A5100647087- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Neonatal and fetal brain pathology
- Pharmacological Effects and Toxicity Studies
- Neuroscience and Neuropharmacology Research
- Circadian rhythm and melatonin
- Vascular Malformations Diagnosis and Treatment
- Chronic Disease Management Strategies
- Dementia and Cognitive Impairment Research
- Esophageal and GI Pathology
- Neuroscience of respiration and sleep
- Radiomics and Machine Learning in Medical Imaging
- Schizophrenia research and treatment
- Cardiac Valve Diseases and Treatments
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Climate Change and Health Impacts
- Cerebrospinal fluid and hydrocephalus
- Gastroesophageal reflux and treatments
- Brain Tumor Detection and Classification
- Colorectal Cancer Screening and Detection
- Cancer Risks and Factors
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Global Cancer Incidence and Screening
Capital Medical University
2020-2024
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
2023
University of Electronic Science and Technology of China
2023
Zhejiang University
2020-2022
Second Affiliated Hospital of Xi'an Jiaotong University
2022
Yale University
2015-2021
Sichuan University
2010-2016
West China Hospital of Sichuan University
2010-2016
Abstract Background The epidemiology of esophageal cancer (EC) can elucidate its causes and risk factors help develop prevention strategies. We aimed to provide an overview the burden, trends, EC in China from 1990 2017. also investigated differences between China, Japan, South Korea discussed possible disparities. Methods used Global Burden Disease Study 2017 obtain data on incident cases, deaths, disability-adjusted life-year (DALY) age-standardized incidence rate (ASIR), death (ASDR),...
Introduction This study aimed to describe the latest epidemiology of female breast cancer globally, analyze change pattern incidence rates and disease’s association with age, period, birth cohort, subsequently present a forecast incidence. Methods Data for analysis were obtained from Global Burden Disease (GBD) Study 2019 World Population Prospects revision by United Nations (UN). We described age-standardized (ASIRs) 1990 then calculated relative risks period cohort using an...
To evaluate the value of 24-hour video-EEG (VEEG) in assessing recurrence risk after a first unprovoked seizure.Consecutively 134 patients with epileptic seizure were recuited from West China Hospital, Sichuan University, between January 2010 and 2013. All underwent VEEG magnetic resonance imaging (MRI) brain, Each patient had at least 24-month follow up.Seventy-six (56.7%) abnormal VEEG, abnormalities was associated an increased (RR 2.84, 95% CI 1.67-4.82, p<0.001). The overall accumulated...
Summary Evaluation of behavioral impairment during epileptic seizures is critical for medical decision making, including accurate diagnosis, recommendations driving, and presurgical evaluation. We investigated the quality testing inpatient video–electroencephalography ( EEG ) monitoring at an established epilepsy center, introduce a technical innovation that may improve clinical care. retrospectively reviewed video‐ data from 152 in 33 adult or pediatric patients admitted monitoring....
Acute type A aortic dissection (ATAAD) is a life-threatening disease. The understanding of its pathogenesis and treatment approaches remains unclear. In the present work, differentially expressed genes (DEGs) from two ATAAD datasets GSE52093 GSE98770 were filtered. Transcription factor TEAD4 was predicted as key modulator in protein-protein interaction (PPI) network. Weighted correlation network analysis (WGCNA) identified five modules four highly correlated with ATAAD. 71 consensus DEGs...
To explore the factors associated with preoperative epileptic seizure and surgical outcome in patients cerebral gangliolioma (GG).A total of 31 consecutive pathologically confirmed ganglioglioma surgically treated from January 2003 to June 2011 West China Hospital Sichuan University were retrospectively reviewed. Clinical data, procedure follow-up information collected analyzed.Nineteen presented seizure, which 63.2% males. The mean age at epilepsy surgery duration 25.6 years 2.3...
Abstract Aim This study aimed to describe the circadian characteristics of hospitalized mortality in order provide nursing guidance for preventing in‐hospital mortality. Design A retrospective analysis on inpatient information was implemented. Methods Harmonic Analysis Time Series applied quantify periodic structure frequency occurrence death. Results total 3300 cases were included present (male, 63.4% and median age 73 years), including 1540 (46.7%) ICU patients. Incidence overall death...
To explore the factors associated with preoperative and postoperative epileptic seizure in patients cavernous malformations (CMs).A total of 52 consecutive from January 2009 to June 2011 who underwent surgical treatment West China Hospital Sichuan University due CMs confirmed by histopathology were retrospectively reviewed.Patients divided into two groups (epilepsy-group non-epilepsy group) according clinical presentation. Other data, procedure, follow-up information collected. Engel...
People with epilepsy face serious driving restrictions, determined using retrospective studies. To relate seizure characteristics to impairment, we aimed study behavior during seizures a simulator. Patients in the Yale New Haven Hospital undergoing video-electroencephalographic monitoring used laptop-based simulator ictal events. Driving function was evaluated by video review and analyzed relation type, impairment of consciousness/responsiveness, or motor seizures. Fifty-one 30 patients were...
Na+/H+ exchanger regulatory factor 1 (NHERF1) is an important scaffold protein participates in the modulation of a variety intracellular signal pathways. NHERF1 was able to enhance effects chemo-drugs breast and cervical cancer cells. Anaplastic lymphoma kinase (ALK) fusion mutations are validated molecules targeted therapy lung cancers, where crizotinib can be used as specific inhibitor suppress tumor progression. However, due less frequent occurrence ALK complexity for factors determine...
Biomarkers are not only of significant importance for cancer diagnosis and selection treatment plans but also recently increasingly used the evaluation malignancy development tumor heterogeneity. Large-size tumors from clinical patients can be unique valuable sources study progression, particularly to extent intratumoral In present study, we obtained a series post-surgery puncture samples breast patient with 4 × 3.5 2 cm in its original size. Immunohistochemistry Ki-67, COX-2, CA IX was...
Objective: Epilepsy is a neurological disorder that causes repeated seizures. Because electroencephalogram (EEG) patterns differ in different states (inter-ictal, pre-ictal, and ictal), seizures can be detected predicted by machine or deep learning. However, studies of brain connectivity features are scarce this field. Our goal to propose method based on for automatic seizure detection prediction.Methods: Two window lengths (1 s 8 s) were employed EEG data segmentation. Five physiological...