To investigate the prevalence of cognitive impairment and its risk factors among Chinese elders aged over 80 years, a community-based, cross-sectional study was conducted from May to June 2016 in Shanghai, China. Cognitive function measured by using Mini-Mental Status Examination. Multiple logistic regression assessed associations between impairment. Of 480 participants, 30% were diagnosed with Women [adjusted odds ratio (AOR): 1.71, 95% confidence interval (CI): 1.03-2.83], solitary life...

Objective: To analyze the trend of health literacy level Chinese residents from 2012 to 2023 and predict 2024 2027. Methods: The study collected data on surveillance 2023. Joinpoint regression model was used calculate average annual percent change (AAPC) trend. interrupted time series analysis with Prais-Winsten transformed generalized least squares estimation employed investigate impact the"Healthy China 2030" policy residents' levels. regression, autoregressive integrated moving grey...

Background: It is still uncertain how multimorbidity patterns affect transitions between fall states among middle-aged and older Chinese. Methods: Data were obtained from China Health Retirement Longitudinal Study (CHARLS) 2011–2018. We utilized latent class analysis to categorize baseline patterns, Markov multi-state model explore the impact of characterized by condition counts on subsequent transitions, Cox proportional hazard models assess ratios each transition. Results: A total 14,244...

<ns3:p>Obesity and short sleep duration have both been associated with an increased risk of dementia, but their combined impact the underlying mechanisms are not yet fully understood. Our aim is to investigate separate associations obesity cognitive decline dementia risk, whether these mediated by neuroinflammatory responses metabolic disturbances, as indicated blood-based biomarkers. This a prospective cohort study adults who were free had data on BMI at baseline in 1997-1999, tracked for...

We aim to develop and validate an interpretable machine-learning model that can provide critical information for the clinical treatment of critically ill patients with acute myocardial infarction (AMI). All data was extracted from multi-centre database (training internal validation cohorts: MIMIC-III/-IV, external cohort: eICU). After comparing different models several unbalanced processing methods, best performance selected. Lasso regression used build a compact model. Seven evaluation PR,...

There is a greater likelihood of anxiety and depression among older adults who suffer falls. This study examined the relationships falls severe with depressive symptoms, moderating role psychological resilience on these associations.Our recruited participants from 2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS), nationally representative cohort study. A total 11,857 included in analysis. We used linear regression model to investigate relationship between falls/severe...

Abstract Background It remains unclear whether plant-based or animal-based dietary patterns are more beneficial for older adults in maintaining muscle mass. Using a prospective cohort with nationwide sample of China this study, we aimed to examine the relationship between adhering diet and loss. Methods We included 2771 (≥ 65 years) from Chinese Longitudinal Health Longevity Survey (CLHLS) normal mass at baseline (2011 2014 waves), which followed up into 2018. Plant-based pattern scores...

Abstract Objective To examine the bi-directorial association between diversified leisure activity participation and cognitive function over a 7-year period. Methods Data analyzed was from Chinese Longitudinal Healthy Longevity Survey (CLHLS), large-scale longitudinal national study. The baseline survey conducted in 2011 with follow-up every three years. We traced total of 2718 participants period 7 used adjusted random intercept cross-lagged panel models (RI-CLPMs) to associations function....

Objective We conducted a community-based cohort study to predict the 3-year occurrence of chronic kidney disease (CKD) among population aged ≥60 years.

Abstract Background Lower socioeconomic status (SES) is a risk factor for poor cognitive function, while healthy lifestyle associated with better function. We examined the complex relationship between SES and function among older Chinese adults. Methods used national prospective cohort of Longitudinal Healthy Longevity Survey (CLHLS) from 2008–18, aged 65 years normal cognition at baseline. Participants were categorised into favourable group if they had four to six factors unfavourable zero...

Abstract Background Health literacy is one of the important determinants healthy aging, yet few studies have focused on association between health and falls. Aims This study aims to explore relationship falls, with a focus sex differences among older people in China. Methods cross-sectional enrolled 2,144 aged ≥ 60 years from Shandong Province, China 2021. We used general screening scale assess literacy, collected incidence falls past year. Logistic regression models were employed analyze...

