A5053097318- HIV/AIDS Research and Interventions
- HIV Research and Treatment
- HIV-related health complications and treatments
- HIV, Drug Use, Sexual Risk
- HIV/AIDS drug development and treatment
- Hepatitis C virus research
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS Impact and Responses
- Hepatitis B Virus Studies
- Cytomegalovirus and herpesvirus research
- Hepatitis Viruses Studies and Epidemiology
- Streptococcal Infections and Treatments
- Syphilis Diagnosis and Treatment
- Reproductive tract infections research
- Infectious Diseases and Tuberculosis
- Urinary Tract Infections Management
- Sex work and related issues
- Infective Endocarditis Diagnosis and Management
- Immunodeficiency and Autoimmune Disorders
- Cardiovascular Disease and Adiposity
- Urinary Bladder and Prostate Research
- Liver Disease Diagnosis and Treatment
- Herpesvirus Infections and Treatments
- Viral-associated cancers and disorders
- Otolaryngology and Infectious Diseases
University Hospital for Infectious Diseases "Dr Fran Mihaljevic"
2014-2024
University Hospital Centre Zagreb
2015-2024
University of Zagreb
2015-2024
University Hospital Bonn
2023
National Center for Epidemiology
2022
Children's Hospital Zagreb
2022
Centre of Excellence for Health, Immunity and Infections
2020
University of Copenhagen
2020
Rigshospitalet
2020
Hospital for Tropical Diseases
2018
Many practical clinical questions regarding the management of human immunodeficiency virus (HIV)–associated neurocognitive disorder (HAND) remain unanswered. We sought to identify and develop answers key in HAND management. Sixty-six specialists from 30 countries provided input into program, which was overseen by a steering committee. Fourteen were rated as being greatest importance. Answers drafted an expert group based on comprehensive literature review. Sixty-three experts convened...
Improved methods for targeting HIV testing among patients most likely to be infected are required; HIDES I aimed define the methodology of a European wide study prevalence in individuals presenting with one eight indicator conditions/diseases (ID); sexually transmitted infection, lymphoma, cervical or anal cancer/dysplasia, herpes zoster, hepatitis B/C, mononucleosis-like illness, unexplained leukocytopenia/thrombocytopenia and seborrheic dermatitis/exanthema, identify those an >0.1%, level...
IntroductionThe SARS-CoV-2 pandemic has hit the European region disproportionately. Many HIV clinics share staff and logistics with infectious disease facilities, which are now on frontline in tackling COVID-19. Therefore, this study investigated impact of current situation care continuity antiretroviral treatment (ART) supplies CEE countries.MethodsThe Euroguidelines Central Eastern Europe (ECEE) Network Group was established February 2016 to review standards for region. The group consists...
Exposure prevention is the primary strategy to reduce risk of occupational bloodborne pathogen infections in healthcare workers (HCW). HCWs should be made aware medicolegal and clinical relevance reporting an exposure, have ready access expert consultants receive appropriate counselling, treatment follow-up. Vaccination against hepatitis B virus (HBV), demonstration immunisation before employment are strongly recommended. with postvaccinal anti-HBs levels, 1-2 months after vaccine...
Testing for HIV is one of the cornerstones in fight against spread. The 2014 European Guideline on provides advice testing infection individuals aged 16 years and older who present to sexually transmitted infection, genito-urinary or dermato-venereology clinics across Europe. It may also be applied other clinical settings where required, particularly primary care settings. aim guideline provide practical guidance clinicians laboratories that within these undertake testing, indicate standards...
European guidelines recommend the routine offer of an HIV test in patients with a number AIDS-defining and non-AIDS conditions believed to share association HIV; so called indicator (IC). Adherence this guidance across Europe is not known. We audited testing behaviour accessing care for ICs. Participating centres reviewed case notes either 100 or all consecutive one year, presenting each following ICs: tuberculosis, non-Hodgkins lymphoma, anal cervical cancer, hepatitis B C oesophageal...
Objectives Understanding the public health impact of lymphogranuloma venereum (LGV) in Europe is hampered by inadequate diagnostics and surveillance systems many European countries. We developed piloted LGV three countries without existing performed a preliminary investigation epidemiology, where little evidence currently exists. Methods recruited STI or dermatovenereology clinics associated laboratories serving men who have sex with (MSM) Austria, Croatia Slovenia, using UK for comparison....
During the initial phase of COVID-19 pandemic, there was great enthusiasm for use azithromycin with or without hydroxychloroquine.We analyzed consumption in Croatia 2020 and compared this to period 2017-2019.Azithromycin evaluated using IQVIA Adriatic d.o.o. database which collects data on distribution from wholesale pharmacies hospital non-hospital Croatia. We January 2017 December 2020. Azithromycin measured as days therapy (DOT) reported per 1000 inhabitants inhabitant-days.In 2017-2020,...
