A5101702276- Plant Virus Research Studies
- Plant and Fungal Interactions Research
- Plant Disease Management Techniques
- Congenital limb and hand anomalies
- Tumors and Oncological Cases
- Plant Disease Resistance and Genetics
- Nerve injury and regeneration
- Neurogenetic and Muscular Disorders Research
- Foot and Ankle Surgery
- Orthopedic Surgery and Rehabilitation
- Insect symbiosis and bacterial influences
- Insect-Plant Interactions and Control
- Advanced Technologies and Applied Computing
- Advanced Glycation End Products research
- Biochemical and Molecular Research
- Genomic variations and chromosomal abnormalities
- Tendon Structure and Treatment
- Peripheral Nerve Disorders
- Dupuytren's Contracture and Treatments
- Cocoa and Sweet Potato Agronomy
- Fibroblast Growth Factor Research
- Phytoplasmas and Hemiptera pathogens
- Machine Learning in Materials Science
- Chromatin Remodeling and Cancer
- Vascular Malformations and Hemangiomas
Beijing Friendship Hospital
2024
Capital Medical University
2023-2024
Northwest A&F University
2014-2023
Beijing Jishuitan Hospital
2014-2023
Peking University
2014-2023
Agriculture and Forestry University
2023
Weatherford College
2021
Naval Medical Research Command
1996
Uniformed Services University of the Health Sciences
1996
MdMYB88 and MdMYB124 have been demonstrated to be responsible for lignin accumulation in apple under drought stress. In this study, using a metabolomic approach, we identified differentially accumulated phenylpropanoid flavonoid metabolites MdMYB88/124 transgenic RNAi plants control long-term stress conditions roots. We confirmed the regulation of phenylalanine by via UPLC-MS roots both conditions. Using Electrophoretic Mobility Shift Assay (EMSA) ChIP-quantitative PCR (qPCR) analyses, found...
Significance Unlike other eukaryotic viruses, fungal viruses generally lack an extracellular phase in their life cycle. It thus remains unclear whether can spread beyond native hosts. Herein, we investigated the infectivity of a virus, Cryphonectria hypovirus 1 (CHV1) Nicotiana tabacum plants. CHV1 is able to systemically infect plants after mechanical coinoculations with plant such as tobacco mosaic virus (TMV) or when inoculated transgenic expressing TMV movement protein. In inoculation...
Summary Phytoplasmas are insect‐transmitted phytopathogenic bacteria, which secrete effector proteins that often responsible for altering the plant morphology and behaviours of their vectors. Phytoplasma multifunctional TENGU SAP11 induce typical witches’ broom symptoms, but mode action remains unknown. Previously, we have identified a SAP11‐like from wheat blue dwarf phytoplasma, SWP1, induces symptoms in Nicotiana benthamiana . In this study, observed SWP1 ‐expressing transgenic...
Mycoviruses are wide spread throughout almost all groups of fungi but only a small number mycoviruses can attenuate the growth and virulence their fungal hosts. Alternaria alternata is an ascomycete fungus that causes leaf spot diseases on various crop plants. In this study, we identified novel ssRNA mycovirus infecting f. sp. mali strain isolated from apple orchard in China. Sequence analyses revealed virus related to hypoviruses, particular Wuhan insect 14, unclassified hypovirus...
Viroids are pathogenic agents that have a small, circular noncoding RNA genome. They been found only in plant species; therefore, their infectivity and pathogenicity other organisms remain largely unexplored. In this study, we investigate whether viroids can replicate induce symptoms filamentous fungi. Seven representing viroid groups either the nucleus or chloroplast of cells were inoculated to three fungi,
Mycovirus infection has been widely shown to attenuate the virulence of phytopathogenic fungi. Valsa mali is an agriculturally important fungus that causes canker disease in apple trees. In this study, two unrelated mycoviruses [ Cryphonectria hypovirus 1 (CHV1, genus Hypovirus , and single-stranded RNA) Mycoreovirus (MyRV1, double-stranded RNA)] originated from parasitica (chestnut blight fungus) were singly or doubly introduced into V. via protoplast fusion. CHV1 MyRV1 stably infected...
