A5100450273- Sarcoma Diagnosis and Treatment
- Urologic and reproductive health conditions
- Kidney Stones and Urolithiasis Treatments
- Vascular Tumors and Angiosarcomas
- Infant Nutrition and Health
- Cardiac tumors and thrombi
- Cancer-related molecular mechanisms research
- Pediatric Urology and Nephrology Studies
- Clinical Nutrition and Gastroenterology
- Intracerebral and Subarachnoid Hemorrhage Research
- Neuroblastoma Research and Treatments
- Gut microbiota and health
- Tea Polyphenols and Effects
- Hormonal and reproductive studies
- Biochemical Analysis and Sensing Techniques
- Urinary Bladder and Prostate Research
- Molecular Biology Techniques and Applications
- Soft tissue tumor case studies
- Gallbladder and Bile Duct Disorders
- Nutritional Studies and Diet
- Selenium in Biological Systems
- Ear and Head Tumors
- Genital Health and Disease
- Liver Diseases and Immunity
- Ureteral procedures and complications
Peking University
2019-2025
Peking University International Hospital
2019-2025
Guangxi Medical University
2022-2025
Shanghai Ninth People's Hospital
2022-2024
Shanghai Jiao Tong University
2022-2024
Beijing Friendship Hospital
2024
Capital Medical University
2024
Foshan Maternity and Child Health Care Hospital
2024
Tianjin Medical University General Hospital
2021-2023
Shenzhen Maternity and Child Healthcare Hospital
2023
To investigate the effect of epigallocatechin gallate (EGCG) on structural changes gut microbiota in colorectal carcinogenesis.
Retroperitoneal liposarcoma (RPLS) is a critical malignant disease with various clinical outcomes. However, the molecular heterogeneity of RPLS was poorly elucidated, and few biomarkers were proposed to monitor its progression.RNA sequencing performed on training cohort 88 patients identify dysregulated genes pathways using clusterprofiler. The GSVA algorithm utilized assess signaling levels in each sample, unsupervised clustering employed distinguish subtypes. Differentially expressed...
Retroperitoneal liposarcoma (RPLS) is a critical malignant disease with various clinical outcomes. However, the molecular heterogeneity of RPLS was poorly elucidated, and few biomarkers were proposed to monitor its progression.RNA sequencing performed on training cohort 88 patients identify dysregulated genes pathways using clusterprofiler. The GSVA algorithm utilized assess signaling levels in each sample, unsupervised clustering employed distinguish subtypes. Differentially expressed...
<title>Abstract</title> <bold>Background </bold>Angiomatoid fibrous histiocytoma (AFH) is a rare low-grade neoplasm, typically arising in pediatric/adolescent extremity subcutaneous tissues. Adrenal AFH extremely uncommon, with limited reported cases. Elucidating clinicopathologic/molecular profiles of adrenal critical for accurate diagnosis and management. <bold>Case presentation </bold>Two cases (18-year-old male, 50-year-old female) from Guangxi Medical University Second Hospital were...
Serotonin (5-HT) plays pivotal roles in the pathogenesis of postinfectious irritable bowel syndrome (PI-IBS), and luminal 5-HT time-dependently modulates visceral nociception. We found that duodenal biopsies from PI-IBS patients exhibited increased decreased anandamide levels was associated with abdominal pain severity, indicating a link between endocannabinoid signaling pathways PI-IBS. To understand this, we investigated role endocannabinoids modulation nociception rat model. Acute...
Surgery is the primary treatment for skin tumors, but it can result in scarring and distress patients. Developing alternative therapeutic methods necessitates suitable <i>in vitro</i> models, which are currently limited accurately representing vivo</i> cell types microenvironment of tumors. Here, we present a practical approach creating patient-derived tumor organoids that effectively replicate histological characteristics mutational profiles observed clinical tissues. Utilizing single-cell...