Abstract Background The global prevalence of chronic kidney disease (CKD) in the general population is relatively clear. Our previous study showed that elderly individuals who are physically disabled more likely to experience function impairment, and main purpose this was determine risk factors associated with CKD patients physical disabilities. Methods A total 2679 disabilities from 2018 Shanghai Disability Health Survey were screened calculate CKD. Multiple logistic regression performed...

We aimed to examine the longitudinal association between frailty and cognitive impairment in older Chinese population. This prospective cohort study used data from Longitudinal Healthy Longevity Study 2011 wave. calculated follow-up duration as 3 years baseline year. Frailty was measured using index, function by Mini-Mental State Examination Scale. Participants who were non-frailty those with normal included followed up 2014, respectively. an independent risk factor for early-onset...

Female-specific cancers seriously affect physical and psychological health of women worldwide.We aimed to elucidate trends in the age-standardized mortality rates (ASMRs) breast cancer, cervical uterine ovarian cancer female populations with different socioeconomic statuses China countries Human Development Index (HDI).A longitudinal study was performed using data death other 39 countries. The were standardized Segi's world population. Trends mortalities exhibited by estimated annual...

Abstract Background This study aimed to explore the associations between household air pollution (HAP), measured by cooking fuel use, sensory impairments (SI), and their transitions in Chinese middle-aged older adults. Methods Participants were recruited from 2011 China Health Retirement Longitudinal Study (CHARLS) subsequently followed up until 2018. Data on SI collected self-reported hearing vision impairments, which divided into three categories: non-SI, single (hearing or impairment),...

Hypertension has become increasingly prevalent in Chinese children and adolescents recent decades, which affects growth development of children, leads to cognitive decline multiple target organ damage. Here, we assessed the impact different body mass index (BMI) trajectories on occurrence hypertension using a cohort study Northeast China.Children aged 5-18 years was extracted for physical examination Fuxin City, Liaoning Province, China during 2009-2015 period. A latent category mixed model...

Any single discrete blood pressure (BP) measurement is not enough to estimate adverse cardiovascular events. We aim comprehensively investigate the association between BP indicators and stroke.An observational cohort study was conducted among 2888 Shanghai community-aged residents from 2014 2018, a nested case-control designed identify stroke. In total 415 cases of stroke detected during period were selected as case group non-stroke subjects, matched with factors age gender, randomly control...

The effects of statins on renal outcomes have already been studied in patients with chronic kidney disease (CKD); however, data the general population are limited. We evaluated association between statin use and risk CKD community-dwelling older people Shanghai, China.This registry-based cohort study was conducted four communities districts Shanghai. Participants an estimated glomerular filtration rate (eGFR) ≥ 60 mL/min/1.73 m2 2016 were eligible for study, new-onset 2017, 2018, 2019...

Objective . Capillary glycated hemoglobin (HbA1c) may enhance screening for childhood prediabetes and diabetes, but variations in this parameter remain unclear. We aimed to develop percentiles of HbA1c explore the influence various variables on level among Chinese children. Study Design Methods The data were derived from Shanghai Children’s Health Nutrition Community‐based Epidemiologic Survey (CHANCE). A total 4,615 children aged 3–12 years included. capillary was measured using...

Despite excellent 5-year survival, there are limited data on the long-term prognostic characteristics of clinical stage IA part-solid lung adenocarcinoma. The objective was to elucidate dynamics through conditional survival analysis.

Investigations have indicated that there is a correlation between thyroid nodules and patients’negative emotions. Nevertheless, the risk factors contributing to development of negative emotions in nodule patients remain unidentified. This cross-sectional study recruited 150 diagnosed with through ultrasound examination from January 2022 2023 at Jinan Central Hospital, Second Affiliated Hospital Shandong First Medical University, Qingyun County Maternal Child Health as case group, which were...