Xiangdong Chen

ORCID: 0000-0003-3347-2947
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About
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Research Areas
  • Anesthesia and Sedative Agents
  • Anesthesia and Pain Management
  • Intensive Care Unit Cognitive Disorders
  • Pain Mechanisms and Treatments
  • Anesthesia and Neurotoxicity Research
  • Cancer, Stress, Anesthesia, and Immune Response
  • Advanced Image Fusion Techniques
  • Acupuncture Treatment Research Studies
  • Pain Management and Opioid Use
  • Nausea and vomiting management
  • Pediatric Pain Management Techniques
  • Airway Management and Intubation Techniques
  • Image and Signal Denoising Methods
  • Inflammatory mediators and NSAID effects
  • Lipid metabolism and disorders
  • Complementary and Alternative Medicine Studies
  • Advanced oxidation water treatment
  • Axon Guidance and Neuronal Signaling
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Image Enhancement Techniques
  • Delphi Technique in Research
  • Enhanced Recovery After Surgery
  • Pharmacological Effects of Natural Compounds
  • Trauma Management and Diagnosis
  • Obesity, Physical Activity, Diet

Union Hospital
2023-2025

Huazhong University of Science and Technology
2017-2025

Union Hospital
2022-2025

Northeast Agricultural University
2024

Nanjing University of Posts and Telecommunications
2014

Hanyang University
2013

So far, there is no clear pathogenesis and cure for systemic lupus erythematosus (SLE). The therapeutic benefits of existing drug therapies are far from ideal. proteome a major source targets. Therefore, new targets SLE need to be discovered. Based on the STROBE-Mendelian randomization (MR) checklist, we performed MR explore potential SLE, using genome-wide association study summary statistics plasma cerebrospinal fluid (CSF) further replicated in external validation. Bidirectional MR,...

10.1097/md.0000000000041439 article EN cc-by-nc Medicine 2025-02-14

This paper presents a novel multidirectional weighted interpolation algorithm for color filter array interpolation. Our proposed method has two contributions to demosaicking. First, different from conventional methods based on directions or four directions, the exploits greater degree correlations among neighboring pixels along eight improve performance. Second, we propose an efficient postprocessing reduce artifacts difference planes. Compared with state-of-the-art demosaicking algorithms,...

10.1109/tcsvt.2014.2313896 article EN IEEE Transactions on Circuits and Systems for Video Technology 2014-03-26

In this paper, we present a novel color image demosaicking algorithm using voting-based edge direction detection method and directional weighted interpolation method. By introducing the voting strategy, of center missing component can be determined accurately. Along direction, is interpolated gradient by exploring intra-channel correlation neighboring pixels. As compared with latest algorithms, experiments show that proposed provides superior performance in terms both objective subjective qualities.

10.1109/tcsvt.2013.2255421 article EN IEEE Transactions on Circuits and Systems for Video Technology 2013-03-28

Abstract Pain is a common symptom of many diseases with high incidence rate. Clinically, drug treatment, as the main method to relieve pain at present, often accompanied by different degrees adverse reactions. Therefore, it urgent gain profound understanding mechanisms in order develop advantageous analgesic targets. The PD-L1/PD-1 pathway, an important inhibitory molecule immune system, has taken part regulating neuroinflammation and response. Accumulating evidence indicates that pathway...

10.1186/s13578-024-01227-3 article EN cc-by Cell & Bioscience 2024-04-20

This current phase II clinical trial was to compare the effect and safety of adamgammadex, a new cyclodextrin-based selective relaxant binding agent, with sugammadex reverse rocuronium-induced neuromuscular block. Patients were randomised receive adamgammadex (4 or 6 mg kg−1) (2 kg−1, as positive control group) at reappearance second twitch (T2) in response TOF stimulation. The standard data collected. 4 kg−1 (n = 16) 20) adamgammadex- 2 sugammadex-induced recovery time ratio 0.9 2.3, 1.6,...

10.3390/jcm11236951 article EN Journal of Clinical Medicine 2022-11-25

Numerous studies have examined the links between mental disorders such as depression and bipolar disorder, gastrointestinal (GI) diseases. However, few investigated link mood swings GI Given impact of on various conditions growing comprehension gut-brain axis, this study aims to explore their causal relationship using Mendelian randomization (MR) methods.

10.5152/alphapsychiatry.2024.241688 article EN PubMed 2024-08-01

Although diaphragm ultrasound can be used for detecting residual neuromuscular blockade post-surgery, there exists notable dearth in contemporary research exploring the correlation between preoperative Child-Pugh classification and effectiveness of sugammadex reversing rocuronium-induced as evaluated by diaphragmatic ultrasonography. This was a prospective, double-blind, non-randomized controlled clinical trial conducted on patients scheduled laparoscopic liver resection surgery. The...

10.3389/fmed.2024.1370021 article EN cc-by Frontiers in Medicine 2024-04-05

This study aimed to investigate the potential reduction of cardiovascular stress response caused by suspension laryngoscopic surgery through application lidocaine spray on larynx and trachea.

10.1016/j.bjorl.2024.101481 article EN cc-by Brazilian Journal of Otorhinolaryngology 2024-08-05

Desflurane is a new volatile inhalation anesthetic that widely used in medical operation. However, various diseases can be caused by chronic exposure to desflurane, which also greenhouse gas. Therefore, it urgent find suitable method for monitoring desflurane. In this paper, the process of doping Pd, Pt, and Ni on MoS2 surface simulated determine stability structure based first-principles. The adsorption properties sensing Pd-MoS2, Pt-MoS2, Ni-MoS2 desflurane are explored parameters...

10.1021/acsomega.4c05159 article EN cc-by-nc-nd ACS Omega 2024-08-15

The patient is an elderly female, 81 years old. On September 24, 2022, he was admitted to the hospital for "blurred vision in his right eye, photophobia and tears more than 1 year". complained that had undergone phacoemulsification resection intraocular lens implantation of cataract eye a Liling City 2020 due blurred both eyes 3 , reduced after surgery. Now which progressively worsening decreasing, came our treatment.

10.18686/mhr.v2i2.4121 article EN Medical and health research. 2024-06-20
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