Carbamoyl phosphate synthetase 1 (CPS1) deficiency (OMIM 237300), an autosomal recessive rare and severe urea cycle disorder, is associated with hyperammonemia high mortality. Herein we present 12 genetic variants identified in seven clinically well-characterized Chinese patients CPS1 who were admitted to the Children's Medical Center of Peking University First Hospital from September 2014 August 2023. Seven (two male five female including two sisters) experienced symptoms onset between 2...
A new nerve matrix membrane derived from decellularized porcine nerves has been shown to retain the major extracellular components, and be effective in preventing adhesion between anastomosis sites surrounding tissues a rat sciatic transection model, thereby enhancing regeneration of nerve. The effectiveness may attributed its various bioactive components. In this prospective, randomized, single-blind, parallel-controlled multicenter clinical trial, we compared safety efficacy with...
Objective To evaluate the treatment effects of coronal fracture hamate with fixation titanium miniplate crossing carpometacarpal joint. Methods From December 2011 to June 2015, 17 patients suffered from were treated joint. The all males, aged 18 43 years, average (28.9±7.0) years. According classification Ebraheim’s body fracture, 2 cases type A, 5 B, 10 C. All fractures exposed by dorsal approach. After reduction, fixed joint dorsally. disabilities arm, shoulder and hand (DASH),...
Objective To analyze the morphologic characteristics of first web space in thumb duplication based on Wassel classifications, and propose corresponding treatment strategies. Methods Sixty patients (68 thumbs) were operated between February June 2016. The special vernier caliper goniometer used for hand function assessment to measure distance, intermetacarpal distance (IMD) angle (DIMA) second metacarpal. Paired t test was compare differences these parameters normal side. Emphasis...
Objective To study the results of several operative methods (neurolysis,nerve repair and nerve grafting) for treatment ligated peripheral nerves using rat models.Methods A total 144 rats were randomly assigned to 3 groups:neurolysis group,nerve group grafting group.Ligation sciatic was done first in all animals establish injury model.After 2 weeks,a second surgery carried out treat lesion.Neurolysis,nerve or according assignment.The sacrificed at postoperative week 1,2,4,6,8,10 12...
We proposed a modification of the Rotterdam classification for thumb triplication and tetraplication. Twenty-one patients were included (24 cases four tetraplication). These analysed classified according to involving three steps; from radial ulnar side, we first identified each on radiographs gross appearance divide into or Second, define levels duplication established nomenclature. Third, aberrant features their location assigned thumb, again side. A surgical algorithm was also proposed....
Abstract In this study, we report the complete genome sequence of a novel toti-like virus, tentatively named Rhizopus stolonifer virus 1 (RsTV1), identified from phytopathogenic fungal agent apple fruit rot disease, strain A2-1. RsTV1 had double-stranded RNA genome. The was 5178 nucleotides (nt) in length and contained two open reading frames (ORFs) encoding putative coat protein (CP) RNA-dependent polymerase (RdRp). Phylogenetic analyses based on RdRp CP amino acid sequences revealed that...
Congenital muscular hypertrophy is a rare overgrowth disorder in the phosphatidylinositol-3-kinase related spectrum. In past 3 years, ten patients with 11 limbs involved were treated our centre. The aim of study was to describe clinical and radiological deformities these patients. We documented characteristic morphological changes, such as hypertrophy, loss wrist flexion, thumb hyperabduction, finger deviation skin crease changes palm. Radiologically, mean first metacarpal radial angle...
Objective To present a new classification of polydactyly the foot, axial classification, in order to guide clinical treatment and evaluate prognosis. Methods Retrospective study was conducted on 55 cases with 78 feet treated our hospital from January 2009 December 2014. The number adverse events four aspects foot pain, appearance, function wearing shoes collected by email, telephone or interview. Axial Venn-Watson were used classify advantages disadvantages two classifications...
Objective To investigate the value of muscle redistribution technique (MRT) in recognition human motion intention by intelligent bionic hand. Methods From December 2016 and April 2017, 3 patients with upper limb amputation were treated MRT procedure. The levels located at distal 1/3 forearm, midcarpal joint carpometacarpal joint. In MRT, 4 to 6 muscles tendons stump transferred anchored different areas skin. When actively contracted, tendon pulled skin resulting obvious deformation...