Kristen R. Hoskinson
A5013427772- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Neonatal and fetal brain pathology
- Infant Development and Preterm Care
- Childhood Cancer Survivors' Quality of Life
- Child and Adolescent Psychosocial and Emotional Development
- Long-Term Effects of COVID-19
- Mental Health via Writing
- Topic Modeling
- Maternal Mental Health During Pregnancy and Postpartum
- Advanced MRI Techniques and Applications
- Glioma Diagnosis and Treatment
- Family Support in Illness
- Resilience and Mental Health
- Trauma and Emergency Care Studies
- Congenital Anomalies and Fetal Surgery
- Cognitive Abilities and Testing
- Multisensory perception and integration
- Health, Environment, Cognitive Aging
- Face Recognition and Perception
- Cognitive Science and Mapping
- Spinal Dysraphism and Malformations
Nationwide Children's Hospital
2017-2025
The Ohio State University
2017-2025
Cornell University
2021-2023
Blythedale Children's Hospital
2021-2023
University of Colorado Denver
2021-2023
Children's Hospital Colorado
2021-2023
Johns Hopkins University
2021-2023
Emory University
2023
The Ohio State University Wexner Medical Center
2022
Lundin (Norway)
2022
Pediatric traumatic brain injury (TBI) may affect children's ability to perform everyday tasks (i.e., adaptive functioning). Guided by the American Association for Intellectual and Developmental Disabilities (AAIDD) model, we explored association between TBI functioning at increasing levels of specificity (global, AAIDD domains, subscales). We also examined contributions executive function processing speed as mediators TBI's effects on functioning.Children (ages 8-13) with severe (STBI; n =...
This study aims to evaluate the efficacy of a brief cognitive behavioral intervention program for children and adolescents experiencing persistent post-concussion symptoms. A total 31 patients aged 10 18 years participated in intervention. The median time since injury at treatment onset was 95 days though range large (23–720 days). Treatment on average four sessions duration. Sessions included concussion education, activity scheduling, sleep hygiene relaxation training, restructuring....
An extensive library of symptom inventories has been developed over time to measure clinical symptoms traumatic brain injury (TBI), but this variety led several long-standing issues. Most notably, results drawn from different settings and studies are not comparable. This creates a fundamental problem in TBI diagnostics outcome prediction, namely that it is possible equate distinct tools inventories. Here, we present an approach using semantic textual similarity (STS) link scores across...
Our study addressed aims (1) to test the hypothesis that moderate-severe traumatic brain injury (TBI) in pediatric patients is associated with widespread white matter (WM) disruption, (2) age and sex affect WM organization after injury, (3) examine associations between neurobehavioral outcomes.
This study examined the associations among chronic stress, activation in prefrontal cortex (PFC), executive function, and coping with stress at-risk a comparison sample of adolescents. Adolescents (N = 16; age 12–15) mothers (n 8) without history depression completed questionnaires, neurocognitive testing, functional neuroimaging response to working memory task (N-back). Children depressed demonstrated less anterior PFC (APFC) both greater than controls distinct areas within dorsal cingulate...
To characterize the demographics, clinical course, and predictors of cognitive recovery among children young adults receiving inpatient rehabilitation following pediatric traumatic brain injury (TBI).Retrospective observational, multicenter study.Eight acute facilities in United States with specialized programs for treating patients TBI.Children (0-21 years) TBI (n = 234) rehabilitation.Not applicable.Admission discharge status assessed by WeeFIM Cognitive Developmental Functional Quotient...
Children are at risk for behavioral and adaptive difficulties following pediatric brain tumor. This study explored whether familial/demographic, developmental, diagnostic, or treatment-related variables best predict posttreatment functioning.Participants included 40 children (mean age = 12.76 years, SD 4.01) time since diagnosis 1.99 0.21) Parents rated children's adjustment functioning provided demographic developmental histories. Diagnostic information was abstracted from medical...
Investigators in neuroscience have turned to Big Data address replication and reliability issues by increasing sample sizes, statistical power, representativeness of data. These efforts unveil new questions about integrating data arising from distinct sources instruments. We focus on the most frequently assessed cognitive domain - memory testing demonstrate a process for reliable harmonization across three common measures. aggregated global raw 53 studies totaling N = 10,505 individuals. A...
