A5085717600- Soil Carbon and Nitrogen Dynamics
- Genomics and Phylogenetic Studies
- Genetic diversity and population structure
- Animal Nutrition and Physiology
- Gut microbiota and health
- Plant and Fungal Species Descriptions
- Plant Pathogens and Fungal Diseases
- Genetic Mapping and Diversity in Plants and Animals
- Animal Behavior and Welfare Studies
- Cancer-related molecular mechanisms research
- Terahertz technology and applications
- Rice Cultivation and Yield Improvement
- Insect and Arachnid Ecology and Behavior
- Fungal Plant Pathogen Control
- Agriculture, Soil, Plant Science
- RNA modifications and cancer
- Plant biochemistry and biosynthesis
- GABA and Rice Research
- Microbial Community Ecology and Physiology
- Soil and Water Nutrient Dynamics
- Muscle Physiology and Disorders
- Plant and animal studies
- Epigenetics and DNA Methylation
- Photonic and Optical Devices
- Silk-based biomaterials and applications
Chinese Academy of Agricultural Sciences
2021-2025
Agricultural Genomics Institute at Shenzhen
2021-2025
Northeast Agricultural University
2018-2025
Experimental Center of Subtropical Forestry
2023-2025
Chinese Academy of Forestry
2023-2025
Xuzhou Medical College
2016-2025
China Agricultural University
2020-2024
Guizhou University
2023-2024
Heilongjiang Academy of Forestry
2023
Tianjin University
2017-2023
Summary. Current therapies for chronic hepatitis B (CHB) have a number of limitations, and better treatment options are needed. Peginterferon α ‐2a (40 kDa) is superior to conventional interferon in the C. This first report on peginterferon CHB. In this phase II study, 194 patients with CHB not previously treated interferon‐ were randomized receive weekly subcutaneous doses 90, 180 or 270 μ g, 4.5 MIU three times weekly. Twenty‐four weeks therapy followed by 24 treatment‐free follow‐up. All...
Abstract Background Sect. Tuberculata belongs to Camellia , and its members are characterized by a wrinkled pericarp united filaments. All the plants in this group, which endemic China, highly valuable for exploring evolution of have great potential use as an oil source. However, due complex diverse phenotypes these species difficulty investigating them field, their evolutionary history interspecific definitions remained largely unelucidated. Results Therefore, we newly sequenced annotated...
Pulmonary arterial hypertension (PAH) is related to inflammation, and the lncRNA H19 associated with inflammation. However, whether PDGF-BB-H19-let-7b-AT1R axis contributes pathogenesis of PAH has not been thoroughly elucidated date. This study investigated role in its mechanism. In present study, SD rats, C57/BL6 mice H19−/− were injected monocrotaline (MCT) establish a model. was detected cytokine-stimulated pulmonary smooth muscle cells (PASMCs), serum lungs rats/mice. overexpression...
The return of straw to soil can help closing the nutrient cycle in agricultural ecosystems and is an effective means improving physical chemical properties soil. objective this research was evaluate effect rice on organic carbon (SOC) fractions microbial community with a 10-year plot experiment Northeast China. study involved four treatments: no (S0), low amount (S1), high (S2), abandoned farmland (AL). results indicated that labile (LOC), particulate (POC), dissolved (DOC), biomass (MBC)...
Abstract In recent decades, artificial selection has contributed greatly to meeting the demands for animal meat, eggs, and milk. However, it also resulted in changes behavior, metabolic digestive function, alterations tissue development, including brain skeleton. Our study aimed profile behavioral traits transcriptome pattern of chickens (broilers, layers, dual-purpose breeds) response selection. Broilers spent less time gathered as a group novel arena (P < 0.01), suggesting reduced...
The mechanical microenvironment regulated by cancer-associated fibroblasts (CAFs) influence tumor progression. Chemotherapeutic interventions including 5-Fluorouracil (5-Fu) are commonly used for primary treatment of patients with advanced gastric cancer (GC), and the development acquired resistance to 5-Fu limits clinical efficacy these chemotherapies. However, if how interplay between CAFs regulates GC response is poorly understood. In this study, we demonstrate that high-level expression...
Increasing evidence demonstrates that helminth and its components can ameliorate ulcerative colitis. Clonorchis sinensis (C. sinensis) is a kind of dwells in the bile ducts for many years, but roles underlying mechanisms C. sinensis-induced protection from colitis are not elucidated. In present study, mice were infected with 50 metacercariae further administrated 4% Dextran Sodium Sulfate (DSS) drinking water 7 days on 49 post-infection. The disease severity integrity gut barriers evaluated....
Abstract Continuous cropping has a negative effect on soybean yield. In this study, positioning experiment was conducted starting in 2015, with three treatments: maize–soybean rotation (SMR), 2-year maize, (SC2), and 8-year continuous (SC8). We determined yields (2015–2022) analyzed soil microbial communities, functions, metabolites composition the 0–20 cm tillage layer using metagenomics technology GC–MS during flowering 2022. Results indicated that (SC8) significantly reduced yield...
