A5046586779- Asthma and respiratory diseases
- Orthopedic Surgery and Rehabilitation
- Peripheral Nerve Disorders
- Musculoskeletal pain and rehabilitation
- Respiratory and Cough-Related Research
- COVID-19 Clinical Research Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Eosinophilic Esophagitis
- Nerve Injury and Rehabilitation
- Pediatric health and respiratory diseases
- Shoulder Injury and Treatment
- Spine and Intervertebral Disc Pathology
- Inhalation and Respiratory Drug Delivery
- Pharmacological Receptor Mechanisms and Effects
- Trauma Management and Diagnosis
- Pneumothorax, Barotrauma, Emphysema
- Eosinophilic Disorders and Syndromes
- Long-Term Effects of COVID-19
- Tendon Structure and Treatment
- SARS-CoV-2 and COVID-19 Research
- Musculoskeletal Disorders and Rehabilitation
- Shoulder and Clavicle Injuries
- Bone fractures and treatments
- Pneumonia and Respiratory Infections
- Obstructive Sleep Apnea Research
University of Oxford
2021-2024
Oxford BioMedica (United Kingdom)
2021-2024
John Radcliffe Hospital
2021-2024
National Institute for Health Research
2022-2023
The University of Texas at Austin
2022
University Hospital Llandough
2020-2021
Cardiff University
2021
University Hospital of Wales
2020
Miami Hand Center
1998-2019
Drury University
2018
Introduction Pneumothorax and pneumomediastinum have both been noted to complicate cases of coronavirus disease 2019 (COVID-19) requiring hospital admission. We report the largest case series yet described patients with these pathologies (including nonventilated patients). Methods Cases were collected retrospectively from UK hospitals inclusion criteria limited a diagnosis COVID-19 presence either pneumothorax or pneumomediastinum. Patients included in study presented between March June...
Reduction of the risk asthma attacks is a major goal current management. We propose to derive scale predicting based on blood eosinophil count and exhaled nitric oxide (FeNO). Biomarker-stratified trial-level attack rates were extracted pooled from control arms Novel START, CAPTAIN, QUEST, Benralizumab Phase 2b, PATHWAY, STRATOS 1-2 DREAM trials (n=3051). These used rate ratios predicted for different patient groups. The resultant prototype shows potential predict attacks, which may be...
Background There is an emerging understanding that coronavirus disease 2019 (COVID-19) associated with increased incidence of pneumomediastinum (PTM). We aimed to determine its among patients hospitalised COVID-19 in the UK and describe factors outcome. Methods A structured survey PTM was conducted from September 2020 February 2021. UK-wide participation solicited via respiratory research networks. Identified had severe acute syndrome 2 (SARS-CoV-2) infection radiologically proven PTM. The...
The large number of reconstructive procedures in the treatment ACL reflect a lack consistent clinical success, thus creating current controversy over injuries. purpose this study on relationship femoral attachment site to isometric tracking graft was three-fold: 1) develop method for evaluating attach ment ideal pattern; 2) reference table comparing sites excursion; and 3) apply information surgical procedure allow step wise refinement improved results. To aid graphic representation, were...
Hintergrund: Exazerbationen von Asthma und chronisch-obstruktiver Lungenerkrankung (COPD) sind wichtige Ereignisse, die mit kritischen Erkrankungen einhergehen. Die eosinophile Entzündung ist ein behandelbares Symptom, das häufig bei akuten COPD auftritt. Wir stellten Hypothese auf, dass Patienten eosinophilen eine einmalige Injektion Benralizumab, einem humanisierten monoklonalen Antikörper, der gegen den Interleukin-5-Rezeptor alpha gerichtet ist, allein oder in Kombination Prednisolon...
Cumulative trauma disorders account for 56% of all occupational injuries. Currently, injuries affect 15% to 20% Americans. The United States government predicts that by the year 2000, 50% American workforce will have annually and 50 cents every dollar be spent on cumulative disorders. There is common agreement need reduction in workplace. However, there little appropriate definition musculoskeletal pain occurs workplace, or ergonomic epidemiologic model disorders, specific exposure...
Background: The QuickDASH, an abbreviated form of the Disabilities Arm, Shoulder and Hand Questionnaire, uses a graded-adjectives ordinal measurement response scale. In order to improve sensitivity measure make it compatible with widely used measures pain disability, visual analog scale version was developed. present study investigated reliability new over time when for evaluation patients undergoing treatment. Methods: A test-retest model two-day interval evaluate sample thirty-eight...
Diagnostic screening tests for carpal tunnel syndrome (CTS) have not been rigorously assessed in large populations.This study is a cross-sectional analysis from prospective cohort study. Participants' (n = 1,194) symptoms and disease prevalence were measured. Sensitivity, specificity, positive negative predictive values (NPVs) calculated.When defining CTS as tingling/numbness at least two median nerve-served digits an abnormal nerve conduction study, the was 8.9%. The sensitivity of...
Abstract Background Azithromycin is an orally active synthetic macrolide antibiotic with a wide range of anti-bacterial, anti-inflammatory and antiviral properties. It safe, inexpensive, generic licenced drug available worldwide manufactured to scale potential candidate therapy for pandemic coronavirus disease 2019 (COVID-19). was widely used treat severe SARS-CoV MERS-CoV, but date, no randomised data are in any infections. Other ongoing trials exploring short courses azithromycin either...
In acute severe COVID-19, patients present with lung inflammation and vascular injury, accompanied by an exaggerated cytokine response. this study, our aim was to describe the inflammatory mediator profiles in who were previously hospitalized COVID-19 pneumonitis, months after their recovery, compare them those recovering from sepsis healthy controls.
Asthma attacks are a common and important problem. Someone experiences an asthma attack in the United Kingdom every 10 seconds. cause coughing, wheezing, breathlessness, chest tightness highly stressful for patients. They result reduced quality of life, with days lost from work or school. treated oral corticosteroids (OCSs), but these have many short- long-term side effects. monoclonal antibodies (mAbs) revolutionized treatment severe by reducing OCS burden over 50%, some people still...
Objective: The American College of Occupational and Environmental Medicine has updated the treatment guidelines in its Elbow Disorders chapter through revision processes begun 2006. This abbreviated version that highlights some evidence recommendations developed. Methods: Comprehensive systematic literature reviews were accomplished with article abstraction, critiquing, grading, table compilation, guideline finalization by a multidisciplinary expert panel extensive peer-review to develop...
American Medical Association, 2011Reviewed by David A. Fetter, MD, FAAOS, FAADEP, CEDIRDiplomate Board of Orthopaedic SurgeryFellow Academy SurgeonsFellow Disability Evaluating PhysiciansCertification in Impairment and Rating - PhysicianThe second edition "Return to Work," one word, is a masterpiece. The authors are be congratulated for their scientific approach topic that at times has nonscientific contributing factors consider.The preface the acknowledges increasing importance...
Background: The QuickDASH, an abbreviated form of the Disabilities Arm, Shoulder and Hand Questionnaire, uses a graded-adjectives ordinal measurement response scale. In order to improve sensitivity measure make it compatible with widely used measures pain disability, visual analog scale version was developed. present study investigated reliability new over time when for evaluation patients undergoing treatment. Methods: A test-retest model two-day interval evaluate sample thirty-eight...