Abstract Background With integrase strand transfer inhibitor (INSTI) use associated with increased body mass index (BMI) and BMI increases higher diabetes mellitus (DM) risk, we explored the relationships between INSTI/non-INSTI regimens, changes, DM risk. Methods RESPOND participants were included if they had CD4, human immunodeficiency virus (HIV) RNA, ≥2 measurements during follow-up. Those prior excluded. was defined as a random blood glucose ≥11.1 mmol/L, hemoglobin A1c ≥6.5%/48...
The spectrum of neurological complications HIV‐infection has remained unchanged through the years, but its epidemiology changed remarkably as a result introduction highly active antiretroviral therapy (HAART). Guidelines for diagnosis and treatment cerebral toxoplasmosis, cryptococcal meningitis, progressive multifocal leukoencephalopathy, CMV encephalitis, polyradiculomyelitis, tuberculous primary CNS lymphoma, HIV dementia, myelopathy polyneuropathy are given with grading evidence recommendations.
The aim of the study was to assess socio-demographical characteristics, clinical presentation, and outcomes in patients diagnosed with mpox.
Background It is cost-effective to perform an HIV test in people with specific indicator conditions (IC) undiagnosed prevalence of at least 0.1%. Our aim was determine the for 14 different across 20 European countries. Methods Individuals aged 18–65 years presenting care one ICs between January 2012 and June 2014 were included routinely offered test. Logistic regression assessed factors associated testing positive. Patients infectious mononucleosis-like syndrome (IMS) recruited up until...
The number of new cases HIV infection has been decreasing in some parts the world (e.g. sub-Saharan Africa) with highest burden disease recent years. However, other regions are showing a different trend, such as Eastern Europe, Middle East, North Africa and Central Asia. This trend seems also to apply European region. article analyses data for Europe derived from annual surveillance reports Centre Disease Prevention Control (ECDC) gives an overview status epidemic this specific We show that,...
With no expected vaccine for HIV in the near future, we aimed to define current situation and challenges pre- post-exposure prophylaxis (PrEP PEP) Central Eastern Europe (CEE). The Euroguidelines CEE Network Group members were invited respond a 27-item survey including questions on PrEP (response rate 91.6%). was licensed 68.2%; 95 centers offered estimated number around 9000. It available daily (40.1%), on-demand (13.3%), or both forms (33.3%). access <1−80%. Three major barriers lack of...
Objectives: Analyzing changes in causes of death over time is essential for understanding the emerging trends HIV population mortality, yet data on cause are often missing. This poses analytic limitations, as does changing approach collection by longitudinal studies, which a natural consequence an increased awareness and knowledge field. To monitor analyze mortality time, we have explored this issue within EuroSIDA study propose standardized protocol unifying collected allowing...
To determine the relationship between measures of renal function [current estimated glomerular filtration rate (eGFR) and proportion follow-up with a low eGFR (%FU ≤60 ml/min)] fatal/ nonfatal AIDS, non-AIDS events all-cause mortality.An observational, longitudinal cohort study 12 155 persons from EuroSIDA.Persons at least one measurement after 1 January 2004, using CKD-EPI formula, were included. Poisson regression analyses used to whether current or %FU 60 ml/min less independent...
Background/objectives: Inadequate HIV care for hard-to-reach populations may result in failing the UNAIDS 90–90–90 goal. Therefore, we aimed to review continuum of and each step Central, Eastern South Europe.Methods: Euro-guidelines Central Europe (ECEE) Network Group were created February 2016. The aim network was standards countries region. Information about stage collected through on-line surveys. Respondents ECEE members chosen based on their expertise involvement national care. Data...
High uptake of antiretroviral treatment (ART) is essential to reduce human immunodeficiency virus (HIV) transmission and related mortality; however, gaps in care exist. We aimed construct the continuum HIV (CoC) 2016 11 European Union (EU) countries, overall by key population sex. To estimate progress toward Joint United Nations Programme on HIV/AIDS (UNAIDS) 90-90-90 target, we compared 2013 estimates for same representing 73% region.A CoC with following 4 stages was constructed: number...
Although antiretroviral treatments have improved survival of persons living with HIV, their long-term use may limit available drug options. We estimated the prevalence heavily treatment-experienced (HTE) status and potential clinical consequences becoming HTE.EuroSIDA, a European multicenter prospective cohort study.A composite definition for HTE was developed, based on estimates resistance prior exposure to specific regimens. Risks progressing outcomes were assessed by Poisson regression,...