Cortex Pseudolaricis is the root bark of Pseudolarix amabilis Rehder, found only in China, and has been widely used folk antifungal remedies traditional Chinese medicine. In order to find natural agents against mango anthracnose, eight compounds, namely pseudolaric acid A (1), ethyl B (2), (3), B-O-β-d-glucoside (4), piperonylic (5), propionic (6), 3-hydroxy-4-methoxybenzoic (7), 4-(3-formyl-5-methoxyphenyl) butanoic (8) were isolated from ethanol extracts by bioassay-guided fractionation...
Summary. Previous studies in Caucasian patients showed treatment of chronic hepatitis C with pegylated interferon/ribavirin was well tolerated, and produced a higher response rate especially genotype 1 infections. However, it is unknown whether this conclusion can be extrapolated to Chinese ethnic origin. A total 153 biopsy‐proven were randomly assigned receive either weekly injection peginterferon α ‐2b 1.5 mcg/kg plus oral ribavirin (1000 or 1200 mg/day, depending on body weight) (PEG...
It has been established that Adenosine-5'-triphosphate (ATP) can activate the NLRP3 inflammasome. However, physiological effect of extracellular ATP on inflammasome activation not yet investigated. In present study, we found was indeed released during bacterial infection. By using a murine peritonitis model, also promotes fight against infection in mice. induced secretion IL-1β and chemokines by bone marrow-derived macrophages vitro. Furthermore, intraperitoneal injection elevated levels...
ATP-binding cassette (ABC) proteins can act as transporters of different substrates across biological membranes by hydrolyzing ATP. However, little information is available about ABC in Brassica rapa, an important leafy vegetable. In the present study, we carried out genome-wide identification, characterization and molecular evolution analyses gene family B. rapa 9 other plant species. A total 179 genes (BraABCs) were identified. Among them, 173 BraABCs identified on 10 chromosomes. Based...
Abstract Recent studies have demonstrated that one‐carbon metabolism plays a significant role in cancer development. Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), mitochondrial enzyme of metabolism, has been reported to be dysregulated many cancers. However, the specific and mechanism MTHFD2 lung adenocarcinoma (LUAD) still remains unclear. In this study, we evaluated clinicopathological prognostic values LUAD patients. We conducted series functional experiments vivo vitro explore...
The sect. Chrysantha Chang of plants with yellow flowers Camellia species as the "Queen Tea Family", most these are narrowly distributed endemics China and currently listed Grde-II in National Key Protected Wild Plant China. They commercially important horticultural medicinal scientific research value. However, study genetics still its infancy, to date, mitochondrial genome has been unexplored.
Rice straw return plays an important role in sustainable agricultural development, but the impact of rice on growth remains inconclusive. In this experiment, we employed a combination soil and water cultivation experiments to investigate seedling Northeast China. This study demonstrated that inhibited plant within 37 days was no longer significant after days. resulted increase iron(II) (Fe2+) concentration solution. The hydroponic test high Fe2+ significantly increased uptake Fe, reduced...
<title>Abstract</title> Oil camellia (<italic>Camellia oleifera</italic>) is an oil-bearing crop. Jiangxi Province the second-largest oil-camellia producing region in China. The performance of varieties across different regions was evaluated. Ten areas were selected, and fruit morphology, weight, moisture content, primary economic traits five ‘Changlin’ oil analysed. Differences characteristics observed. CL53 had greatest size, content pericarp fresh seeds, 100-fresh seed -dry weight....
Interleukin-18 (IL-18) has been reported to inhibit hepatitis B virus (HBV) replication in the liver of HBV transgenic mice; however, molecular mechanism its antiviral effect not fully understood. In present study, it was shown that IL-18 and receptors (IL-18R) were constitutively expressed hepatoma cell lines HepG2 HepG2.2.15 as well normal line HL-7702. We demonstrated directly inhibited cells via downregulating activities core X gene promoters. The suppressed by could be rescued...
This study aimed to explore the difference between two Chinese local broilers, one slow- and fast-growing, in their response a stress challenge. We conducted on (Weining chicken) fast-growing (Jinlinghua breeds, with 50 chickens from each breed either feed restricted 70% for 30 days as or given ad libitum evaluate effects behavior, corticosterone, microbial programming. Standing behavior was more frequent while exploration less common breeds compared slow-growing breeds. Food seeking...
Fecal microbiota transplantation (FMT) documented transplanting a donor fecal sample to receipt individual for desired physiologic effect. However, whether the gut construction, intestinal maturation, and behavioral plasticity are modulated by FMT during early life of broilers is waiting verification. To evaluate role transfer from aged (BD) another individual, 96 birds were equally divided into check (CK, control) group broiler recipient (BR) group. was conducted daily 5 12 days age...