus Studies
- Galectins and Cancer Biology
- Cancer survivorship and care
- Advanced Chemical Sensor Technologies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Urinary and Genital Oncology Studies
- Angiogenesis and VEGF in Cancer
Linköping University
2024-2025
Linköping University Hospital
2025
Skåne University Hospital
2015-2024
Lund University
2015-2024
Fundación Juan March
2022
University of Inland Norway
2022
Karolinska University Hospital
2022
Uppsala University Hospital
2022
Creative Commons
2022
Karlstad University
2022
The Groningen International Study on Sentinel nodes in Vulvar cancer (GROINSS-V)-II investigated whether inguinofemoral radiotherapy is a safe alternative to lymphadenectomy (IFL) vulvar patients with metastatic sentinel node (SN).GROINSS-V-II was prospective multicenter phase-II single-arm treatment trial, including early-stage (diameter < 4 cm) without signs of lymph involvement at imaging, who had primary surgical (local excision SN biopsy). Where the involved (metastasis any size), given...
Background: The aim of this study is to evaluate the impact lymphovascular space invasion (LVSI) on risk lymph node metastases and survival in endometrioid endometrial adenocarcinoma.Material methods: As regard design, a cohort based prospectively recorded data. Patients with adenocarcinoma registered Swedish Quality Registry for Gynecologic Cancer 2010-2017 FIGO stages I-III verified nodal status were identified (n = 1587). LVSI together established factors, namely DNA ploidy, grade,...
Abstract Objective To investigate the occurrence rate of adnexal lesions in premenopausal women. Methods A random sample women 25–40 years old was invited to undergo a transvaginal ultrasound examination, and 335 were examined. The criteria used define an lesion either cystic with its largest diameter at least 25 mm within pelvic region, or appearance solid parts any regardless size. Results Adnexal found 26/335 cases, (7.8%) (95% confidence interval (CI), ± 2.9%). ovarian cysts 22/335...
Background. The aim was to evaluate whether patients with benign ovarian cysts, functional or endometriosis have an increased risk of developing gynecologic cancer. Methods. Swedish Hospital Discharge Register used identify a cohort women discharged from hospital the diagnoses cyst ( n = 42 217), 17 998), 28 163). To each case, three controls were matched. National Cancer matched all incident cancers diagnosed among cases and controls. From Fertility Register, date birth children born...
Background. In articles and textbooks the prevalence of uterine leiomyomas is said to be 20–25% in women over age 30. The aim this study was investigate rate leiomyoma, thickness texture endometrium, size uterus a random sample asymptomatic 25–40 years old. Methods. A old offered transvaginal ultrasonographic examination 335 (72%) accepted invitation. Results. 18 were detected, i.e. 5.4% (95% CI 3.0–7.8%). increased with age, being 3.3% 0.7–6.0%) 25–32 group 7.8% 3.6–12.0%) 33–40 group....
Abstract The aim of this study was to assess the clinical value preoperative blood levels HE4 as a predictor overall survival in patients with ovarian cancer and validate previous data ROMA algorithm including CA125 discriminating benign malignant tumors. Experimental design plasma were analyzed ELISA 312 adnexal lesions. Tumors classified (n= 206), borderline (i.e. low potential tumors) 25), well 14), moderately 15), poorly 51) differentiated malignant. Results In univariate Cox regression...
Abstract Purpose: To evaluate the plasma level of different forms soluble urokinase plasminogen activator receptor (suPAR) as discriminators between malignant, borderline, and benign ovarian tumors prognostic markers in patients with cancer. Experimental Design: The suPAR were measured preoperative samples obtained from 335 adnexal lesions using three time-resolved fluoresence assays (TR-FIA): TR-FIA 1 measuring intact suPAR, suPAR(I-III), 2 total amount suPAR(I-III) cleaved form,...
Aim: The aim of this study is to evaluate the quality data on endometrial (EC) and ovarian, fallopian tube, peritoneal, abdominal or pelvic cancers (OC) registered in Swedish Quality Register Gynecologic Cancer (SQRGC).Method: A random sample 500 patients was identified SQRGC their medical charts were reviewed for re-abstraction 31 selected core variables by an independent validator. re-abstracted compared. collected from 25 hospitals evenly distributed throughout Sweden. main outcomes...
Background Recent research indicates a favourable influence of postmenopausal hormone therapy (HT) if initiated early, but not late, on subclinical atherosclerosis. However, the clinical relevance timing HT initiation for hard end points such as stroke remains to be determined. Further, no previous has considered in relation haemorrhagic risk. The importance route administration, type, active ingredient, and duration risk is also unclear. We aimed assess association between stroke,...
<title>Abstract</title> <bold>Introduction: </bold>Sexually transmitted infections (STIs) continue to be a major public health concern and threat on global scale. This study aimed determine the prevalence association of STIs coinfection with hrHPV histological findings in cohort women attending cervical cancer screening self-sampling. <bold>Method:</bold> was based 885 reproductive-aged at prenatal care clinics Adama, Ethiopia. The detection performed by using Allplex™ STI-EA real-time...
Background: In Sweden, the cervical cancer screening programme is based on primary human papillomavirus (HPV) testing with either clinician-collected sampling or home-based vaginal self-sampling. We assessed effectiveness and cost-effectiveness of HPV self-collected for unvaccinated cohorts Swedish women. Methods: A model-based analysis was performed to project long-term costs quality-adjusted life-years (QALYs). Screening strategies included no screening, 18 36 self-sampling strategies,...
Abstract High‐risk human papillomavirus (hrHPV) genotype is needed for adequate cervical cancer screening and HPV vaccination program evaluation as recommended by different guidelines. We aimed to assess the rate of infection distribution using vaginal self‐sampling in a cohort unscreened reproductive‐age women Ethiopia. A community‐based study was conducted with aged 23–46 living Adama, total 885 self‐collected swabs were obtained tested hrHPV genotypes real‐time polymerase chain reaction...
Background: The primary cause of cervical cancer is the high-risk human papillomavirus (hrHPV); infection patterns may vary depending on state vaginal immune system. Sexually transmitted infections (STIs) such as gonorrhea, trichomoniasis, and chlamydia can alter local response, which in turn affect persistence progression rate hrHPV infections. objective this study was to compare cytokine levels from specimens collected positive, STI healthy controls, explore correlations with clinical...
Abstract Introduction Most cervical cancer cases in Sweden are diagnosed among women who have failed to attend screening. The objective of this study was analyze the effectiveness offering vaginal HPV (human papillomavirus) self‐samples long‐term non‐attendees as a routine screening program, which had already been targets several interventions. Material and Methods Register data from organized program were used population‐based study. From January 2016 December 2019, 33 881 high‐risk (hr‐)...