- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Cancer-related molecular mechanisms research
- Liver Disease Diagnosis and Treatment
- Peroxisome Proliferator-Activated Receptors
- Bioinformatics and Genomic Networks
- Immune Cell Function and Interaction
- Phytoestrogen effects and research
- Ophthalmology and Eye Disorders
- Female Genital Mutilation/Cutting Issues
- Endoplasmic Reticulum Stress and Disease
- Renal cell carcinoma treatment
- COVID-19 Pandemic Impacts
- Retinopathy of Prematurity Studies
- HIV, TB, and STIs Epidemiology
- Neuroinflammation and Neurodegeneration Mechanisms
- Tryptophan and brain disorders
- Diabetes and associated disorders
- Connexins and lens biology
- Menopause: Health Impacts and Treatments
- Ferroptosis and cancer prognosis
Wuxi Taihu Hospital
2025
Universiti Malaysia Sarawak
2025
Second Affiliated Hospital of Xinjiang Medical University
2023-2024
Xinjiang Medical University
2023-2024
Capital Medical University
2022-2024
Xinjiang Uygur Autonomous Region Uygur Medicine Hospital
2023
Lanzhou University
2021
Sun Yat-sen University
2009-2014
Beijing Center for Disease Prevention and Control
2009
To investigate the incidence of HIV-1, syphilis, hepatitis B virus (HBV), and C (HCV) infections predictors associated with retention in a 12-month follow-up study among men who have sex (MSM) Beijing, China.A total 507 eligible seronegative MSM were enrolled. Study participants tested for HBV, HCV counseled at baseline, 6-month, visits. The rates analyzed as function demographic, behavioral, recruitment variables.Of participants, 86.2% (437) retained cohort visit. 2.6 per 100 person-years...
Congenital cataract (CC) is the primary cause of treatable childhood blindness. Population-based assessments prevalence and surgery age CC, which are critical for improving management strategies, have been unavailable in China until now. We conducted a hospital-based, cross-sectional study hospital charts CC patients younger than 18 years old from January 2005 to December 2010 at Zhongshan Ophthalmic Center (ZOC) Guangzhou, China. Residence, gender, surgery, hospitalization time, presence...
Public health campaigns are essential for promoting vaccination behavior, but factors such as socioeconomic status, geographical location, campaign quality, and service accessibility influence vaccine uptake. In the Wuxi region of China, disparities in behavior seen between urban rural populations among different groups. This study aims to explore related public that affect Wuxi, contributing better strategies. A cross-sectional survey was conducted 750 participants focusing on their...
Male circumcision can reduce the risk of HIV acquisition among heterosexual men, but its effectiveness is uncertain in men who have sex with (MSM). Additionally, acceptability Chinese unknown given a lack history and cultural norms endorsing neonatal adult circumcision. This study evaluated willingness to participate clinical trial 328 MSM. Some 11.6% respondents reported having been circumcised, most them due tight foreskin. Of 284 uncircumcised MSM, 16.9% said they were absolutely willing...
Pneumonia is a common disease worldwide in preschool children. Despite its large population size, China has had no comprehensive study of the national prevalence, risk factors, and management pneumonia among We therefore investigated prevalence children Chinese seven representative cities, explore possible factors on children, with view to calling world's attention childhood reduce pneumonia.Two group samples 63,663 52,812 were recruited from 2011 2019 surveys, respectively. Which derived...
Abstract Objective To investigate the severity and risk factors of menopausal symptoms in middle-aged women Gansu Province China. Methods In this cross-sectional study, a total 7319 (aged 40–55 years) attended health survey China were enrolled. Information on demographics, status, reproductive history, history chronic diseases was collected via structured questionnaire. Severity symptom evaluated by Modified Kupperman Menopausal Index. Ordinal logistic regression model applied to explore its...
Abstract Type 2 diabetes mellitus combined with metabolic dysfunction-associated steatotic liver disease (MASLD) leads to an increasing incidence of injury year by year, and patients are at a significantly higher risk developing cirrhosis or even failure. No drugs have emerged specifically treat this disease. The aim study is investigate the mechanisms causative hub genes type MASLD. data were obtained through GEO platform for bioinformatics analysis validated in vitro experiments find...