Abstract Childhood traumatic brain injury (TBI) affects over 600 000 children per year in the United States. Following TBI, are vulnerable to deficits psychosocial adjustment and neurocognition, including social cognition, which persist long-term. They also susceptible direct secondary damage related networks. In this study, we examine whether morphometry of mentalizing network (MN) theory mind (ToM; one component cognition) mediates effects TBI on adjustment. Children with severe (n = 15,...
Aim: This pilot study explored whether childhood stroke impairs performance on theory of mind (ToM) tasks and ToM task correlates with resting state connectivity in brain regions linked social cognition. Method: We performed a case-control 10 children age- gender-matched controls. They completed 2 tasks, was measured functional magnetic resonance imaging (MRI). Results: Children worse than controls conative tasks. Resting the central executive network significantly higher between right left...
The purpose of this study was to determine associations among neurocognitive outcomes and white matter integrity in the inferior fronto-occipital fasciculus (IFOF), uncinate (UF), genu corpus callosum (gCC) survivors pediatric brain tumor healthy controls (HCs). Eleven (ages 8-16; >2 years post-treatment) 14 HCs underwent MRI; diffusion tensor imaging tractography (DSI Studio) used assess integrity. Participants completed neuropsychological assessment overall cognitive ability, executive...
Deficits in memory performance have been linked to a wide range of neurological and neuropsychiatric conditions. While many studies assessed the impacts individual conditions, this study considers broader perspective by evaluating how recall is differentially associated with nine common conditions using data drawn from 55 international studies, aggregating 15,883 unique participants aged 15–90. The effects dementia, mild cognitive impairment, Parkinson’s disease, traumatic brain injury,...
Investigators in neuroscience have turned to Big Data address replication and reliability issues by increasing sample size. These efforts unveil new questions about how integrate data across distinct sources instruments. The goal of this study was link scores common auditory verbal learning tasks (AVLTs). This international secondary analysis aggregated multisite raw for AVLTs 53 studies totaling 10,505 individuals. Using the ComBat-GAM algorithm, we isolated removed component memory...
Traumatic brain injury (TBI) is a major cause of death and disability in children both developed developing nations. Children adolescents suffer from TBI at higher rate than the general population; however, research this population lags behind adults. This may be due, part, to smaller number investigators engaged with also related changes safety laws clinical practice that have altered length hospital stays, treatment, access population. Specific developmental issues warrant attention...
Traumatic brain injury (TBI) is a major cause of morbidity and mortality in children; survivors experience long-term cognitive motor deficits. To date, studies predicting outcome following pediatric TBI have primarily focused on acute behavioral responses proxy measures severity; unsurprisingly, these explain very little the variance heterogenous injury. In adults, certain imaging biomarkers help predict recovery moderate to severe TBI. This multi-center, retrospective study, characterizes...
The current study examines whether psychosocial outcomes following pediatric traumatic brain injury (TBI) vary as a function of children's rejection sensitivity (RS), defined their disposition to be hypersensitive cues from peers.Children ages 8-13 with history severe TBI (STBI, n=16), complicated mild/moderate (n=35), or orthopedic (OI, n=49) completed measures assessing self-esteem and RS on average 3.28 years post-injury (SD=1.33, range=1.25-6.34). Parents reported child's emotional...
To describe dosing practices for amantadine hydrochloride and related adverse effects among children young adults with traumatic brain injury (TBI) admitted to pediatric inpatient rehabilitation units.Eight acute units located throughout the United States comprising Pediatric Brain Injury Consortium.Two-hundred thirty-four aged 2 months 21 years TBI.Retrospective data revie.Demographic variables associated use of amantadine, dose, reported effects.Forty-nine patients (21%) 0.9 20 received...
ABSTRACT: Objective: Adolescents born extremely preterm (EPT, gestational age [GA] <28 weeks) are at higher risk for problems in peer socialization than those full-term (FT, GA >36 weeks). This study was designed to examine the possibility that adolescents EPT may also have difficulty transitioning from parents peers socialization, a process referred as “social reorienting.” A secondary aim investigate associations of social reorienting with other neurodevelopmental characteristics....