A5015646385- Vector-Borne Animal Diseases
- Animal Disease Management and Epidemiology
- Viral Infections and Immunology Research
- Viral Infections and Vectors
- COVID-19 epidemiological studies
- Viral gastroenteritis research and epidemiology
- Parasitic infections in humans and animals
- Congenital Anomalies and Fetal Surgery
- SARS-CoV-2 and COVID-19 Research
- Agriculture and Farm Safety
- Peripheral Neuropathies and Disorders
- Vector-borne infectious diseases
- Mollusks and Parasites Studies
- Mercury impact and mitigation studies
- Multiple Sclerosis Research Studies
- COVID-19 Clinical Research Studies
- Heavy Metal Exposure and Toxicity
- Rheumatoid Arthritis Research and Therapies
- Animal Behavior and Welfare Studies
- Animal Virus Infections Studies
- Parasite Biology and Host Interactions
- Mosquito-borne diseases and control
- Viral Infections and Outbreaks Research
- Parasitic Infections and Diagnostics
- Agricultural safety and regulations
Istituto Zooprofilattico Sperimentale della Sardegna
2017-2024
University of Padua
2022-2023
Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale
2022
We describe the detection of epizootic hemorrhagic disease virus (EHDV) serotype 8 in cattle farms Sardinia and Sicily October-November 2022. The has a direct origin North Africa; its genome is identical (>99.9% nucleotide sequence identity) to EHDV strains detected Tunisia 2021.
Despite the implementation of several eradication programmes, African swine fever (ASF), a viral disease in pigs caused by DNA virus (ASFV), has been present Sardinia (Italy) since 1978. Several studies have carried out on epidemiology ASF Sardinia, aimed at attaining better understanding role risk factors related to ASFV persistence, but those did not address social aspects involved. This work sought bridge this gap, identifying main associated with persistence. With aim, study takes into...
Background Cystic echinococcosis (CE) is an important neglected zoonotic parasitic infection belonging to the subgroup of seven Neglected Zoonotic Disease (NZDs) included in World Health Organization's official list 18 Tropical Diseases (NTDs). CE causes serious global human health concerns and leads significant economic losses arising from costs medical treatment, morbidity, life impairments fatality rates cases. Moreover, endemic several Italian Regions. The aim this study perform a...
African swine fever (ASF) is a notifiable infectious disease, caused by the ASF virus (ASFV), which DNA belonging to family Asfarviridae, genus Asfivirus. This disease has gained importance in last decade after its spread several countries Eastern and Central Europe, more recently, China. Despite efforts made eradicate it, still present on Mediterranean island of Sardinia (Italy) been since 1978. risk factors have analysed previous studies; role free-ranging pigs persistence suggested, but...
The ongoing pandemic scenario, due to the coronavirus disease 2019 (COVID-19), has had a considerable impact on public health all over world. Italy was one of most affected countries, as first European full-blown outbreak occurred there. exposure Italian care workers COVID-19 may be an important risk factor for psychological distress. aim this cross-sectional study describe worries and perception being infected among Health Care Workers (HCWs) during wave pandemic. In total, 2078 HCWs...
Objectives Vaccination against COVID-19 is highly recommended to patients affected by multiple sclerosis (MS); however, the impact of MS disease-modifying therapies (DMTs) on immune response following vaccination has been only partially investigated. Here, we aimed elucidate effect DMTs humoral mRNA-based anti-SARS-CoV-2 vaccines in patients. Methods We obtained sera from 912 Sardinian and 63 healthy controls 30 days after second dose BNT162b2 vaccine tested them for SARS-CoV-2 using...
EFSA assessed the role of seropositive wild boar in African swine fever (ASF) persistence.Surveillance data from Estonia and Latvia investigated with a generalised equation method demonstrated significantly slower decline seroprevalence adult animals compared subadults.The adults, taking more than 24 months to approach zero after last detection ASFV circulation, would be poor indicator demonstrate absence virus circulation.A narrative literature review updated knowledge on mortality rate,...
From more than 40 years African swine fever (ASF) is endemic in Sardinia. Historically, areas at higher risk are located throughout some inland parts of this island where domestic pigs still illegally kept semi-wild conditions, living contact with the local wild boar population, thereby creating perfect conditions for disease endemicity. A new eradication plan (EP-ASF15-18) has been ongoing past 3 years, based on a comprehensive strategy adapted to situation and focused strong actions pig...
African swine fever (ASF) is a devastating infectious disease of domestic pigs and wild boar that spreading quickly around the world causing huge economic losses. Although development effective vaccines currently being attempted by several labs, absence globally recognized licensed makes prevention early detection even more crucial. ASF has spread across many countries in Europe about two years ago affected Italian susceptible population. In Italy, first case genotype II dates back to...
The clinical and genetic heterogeneity of Triple Negative Breast Cancer (TNBC) the lack unambiguous molecular targets contribute to inadequacy current therapeutic options for these variants. MicroRNAs (miRNA) are a class small highly conserved regulatory endogenous non-coding RNA, which can alter expression genes encoding proteins may play role in dysregulation cellular pathways. Our goal was improve knowledge pathogenesis TNBC subgroups analyzing miRNA profile, identify new prognostic...