We compared changes in morphology and intraocular pressure (IOP) induced by clear 2.2-mm 3.0-mm corneal incisions a cohort of patients with cataracts.In 160 eyes (from 70 men 90 women at the Ophthalmic Center Sun Yat-sen University), optical coherence tomography tonometry were performed 1, 5, 24 hours after cataract surgery. The main outcome measures IOP, postoperative Descemet membrane detachment (DMD), healing surgical incision, inflammation anterior chamber.Five surgery, had lower IOPs (P...
To provide evidence for policy makers human immunodeficiency virus (HIV) prevention and control, we investigated HIV, syphilis, hepatitis C (HCV) infection the availability of methadone maintenance treatment (MMT) among migrant drug users in Beijing.A total 222 participants from 3 main communities where abusers reside were interviewed, completed a questionnaire, screened HIV using enzyme-linked immunosorbent assay, confirmed by Western blot. Descriptive statistics, χ tests, binary logistic...
With the increasing prevalence of diabetes mellitus worldwide, type 2 (T2D) combined with cognitive impairment and aging has become one common important complications mellitus, which seriously affects quality life patients, imposes a heavy burden on patients' families society. Currently, there are no special measures for treatment in mellitus. Therefore, search potential biological markers is great significance future precisive treatment. We downloaded three gene expression datasets from GEO...
Objective To evaluate the changes in antenor segment configuration after peripheral iridectomy (PD or trabeculectomy (Trab) acute primary angle closure glaucoma (APACG). Methods FiRy-seven eyes of 57 patients with APACG were successive collected. PI was performed to those clock hours anterior synechiae (PAS) 6, while Trab PAS >6. Anterior optical coherence tomography (AS-OCT) examination before and 3 months PI/Trab compare central chamber depth (ACD), opening distance (AOD), trabecular iris...
Abstract Objective: Diabetic neuropathy is one of the most common chronic complications and present in approximately 50% diabetic patients. A bioinformatic approach was used to analyze candidate genes involved distal symmetric polyneuropathy their potential mechanisms. Methods: GSE95849 downloaded from Gene Expression Omnibus database (GEO) for differential analysis, together with identified peripheral neuropathy-associated three major metabolism-associated CTD obtain overlapping...
Abstract Background This study explore the possible pathway of MicroRNA-130a, TXNIP, CD44 and TGF-β1 improving liver heart injury in diabetes nephropathy based on bioinformatics ananlysis. Methods Screening Key Genes Using Bioinformatics Analysis. The biochemical index serum levels were detected analyzed by Pearson correlation analysis 100 DN patients 50 healthy controls. rats model randomly divided into two groups. expression morphological changes was detected. Results Analysis...
Abstract Objective Type 2 diabetes combined with non-alcoholic fatty liver disease (NAFLD) rapidly increases the risk of developing cirrhosis or even failure in type diabetes, and no drugs have yet emerged to specifically treat this disease. Therefore, it is urgent find precise targets for pathogenesis NAFLD. Thus, paper uses bioinformatics analyze candidate genes involved NAFLD their potential mechanisms. Methods GSE49541 was downloaded from Gene Expression Omnibus (GEO) database identify...
Objective To compare the difference and repeatability between anterior segment optical coherence tomography (AS-OCT) ultrasound biomicroscope (UBM) in measuring central chamber depth (ACD). Methods Twenty-nine patients (32 attacked eyes 23 unaffected fellow eyes) with acute primary angle closure glaucoma (APACG) 41 (74 chronic (CPACG) were included this study. AS-OCT UBM used to measure ACD of these APACG CPACG subjects. Pair sample t test correlation analysis introduced analyze values 2...
Objective To evaluate the relationship between axial movement and accommodative amplitude of Tetraflex intraocular lens (Lenstec, Inc., St. Petersburg, FL). Methods Prospective case-control study comprised 20 eyes patients with age-related cataract who underwent phacoemulsification performed by a single surgeon, 10 which were implanted IOLs (Tetraflex group) other monofocal limited accommodation capacity (monofocal group). Uncorrected best corrected distance, intermediate near visual acuity,...