A5000159075- Bacterial Genetics and Biotechnology
- Genomics and Phylogenetic Studies
- Advanced Photocatalysis Techniques
- Bacteriophages and microbial interactions
- Microbial Metabolic Engineering and Bioproduction
- Probiotics and Fermented Foods
- interferon and immune responses
- Polymer Nanocomposites and Properties
- Hydrogels: synthesis, properties, applications
- Plant and animal studies
- Biofuel production and bioconversion
- Reproductive System and Pregnancy
- RNA modifications and cancer
- CRISPR and Genetic Engineering
- Chromosomal and Genetic Variations
- MicroRNA in disease regulation
- Pregnancy and preeclampsia studies
- Plant Pathogens and Resistance
- Advanced oxidation water treatment
- Building materials and conservation
- Plant biochemistry and biosynthesis
- Plant Pathogens and Fungal Diseases
- Immune Response and Inflammation
- Plant Gene Expression Analysis
- Inflammasome and immune disorders
Guangxi Medical University
2022-2024
Sichuan University
2014-2024
First Affiliated Hospital of GuangXi Medical University
2023-2024
Third Affiliated Hospital of Southern Medical University
2024
Orthopaedic Hospital
2024
Hubei University
2024
Xiangya Hospital Central South University
2021-2024
Central South University
2021-2024
Chongqing Technology and Business University
2019-2023
Xiamen University
2023
Insects are the most speciose group of animals, but phylogenetic relationships many major lineages remain unresolved. We inferred phylogeny insects from 1478 protein-coding genes. Phylogenomic analyses nucleotide and amino acid sequences, with site-specific or domain-specific substitution models, produced statistically robust congruent results resolving previously controversial relations hips. dated origin to Early Ordovician [~479 million years ago (Ma)], insect flight Devonian (~406 Ma),...
Unresolved questions about evolution of the large and diverse legume family include timing polyploidy (whole-genome duplication; WGDs) relative to origin major lineages within Fabaceae symbiotic nitrogen fixation. Previous work has established that a WGD affects most in Papilionoideae occurred sometime after divergence papilionoid mimosoid clades, but exact been unknown. The history also not for outside Papilionoideae. We investigated presence WGDs legumes by querying thousands phylogenetic...
Ubiquitin-specific protease 39(USP39) plays an important role in modulating pre-mRNA splicing and ubiquitin-proteasome dependent proteolysis as a member of conserved deubiquitylation family. Accumulating evidences prove that USP39 participates the development hepatocellular carcinoma (HCC). However, little is known about mechanism especially deubiquitinating target regulating (HCC) growth. Here, we promotes HCC cell proliferation migration by directly deubiquitin β-catenin, key molecular...
Sweet potato [Ipomoea batatas (L.) Lam] ranks among the top seven most important food crops cultivated worldwide and is hexaploid plant (2n=6x=90) in Convolvulaceae family with a genome size between 2,200 to 3,000 Mb. The genomic resources for this crop are deficient due its complicated genetic structure. Here, we report complete nucleotide sequence of chloroplast (cp) sweet potato, which circular molecule 161,303 bp typical quadripartite structure large (LSC) small (SSC) single-copy regions...
A bacterial strain, Streptomyces albogriseolus LBX-2, was isolated from a soil sample in Chengdu, China. S. LBX-2 is an aerobic and Gram-positive microorganism that capable of using the polyethylene as sole carbon source. Results scanning electron microscopy tensile tests indicated could cause damages to (PE). Suspension culture resulted weight loss PE powder over 15-day period. The growth curve assay clearly demonstrated utilization n-hexadecane n-octadecane for strain LBX-2. Phylogenetic...
ABSTRACT A novel wheat straw composite superabsorbent was prepared by graft polymerization with acrylic acid (AA), acrylamide (AM), and maleic anhydride‐modified in aqueous solution, using N , ‐methylene‐ bis ‐acrylamide (MBA) as a cross‐linker ammonium persulfate (APS) sodium bisulfite (SBS) redox initiators. Factors influencing the degree of carboxylation, such reaction time, temperature, amount anhydride, were investigated. Morphologies structure characterized fourier transform infrared...
