Ana Manzanares
A5013907426- Acute Myeloid Leukemia Research
- Magnetic confinement fusion research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Fusion materials and technologies
- Superconducting Materials and Applications
- Laser-Plasma Interactions and Diagnostics
- Nuclear reactor physics and engineering
- Particle accelerators and beam dynamics
- Nuclear Physics and Applications
- Cancer Genomics and Diagnostics
- Infrared Target Detection Methodologies
- High-Energy Particle Collisions Research
- Nuclear Materials and Properties
- Particle Accelerators and Free-Electron Lasers
- Calibration and Measurement Techniques
- Single-cell and spatial transcriptomics
- Image Processing Techniques and Applications
- Chronic Myeloid Leukemia Treatments
- Solar and Space Plasma Dynamics
- Advanced Optical Sensing Technologies
- Infective Endocarditis Diagnosis and Management
- Astronomical Observations and Instrumentation
- Adaptive optics and wavefront sensing
- Ocular and Laser Science Research
- Thermography and Photoacoustic Techniques
Josep Carreras Leukaemia Research Institute
2023-2024
Universitat Autònoma de Barcelona
2021-2024
Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas
2008-2024
Universidad Complutense de Madrid
1997-2024
Institut Català d'Oncologia
2023
Fundación Josep Carreras Contra la Leucemia
2021
Royal Military Academy
2020
University of Missouri–St. Louis
1997
Disruptions are a major operational concern for next generation tokamaks, including ITER.They may generate excessive heat loads on plasma facing components, large electromagnetic forces in the machine structures and several MA of multi-MeV runaway electrons.A more complete understanding processes methods to suppress them is necessary ensure safe reliable operation future tokamaks.Runaway electrons were studied at JET-ILW showing that their dependencies (accelerating electric field, avalanche...
Abstract A series of experiments have been executed at JET to assess the efficacy newly installed shattered pellet injection (SPI) system in mitigating effects disruptions. Issues, important for ITER disruption mitigation system, such as thermal load mitigation, avoidance runaway electron (RE) formation, radiation asymmetries during quench electromagnetic control and RE energy dissipation addressed over a large parameter range. The efficiency has examined various SPI strategies. paper...
Relativistic electron (RE) beams at high current density (low safety factor, qa) yet very low free-electron accessed with D2 secondary injection in the DIII-D and JET tokamak are found to exhibit large-scale MHD instabilities that benignly terminate RE beam. In JET, this technique has enabled termination of MA-level currents without measurable first-wall heating. This scenario thus offers an unexpected alternate pathway achieve mitigation collisional dissipation. Benign is explained by two...
Abstract We present an overview of results from a series L–H transition experiments undertaken at JET since the installation ITER-like-wall (JET-ILW), with beryllium wall tiles and tungsten divertor. Tritium, helium deuterium plasmas have been investigated. Initial in tritium show ohmic transitions low density power threshold for ( P LH ) is lower than ones densities, while we still lack contrasted data to provide scaling high densities. In there notable shift which minimum <?CDATA...
Abstract Alterations in epigenetic marks, such as DNA methylation, represent a hallmark of cancer that has been successfully exploited for therapy myeloid malignancies. Hypomethylating agents (HMA), azacitidine, have become standard-of-care to treat myelodysplastic syndromes (MDS), neoplasms can evolve into acute leukemia. However, our capacity identify who will respond HMAs, and the duration response, remains limited. To shed light on this question, we leveraged unprecedented analytic power...
The new JET ITER-like wall (made of beryllium and tungsten) is more fragile than the former carbon fiber composite requires active protection to prevent excessive heat loads on plasma facing components (PFC). Analog CCD cameras operating in near infrared wavelength are used measure surface temperature PFCs. Region interest (ROI) analysis performed real time maximum measured each ROI sent vessel thermal map. system started October 2011 has already successfully led a safe landing when hot...
Abstract Runaway electrons (REs) created during tokamak disruptions pose a threat to the reliable operation of future larger machines. Experiments using shattered pellet injection (SPI) have been carried out at JET investigate ways prevent their generation or suppress them if avoidance is not sufficient. Avoidance possible SPI contains sufficiently low fraction high-Z material, it fired early in advance disruption prone runaway generation. These results are consistent with previous similar...