African swine fever (ASF) severely threatens the industry worldwide, given its spread and absence of an available licensed vaccine, has caused severe economic losses. Its persistence in wild boar (WB), longer than domestic pig farms, knowledge gaps ASF epidemiology hinder virus (ASFV) eradication. Even areas where disease is effectively controlled ASFV no detected, declaring eradication difficult as seropositive WBs may still be detected. The aim this work was to estimate main...
African swine fever virus (ASFV), the cause of a devastating disease affecting domestic and wild pigs, has been present in Sardinia since 1978. In framework regional ASF eradication plan, 4484 illegal pigs were culled between December 2017 February 2020. The highest prevalence was observed municipality with free-ranging pig density, culling actions drastically reduced ASFV circulation among these animals. ASFV-antibody detected 36.7% tested animals, which apparently healthy, thus,...
African swine fever (ASF) is a viral disease of suids that frequently leads to death. There are neither licensed vaccines nor treatments available, and even though humans not susceptible the disease, serious socio-economic consequences associated with ASF have made it one most animal diseases last century. In this context, prevention early detection play key role in controlling avoiding losses pig value chain. Target biosecurity measures strong strategy against virus (ASFV) incursions farms...
Abstract Aims Age is a crucial risk factor for cardiovascular (CV) and non-CV diseases. As people age at different rates, the concept of biological has been introduced as personalized measure functional deterioration. Associations with echocardiographic quantitative traits were analysed to assess heart ageing rates their ability predict outcomes reflect age. Methods results left ventricular mass, geometry, diastolic function, atrial volume, aortic root size measured in 2614 healthy subjects....
Information on tropical Asian vertebrates has traditionally been sparse, particularly when it comes to cryptic species inhabiting the dense forests of region. Vertebrate populations are declining globally due land-use change and hunting, latter frequently referred as "defaunation." This is especially true in Asia where there extensive high human densities. Robust monitoring requires that large volumes vertebrate population data be made available for use by scientific applied communities....
The need to consider the role of social factors in efficacy farm management and, consequently, onset and persistence diseases typical animal farms is increasingly being realized worldwide. Many risk analysis studies have been conducted assess various development diseases; however, very few accounted for factors. aim this work was bridge gap, with main hypothesis that different socio-economic could be valid indicators occurrence diseases. A performed using demographic characteristics farmers...
African swine fever virus (ASFV) is the etiological agent of devastating disease (ASF), for which there currently no licensed vaccine or treatment available. ASF defined as one most serious animal diseases identified to date, due its global spread in regions Africa, Europe and Asia, causing massive economic losses. On Italian island Sardinia, has been endemic since 1978, although last control measures put place achieved a significant reduction ASF, absent from circulation April 2019. Like...
Over the last 20 years, Italy has experienced multiple incursions of different serotypes Bluetongue virus (BTV), a Culicoides-borne arbovirus, causative agent bluetongue (BT), major disease ruminants. The majority these originated from Northern Africa, likely because wind-blown dissemination infected midges. Here, we report first identification BTV-3 in Sardinia, Italy. circulation was evidenced sentinel animals located province Sud Sardegna on September 19, 2018. Prototype strain SAR2018...
Cystic Echinococcosis (CE) is a severe zoonosis caused by the larval stage of tapeworm Echinococcus granulosus. These parasites are naturally transmitted between canid definitive hosts that harbour adult in intestine, and mainly ungulate intermediate hosts, with cysts developing their internal organs. The close coexistence dog sheep incorrect hygiene management most important factors for persistence this parasitic pathology. Educational Farms (EF) farms agritourisms suitably equipped to...
From the last December 2019 a novel coronavirus (COVID-19) quickly globally spreads from China. Currently, COVID-19, defined as new pandemic declared by World Health Organization (WHO), reached over 750.000 confirmed cases worldwide. The virus spread in Italy 22nd February, and number of related arenumber is currentlystill increasing assuming important proportions. Furthermore, given that numerous relevant proportion infectedious people need hospitalization Intensive Care Unit, this may be...
African swine fever (ASF) remains the most serious pig infectious disease, and its persistence in domestic pigs wild boar (WB) is a threat for global industry. The surveillance of WB plays central role controlling disease rapidly detecting new cases. As we are close to eradicating ASF, need find any possible pockets infection even more important. In this context, passive method choice effective WB. Considering time economic resources related surveillance, prioritize these activities,...
Cystic echinococcosis (CE) is a complex zoonosis with domestic and sylvatic life-cycles, involving different intermediate definitive host species. Many previous studies have highlighted the lack of surveillance system for CE, its persistence in Italy, endemicity several Italian regions. Because absence uniform program both humans animals, disease occurrence widely underestimated. This study aimed to estimate prevalence ovine CE Italy. Survey data on Echinococcus granulosus infections sheep...
After fifty years of spread in the European continent, African swine fever (ASF) virus was detected for first time north Italy (Piedmont) a wild boar carcass December, 2021. During six months epidemic, central role boars disease transmission confirmed by more than 200 outbreaks, which occurred two different areas declared as infected. The entered domestic pig farm second temporal cluster identified center country (Lazio). Understanding ASF dynamics is prerequisite preventing spread, and...
African swine fever (ASF) is one of the most important and serious contagious hemorrhagic viral diseases affecting domestic pigs wild boar associated with high mortality rates while also having an extensive sanitary socioeconomic impact on international trade animal products. The early detection disease often hampered by inadequate surveillance. Among surveillance strategies used, passive boars considered effective method for controlling virus (ASFV). Otherwise, design a sufficiently...