Recurrent pregnancy loss defined as the occurrence of two or more losses before 20-24 weeks gestation, is a prevalent and significant pathological condition that impacts human reproductive health. However, underlying mechanism RPL remains unclear. This study aimed to investigate biomarkers molecular mechanisms associated with explore novel treatment strategies for clinical applications.
Abstract A corn stalk‐composite superabsorbent with water absorbency of 660 g/g within 30 min, was prepared by graft copolymerization acrylic acid (AA), acrylamide (AM), sodium 4‐styrenesulfonate (SSS), and stalk in aqueous solution after the pretreatment stalks (CS), using N,N ‐methylenebisacrylamide (MBA) as a crosslinker ammonium persulfate (APS) bisulfite (SBS) redox initiators. Factors influencing gel strength composite, such amount stalk, mass ratio to acrylamide, degree neutralization...
Zymomonas mobilis is an ethanologenic bacterium that can produce hopanoids using farnesyl pyrophosphate (FPP), which be used as the precursor by β-farnesene synthase for production. To explore possibility and bottlenecks of developing Z. production, five heterologous synthases were selected screened, AaBFS from Artemisia annua had highest titer. Recombinant strains with driven strong constitutive promoter P gap (P – ) doubled its production to 25.73 ± 0.31 mg/L compared recombinant strain...
The CRISPR/Cas system can be used to simply and efficiently edit the genomes of various species, including animals, plants, microbes. Zymomonas mobilis ZM4 is a highly efficient, ethanol-producing bacterium that contains five native plasmids. Here, we constructed pSUZM2a-Cas9 plasmid single-guide RNA expression plasmid. was express Cas9 gene cloned from Streptococcus pyogenes CICC 10464. pUC-T7sgRNA, with T7 promoter, for in vitro synthesis RNAs. This successfully employed knockout upp...
Bacillus pumilus can secret abundant extracellular enzymes, and may be used as a potential host for the industrial production of enzymes. It is necessary to understand metabolic processes during cellular growth. Here, an RNA-seq based transcriptome analysis was applied examine B. BA06 across various growth stages reveal changes under two conditions. Based on gene expression levels, metabolism pathways that were specific phases enriched by KEGG analysis. Upon entry into transition from...
Abstract Background Recently, increasing innovations improved the accuracy of next generation sequencing (NGS) data. However, validation all NGS variants increased cost and turn‐around time clinical diagnosis, therefore limited further development applications. We aimed to comprehensively assess necessity validating variants. Methods Validation data 7,601 involving 1,045 genes were collected from 5,190 samples sequenced by one five targeted capture panels two chemistries, respectively. These...
The three-dimensional (3D) conformation of chromatin is integral to the precise regulation gene expression. 3D genome and genomic variations in non-alcoholic fatty liver disease (NAFLD) are largely unknown, despite their key roles cellular function physiological processes. High-throughput chromosome capture (Hi-C), Nanopore sequencing, RNA-sequencing (RNA-seq) assays were performed on normal NAFLD mice. A high-resolution interaction map was generated examine different hierarchies including...
Spontaneous abortions (SA) is amongst the most common complications associated with pregnancy in humans, and underlying causes cannot be identified roughly half of SA cases. We found miR-135a-5p to significantly upregulated SA-associated villus tissues, yet function it plays this context has clarified. This study explored its potential as a biomarker for unexplained SA.RT-qPCR was employed appraising expression within tissues clinical diagnostic values being assessed using ROC curves. The...
Introduction The ancient ivories unearthed from the Sanxingdui Ruins site are valuable cultural relics, however, microbial biodeterioration on during temporary cold storage poses a great threat to their later long-term preservation. Methods Here, combination of high-throughput sequencing and biochemical assays was applied for in-depth investigation key deteriorative microorganisms colonizing tracing origin, as well assessment ethanol disinfection impact communities ivories. Results It...