Vitamin E was previously reported to reduce calcium oxalate (CaOx) crystal formation. This study explored whether vitamin deficiency affects intrarenal oxidative stress and accelerates deposition in hyperoxaluria. The control (C) group of rats received a standard diet drinking water, while the experimental groups 0.75% ethylene glycol (EG) water for 42 days. Of latter, one (EG group), low-vitamin (LE) (EG+LE last an LE with supplement (4 mg) (EG+LE+E group). C+LE C+LE+E were specific...
Abstract Background Dermatofibrosarcoma protuberans (DFSP) has a high recurrence rate after resection. Because of the lack specific manifestations, recurrent DFSP is easily misdiagnosed as post-resection scar. A few series have reported ultrasound findings DFSP; moreover, usefulness contrast-enhanced in differentiating not been studied. Objective We investigated conventional and differential diagnosis Methods retrospectively evaluated 34 cases 38 postoperative scars examined between January...
AIM:To observe the protective effect of glucagon-like peptide-2 (GLP-2) on intestinal barrier rats with obstructive jaundice and determine possible mechanisms action involved in effect. METHODS:Thirty-six Sprague-Dawley were randomly divided into a sham operation group, an GLP-2 group; each group consisted 12 rats.The was treated after day surgery, whereas other two groups same concentration normal saline.Alanine aminotransferase (ALT), total bilirubin, endotoxin levels recorded at 1, 3, 7,...
As nontraditional model organisms with extreme physiological and morphological phenotypes, snakes are believed to possess an inferior taste system. However, the bitter sensation is essential distinguish nutritious poisonous food resources genomic evidence of in largely scarce. To explore genetic basis characterize evolution receptor genes ( Tas2r s) reptiles, we identified 19 genomes (species) corresponding three orders non-avian reptiles. Our results indicated contractions gene repertoires...
ABSTRACT Background Retroperitoneal liposarcoma (RPLS) is a critical malignant disease with various clinical outcomes. However, the molecular heterogeneity of RPLS was poorly elucidated, and few biomarkers were proposed to monitor its progression. Methods RNA sequencing performed on training cohort 88 patients identify dysregulated genes pathways using clusterprofiler. The GSVA algorithm utilized assess signaling levels in each sample, unsupervised clustering employed distinguish subtypes....
Complete resection (CR) serves as the standard of surgical treatment for retroperitoneal liposarcoma (RPLS). Unfortunately, even at referral centers, recurrence rates are high, and CR may not address multifocal diseases, which a common phenomenon in RPLS. We sought to retrospectively compare clinical outcomes RPLS patients treated with total (ipsilateral) lipectomy (TRL) CR. Because TRL remove potentially tumors fat, have better prognosis than CR.Patients primary/first-recurrent who had been...
Objective: The Transatlantic Australasian Retroperitoneal Sarcoma Working Group conducted a retrospective study on the disease course and clinical management of ganglioneuromas. Background: Ganglioneuromas are rare tumors derived from neural crest cells. Data these remain limited to case reports single-institution series. Methods: Patients all ages with pathologically confirmed primary retroperitoneal, intra-abdominal, pelvic ganglioneuromas between January 1, 2000, 2020, were included. We...
Abstract Background Polyethylene glycol solution (PEG) is widely used for bowel preparation prior to colonoscopies. However, patients often exhibited adverse events as nausea, vomit and distention due its uncomfortable tastes potential side affects. This study aimed evaluate the effectiveness safety of concomitant use green tea (GT) with PEG in colonoscopy. Methods was a prospective, randomized controlled study. It conducted at an outpatient setting colorectal surgery tertiary hospital....
To determine whether specific clinical and radiographic factors predispose arteriovenous malformations (AVMs) presenting with seizure to predict the risk for individual AVM patients.Clinical features cerebral angiograms of consecutive 45 unruptured patients who were diagnosed in our center a 2-year period reviewed. Patient data (analysis cohort) was used construct epileptogenic groups. These groups tested second half patient (test cohort).Among AVMs (47.9%), initial seizures occurred 20...