The recent installation of a full metal, ITER-like, first wall provided the opportunity to study impact plasma-facing materials on plasma initiation or breakdown. This for time presents experimental characterisation tokamak breakdown at JET, using all discharges since 2008, covering both operations with main chamber carbon and beryllium ITER-like wall. It was found that avalanche phase unaffected by change in material. However, changes out-gassing lower levels resulted better controlled...
Abstract A sequence of fuel recovery methods was tested in JET, equipped with the ITER-like beryllium main chamber wall and tungsten divertor, to reduce plasma deuterium concentration less than 1% preparation for operation tritium. This also a key activity regard refining clean-up strategy be implemented at end 2nd DT campaign JET (DTE2) assess tools that are envisaged mitigate tritium inventory build-up ITER. The began 4 days baking 320 °C, followed by further which Ion Cyclotron Wall...
Abstract Imaging diagnostics in Joint European Torus have become essential the study of plasma wall interactions and protection facing components. During deuterium operations, location these was at close proximity to vessel. However, for 50–50 deuterium-tritium operation, neutron yield impact onto electronics imaging would caused them fail completely locations. Shielding systems from neutrons is achieved by relocating a selected number outside Hall (i.e. other side biological shield wall)....
Abstract The isotope effect, hydrogen (H) versus deuterium (D), on the gross beryllium (Be) erosion yield has been measured in ohmic limiter plasmas JET tokamak by spectroscopic means. A simplified method to extract effective sputtering from quotient of radiances D α or γ and Be II lines at 527 nm was applied. clear effect found, being about a factor 2 larger compared H whole explored plasma density range. This is agreement with physical data obtained + ion beams also material surface...
Abstract A remote viewing system located outside the biological shield wall to image divertor region in JET is presented here. This paper focuses on optical and mechanical designs of installation a line sight which capable imaging over an distance approximately 31 m. In addition, it includes experience obtained during operations demonstrates its successful performance. was second used D-T campaign follows from dedicated wide angle view also compatible with common elements construction two...
The equatorial vis/IR wide angle viewing system is present in four ITER diagnostic ports. This instrument will cover a large field of view with high spatial and temporal resolutions, to provide real time temperature measurements plasma facing components, spectral data the visible range, information on runaway electrons, pellet tracking. needs be reliable, precise, long lasting. Its design driven by both tokamak severe environment performances required for machine protection. preliminary...
This article is a summary of the measurements recently installed wide‐view fast visible camera in Joint European Tokamak JET. Here we limit ourselves to description different phenomena and leave for forthcoming articles more extensive analysis every phenomenon.
Abstract Experiments and modelling have been carried out to optimize the magnetic field null during breakdown at JET. Such optimization may prove be essential for reliable plasma initiation low voltages, e.g. in ITER where value of electric available will limited 0.33 V m −1 . A two-dimensional FEM electromagnetic model has employed predict stray configuration JET breakdown. This includes active poloidal circuits, a description passive structure circuit. In particular, gap top iron circuit...
High speed visible imaging allows to visualize the 2-dimensional dynamics of fast phenomena in boundary layer fusion plasmas. Here we describe two high cameras currently operating JET tokamak, enabling simultaneous observation a large fraction tokamak vacuum vessel with appropriate configuration for many different plasma phenomena. As an example discuss recent observations on spatial and temporal emission at outer wall during Edge Localized Modes (ELMs) penetration Shattered Injected Pellet...
It is well known since the last years that in JET, with ITER-like wall, performance of high-power Hmode plasmas strongly depends on divertor magnetic topology.This generally attributed to effect field shaping neutral flux transport and pumping, which determine high density H-mode pedestal properties finally global confinement.In present work we have analysed for different configurations spatial distribution dynamic behaviour D emission.Experimental observations indicate certain...
The measurement requirements which have been defined for ITER are being associated to specific diagnostics they guidelines the development - not technical specifications. As intermediate step we consider definition of operational specifications and R&D. This is elucidated here example Visible Infrared diagnostic at equatorial plane ITER. given in terms temperature spectral luminance ranges, spatial coverage temporal resolution. take harsh environment, difficulties measurements role into...