A5045323506- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Agriculture and Farm Safety
- Malaria Research and Control
- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Insect symbiosis and bacterial influences
- SARS-CoV-2 and COVID-19 Research
- T-cell and Retrovirus Studies
- Ocean Acidification Effects and Responses
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Respiratory viral infections research
- Vibrio bacteria research studies
- Escherichia coli research studies
- Brucella: diagnosis, epidemiology, treatment
- Long-Term Effects of COVID-19
- Nicotinic Acetylcholine Receptors Study
- Vector-borne infectious diseases
- Cephalopods and Marine Biology
- Virology and Viral Diseases
Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale
2014-2024
In recent years, novel Bluetongue virus (BTV) serotypes have been isolated and/or sequenced by researchers within the field. During surveillance activities, we identified a putative BTV serotype in healthy goats from Sardinia, Italy. RNAs purified blood and serum samples were positive for generic real time RT-PCR c-ELISA, respectively, whereas genotyping serotyping unsuccessful. By NGS, whole genome sequence was obtained two (BTV-X ITL2015 strains 34200 33531). Overall, Seg 2 of BTV-X shows...
Abstract It is unclear whether West Nile virus (WNV) circulates between Africa and Europe, despite numerous studies supporting an African origin high transmission in Europe. We integrated genomic data with geographic observations phylogenetic phylogeographic inferences to uncover the spatial temporal viral dynamics of WNV these two continents. focused our analysis towards lineages 1 (L1) 2 (L2), most spatially widespread pathogenic lineages. Our study shows a Northern-Western L1,...
Summary In the recent years, USUTU virus (USUV), a flavivirus of Japanese encephalitis complex, has been reported in Central Europe. As part systematic surveillance programme to monitor possible entrance and/or circulation vector‐borne viruses, since 2001, sentinel‐chicken flocks were placed throughout Italian territory nearby areas considered at risk introduction. They have periodically checked for presence antibodies against flaviviruses by indirect ELISA, plaque reduction neutralization...
Epizootic haemorrhagic disease (EHD) is a viral transmitted by Culicoides biting midges that affects wild and domestic ruminants. The causative agent, EHD virus (EHDV), belongs to the family Sedoreoviridae, genus Orbivirus. has never been reported in Europe until October 2022, when was for first time detected Sicily Sardinia. After clinical cases, an intensive entomological field activity carried out five affected farms located Sardinia, with aim of assessing EHDV vector competence European...
A novel member of the Pteropine Orthoreovirus species has been isolated and sequenced for whole genome from flying foxes (Pteropus vampyrus) imported to Italy Indonesia. The new isolate named Indonesia/2010 is genetically similar Melaka virus which first this be shown responsible human respiratory disease. Our findings highlight importance as vectors potentially zoonotic viruses biological hazard that lies in import animals geographical areas are ecologically diverse Europe.
Epizootic hemorrhagic disease (EHD) is a Culicoides-borne of domestic and wild ruminants caused by EHD virus (EHDV). This circulates in multiple serotypes. In late September 2021, novel strain belonging to EHDV-8 was reported cattle farms Central–Western Tunisia, the fall 2022, same also detected Italy Spain. present study, we described occurrence deer and, preliminary identification potential Culicoides species responsible for transmission selected areas Tunisia. identified carcasses found...
The distribution of Bluetongue virus (BTV) in Europe can be represented by two distinct and interconnected epidemiological systems (episystems), each characterized different ecological characteristics vector species. This study investigated the competence Italian populations
Epizootic haemorrhagic disease (EHD), caused by the EHD virus (EHDV), is a vector-borne viral transmitted through Culicoides biting midges. EHDV comprises seven serotypes (1, 2, and 4-8), with EHDV-8 having recently emerged spread in Europe over last two years. Such event has raised concerns about significant threat posed to livestock industry. In this study, an inactivated vaccine against (vEHDV8-IZSAM) was developed. Safety efficacy of were evaluated calves clinical, serological,...
Over the last 20 years, Italy has experienced multiple incursions of different serotypes Bluetongue virus (BTV), a Culicoides-borne arbovirus, causative agent bluetongue (BT), major disease ruminants. The majority these originated from Northern Africa, likely because wind-blown dissemination infected midges. Here, we report first identification BTV-3 in Sardinia, Italy. circulation was evidenced sentinel animals located province Sud Sardegna on September 19, 2018. Prototype strain SAR2018...
West Nile virus is a re-emerging arbovirus whose impact on public health increasingly important as more and epidemics epizootics occur, particularly in America Europe, with evidence of active circulation Africa. Because birds constitute the main reservoirs, migratory movements allow diffusion various lineages world. It therefore crucial to properly control dispersion these lineages, especially because some have greater than others. This work describes development validation novel...
Epizootic hemorrhagic disease virus serotype 8 (EHDV-8) emerged in Europe for the first time late 2022. In this study, we investigated kinetics of EHDV-8 infection cattle, sheep, and goats. Following experimental with EHDV-8, four out five calves displayed fever, while another calf exhibited ulcerative crusty lesions muzzle. RNAemia peaked at day 7 post all remained relatively stable till end 78 days infection. Infectious was isolated up to 21 one calf. As far as small ruminants are...
Abstract Bluetongue (BT), caused by virus (BTV), is a disease that affects ruminants such as cattle, sheep, goats and deer. BTV transmitted female midges of the genus Culicoides . In Brazil, information on prevalence in cattle limited, so objective this work was to identify serotypes cattle. The State São Paulo divided into seven cattle‐producing regions, each them, 300 farms were randomly selected. One animal from farm (out total 1,598 farms) selected its sera tested neutralization...
Epizootic haemorrhagic disease (EHD) is an infectious non-contagious viral transmitted by Culicoides, which affects wild and domestic ruminants. The has never been reported in Europe, however recently outbreaks of EHD occurred the Mediterranean Basin. Consequently, risk that virus (EHDV) might spread Italy cannot be ignored. aim this study was to evaluate EHDV transmission Italy, case introduction, through indigenous potential vectors. In most abundant Culicoides species associated livestock...
Abstract Usutu virus (USUV), an arbovirus from the Flaviviridae family, genus Flavivirus , has recently gained increasing attention because of its potential for emergence. After his discovery in South Africa, USUV spread to other African countries, then emerged Europe where it was responsible epizootics. The been found Asia. infection humans is considered be most often asymptomatic or cause mild clinical signs. However, a few cases neurological complications such as encephalitis...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved rapidly, leading to viral lineages characterized by multiple mutations in the spike protein, which could potentially confer virus ability avoid vaccine-induced immune response, making vaccines less effective or ineffective. Here, we initially evaluated neutralization capabilities vitro serum (SN) of six samples collected from recipients BNT162b2 vaccine against 11 SARS-CoV-2 isolates belonging major that had been...
By late March 2020, Villa Caldari, a small village of the municipality Ortona (Abruzzo region), was registering an incidence rate COVID-19 cases ten times greater than overall and declared hotspot area. Twenty-two days later, epidemiological investigation sampling were performed, to evaluate SARS-CoV-2 circulation presence antibodies. Overall, 681 nasopharyngeal swabs 667 blood samples collected. Only one resident resulted in being positive for RNA viral shedding, while 73 The seroprevalence...