- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiomyopathy and Myosin Studies
- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Immunodeficiency and Autoimmune Disorders
- Cardiovascular Effects of Exercise
- Cardiovascular Health and Disease Prevention
- Antiplatelet Therapy and Cardiovascular Diseases
- Advanced MRI Techniques and Applications
- Mechanical Circulatory Support Devices
- Cardiac Valve Diseases and Treatments
- Blood Pressure and Hypertension Studies
- Vascular anomalies and interventions
- ECG Monitoring and Analysis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Heart Rate Variability and Autonomic Control
- Coronary Interventions and Diagnostics
- Heparin-Induced Thrombocytopenia and Thrombosis
- Sarcoidosis and Beryllium Toxicity Research
- Analytical Methods in Pharmaceuticals
- Inflammasome and immune disorders
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2012-2025
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2013-2024
Ospedale Maggiore
2015-2024
Metropolitana Milanese (Italy)
2024
Policlinico S.Orsola-Malpighi
2022
University of Milano-Bicocca
2013-2014
Ospedale San Pietro Fatebenefratelli
2011
University of Bergamo
2011
ABSTRACT Background The need for transvenous lead extraction (TLE) is increasing worldwide. Since the course of subclavian vein until junction with superior vena cava a frequent place adherences, we aim to assess safety and efficacy short 13Fr bidirectional rotational mechanical sheath as first choice. Methods Results In this multicentric study, 202 carriers cardiac implantable electronic device (CIED) undergoing TLE using 13 Fr were prospectively enrolled. All procedures performed stepwise...
wide antral pulmonary vein isolation (PVI) is effective for treating paroxysmal atrial fibrillation (PAF), although time-demanding. We investigated the impact of a standardized ablation protocol by using bidirectional transeptal steerable sheath, high-density mapping and very high-power-short-duration (vHPSD) catheters on procedure timing, efficacy, safety. consecutive PAF patients free from previous ablations undergoing PVI alone between January 2022 March 2023 were prospectively enrolled....
BACKGROUND: The safety of subcutaneous implantable cardioverter defibrillator (S-ICD) recipients who lead active lifestyles and engage in recreational sports is unknown. We aimed to evaluate the association between lifestyle occurrence arrhythmia- device-related complications, appropriate inappropriate shocks S-ICD recipients. METHODS: assessed a cohort young-adult (15–65 years) patients, evaluated their physical activity with IPAQ (International Physical Activity Questionnaire), on shocks....
Abstract Background Left ventricular assist device (L‐VAD) implantation is increasingly used in patients with heart failure (HF) and most also have an implantable cardioverter defibrillator (ICD). Limited data are available on the incidence of ICD therapies complications this special setting. The aim study was to analyze real‐world predictors therapies, interactions between L‐VAD. Methods We conducted a multicenter retrospective observational advanced HF implanted continuous‐flow L‐VAD,...
Background Atrioventricular block (AVB) is a frequent complication in patients undergoing transcatheter aortic valve implantation (TAVI). Right apex ventricular pacing (RVP) represents the standard treatment but may induce cardiomyopathy over long term. Left bundle branch area (LBBAP) promising alternative, minimizing risk of desynchrony. However, available evidence with LBBAP after TAVI still low. Objective To assess feasibility and safety for AVB post-TAVI compared RVP. Methods Consecutive...
Diabetes mellitus is characterized by structural and functional alterations of the large- medium-size arteries. Whether blood glucose variability, i.e. glycemic oscillations occurring during 24-h period, represents a risk factor for vascular additional to independent on HbA1c in type 1 diabetes still undefined. The present study was carried out with aim at investigating impact different measures variability arterial structure function. We studied 17 non-complicated diabetic patients (11...
Interest in the role of atrial substrate maintaining Atrial Fibrillation (AF) is growing. Fibrosis culprit electrical derangement myocytes. Many cardiovascular risk factors are known to be linked scarring; among them Uric Acid (UA) emerging. The purpose our study find whether UA associated with Left Atrium (LA) pathological substrate.81 patients who underwent radiofrequency transcatheter ablation for nonvalvular AF at cardiological department Niguarda Hospital were enrolled an observational,...
Cardiac magnetic resonance (CMR) has gained a central role in the diagnosis of cardiac amyloidosis (CA). While diagnostic typical late gadolinium enhancement (LGE) pattern (global subendocardial coupled with accelerated contrast washout) been identified, evidence is still conflicting regarding prognostic such examination.We retrospectively analysed all patients referring for CMR at Niguarda Hospital (Milan, Italy) from January 2006 to 2015 suspected CA. Primary outcome was all-cause...
Key Clinical Message A 46‐year‐old woman with congenitally corrected transposition of the great arteries (ccTGA) associated dextrocardia, situs viscerus inversus, and left superior vena cava persistence presented an incessant supraventricular tachycardia. Electrophysiological study was not conclusive in differential diagnosis atrial tachycardia versus atypical atrioventricular (AV) nodal reentrant tachycardia, also due to unconventional anatomy coronary sinus. By a comprehensive mapping...
Abstract
Background Late gadolinium enhancement (LGE) assessed with cardiovascular magnetic resonance (CMR) correlates ventricular arrhythmias and survival in patients structural heart disease. Whether some LGE characteristics may specifically improve prediction of arrhythmic outcomes is unknown. Hypothesis We sought to evaluate scar CMR predict implantable cardioverter‐defibrillator (ICD) interventions dilated cardiomyopathy different etiology. Methods 96 consecutive evaluated received an ICD....
Background: Elderly patients are at high risk of both ischaemic and bleeding events, the low body weight is considered a factor for major in atrial fibrillation (AF) on anticoagulation therapy. The aim our study was to compare safety effectiveness non-vitamin K antagonist oral anticoagulants (NOACs) versus well-controlled vitamin-K antagonists (VKA) therapy among AF aged >75 years with <60 kg prospective registry setting. Methods: Data this were sourced from Italian cohorts PREFER...
The brain and heart are strictly linked the electrical physiologies of these organs share common pathways genes. Epilepsy patients have a higher prevalence electrocardiogram (ECG) abnormalities compared to healthy people. Furthermore, relationship between epilepsy, genetic arrhythmic diseases sudden death is well known. association epilepsy myocardial channelopathies, although already proposed, has not yet been fully demonstrated. aim this prospective observational study assess role ECG...