A5100776247- Reproductive Biology and Fertility
- Ovarian function and disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Prenatal Screening and Diagnostics
- Reproductive System and Pregnancy
- Pregnancy and Medication Impact
- Spondyloarthritis Studies and Treatments
- Endometriosis Research and Treatment
- Bone and Dental Protein Studies
- dental development and anomalies
- Healthcare Policy and Management
- Ovarian cancer diagnosis and treatment
- Cardiovascular Health and Risk Factors
- Bone Tumor Diagnosis and Treatments
- Parasites and Host Interactions
- Traumatic Brain Injury Research
- HIV Research and Treatment
- Animal Disease Management and Epidemiology
- Hearing, Cochlea, Tinnitus, Genetics
- HIV, Drug Use, Sexual Risk
- Physical Activity and Health
- Pediatric health and respiratory diseases
- Mobile Health and mHealth Applications
- Rheumatoid Arthritis Research and Therapies
- Cassava research and cyanide
Nanjing Maternity and Child Health Care Hospital
2021-2025
Nanjing Medical University
2020-2025
Sichuan University
2024
West China Second University Hospital of Sichuan University
2024
Shaanxi Institute of Zoology
2024
Changzhou No.2 People's Hospital
2020-2024
Women's Hospital
2024
Second Affiliated Hospital of Nanjing Medical University
2021
University of Electronic Science and Technology of China
2021
National Center for Chronic and Noncommunicable Disease Control and Prevention
2010-2019
T cells expressing chimeric antigen receptors, especially CD19 CAR-T have exhibited effective antitumor activities in B cell malignancies, but due to several factors such as escape effects and tumor microenvironment, their curative potential hepatocellular carcinoma has not been encouraging. To reduce the risk of carcinoma, this study was design construct a bispecific CAR targeting c-Met PD-L1. c-Met/PD-L1 were obtained by lentiviral transfection, transfection efficiency monitored flow...
The increasing prevalence of obesity underscores the need to explore its impact on assisted reproductive technology (ART) outcomes. This study aims evaluate association between visceral fat area (VFA), measured by bioelectrical impedance analysis (BIA), and pregnancy outcomes following frozen embryo transfer (FET). In this retrospective clinical study, data 1,510 patients who underwent FET April 2022 2023 were analyzed. VFA was BIA, categorized into low high groups based a threshold 65 cm²....
Dentinogenesis imperfecta (DGI), Shields type-II is an autosomal dominant genetic disease which severely affects the function of patients' teeth. The dentin sialophosphoprotein (DSPP) gene considered to be pathogenic DGI-II. In this study, a DGI-II family with novel DSPP mutation were collected, functional characteristics DGI cells and clinical features analyzed better understand genotype-phenotype relationship disease.Clinical data whole exome sequencing (WES) was conducted, Sanger used...
Purpose This study aimed to investigate the clinical and pathological characteristics, treatment strategies, prognosis of cervical clear cell carcinoma (CCCC) in patients not exposed diethylstilbestrol utero Methods The diagnosed with CCCC at West China Second University Hospital Sichuan between January 2011 Jun 2023 were enrolled for this retrospective study. characteristics information on follow-up collected. Kaplan–Meier method Cox regression analysis performed identify relative variables...
To investigate the impact of antibiotic treatment for chronic endometritis (CE) on pregnancy outcome frozen-thawed embryo transfer (FET) cycles and relevant clinical risk factors associated with CE. A retrospective cohort analysis was conducted 1352 patients who underwent hysteroscopy diagnostic curettage at Nanjing Maternal Child Health Hospital from July 2020 to December 2021. All CD138 immunohistochemical (IHC) testing diagnose CE, a subset them FET after hysteroscopy. Patient histories...
Abstract Background C‐reactive protein (CRP) level is one of the most widely used parameters to assess ankylosing spondylitis (AS), since CRP associated with poor radiographic progression AS patients. Recent studies have investigated association between gene variants and risk, but conflicting findings. Material Methods We enrolled 232 cases 314 controls in this case‐control study. Next, we assessed rs3091244 polymorphism efficacy etanercept for AS. Genotyping was done using a...
Abstract STUDY QUESTION Does unplanned spontaneous follicular growth and ovulation affect clinical outcomes after planned artificial frozen-thawed embryo transfer (AC-FET) cycles? SUMMARY ANSWER AC-FET events resulted in notably better pregnancy with a significantly higher implantation rate (IR), (CPR), ongoing (OPR) live birth (LBR) lower miscarriage rate. WHAT IS KNOWN ALREADY The protocol without GnRH agonist administration is associated low incidence of ovulation. In the literature,...
Abstract Background Embryo aneuploidy is a main of principal reason pregnancy loss, in vitro fertilization (IVF) failure and birth defects offspring. Previous researchs have demonstrated that Y chromosome AZFc microdeletion was associated with reproduction outcomes, however, the relationship between embryo remains unexplored. Methods This retrospective cohort study enrolled 513 patients 603 cycles reproductive center Nanjing Maternity Child Health Care Hospital from January 1, 2016 to June...
OBJECTIVE: To study the preventive strategies through analyzing poisoning cases from National Injury Surveillance System (NISS), 2006 to 2008. METHODS: Data of was descriptively analyzed Chinese NISS, RESULTS: The proportion all injuries NISS were 2.57%, 2.48% and 2.52% 2008, which ranked sixth in causes. Most people being poisoned had junior middle school education most them agriculture/animal husbandry/fishery/water producers or commercial/service personnel. incidents happened at home,...
<title>Abstract</title> <bold>Purpose:</bold> To investigate the impact of antibiotic treatment for chronic endometritis (CE) on pregnancy outcome frozen-thawed embryo transfer (FET) cycles and relevant clinical risk factors associated with CE. <bold>Methods:</bold> A retrospective cohort analysis was conducted 1352 patients who underwent hysteroscopy diagnostic curettage at Nanjing Maternal Child Health Hospital from July 2020 to December 2021. All CD138 immunohistochemical (IHC) testing...
Background: Epidermal growth factor (EGF) is a potent pro-angiogenic molecule promoting the angiogenic phenotype of ankylosing spondylitis (AS).Studies demonstrated that EGF rs3756261 polymorphism was associated with risk inflammatory diseases, but not including AS. Methods: To investigate association between and AS, we genotyped in 208 patients AS 412 controls Chinese Han population using custom-by-design 48-Plex SNP scan TM Kit.The serum levels were measured an enzyme-linked immunosorbent...
Gram-negative bacteria are the main bacterial pathogens infecting Chinese giant salamanders (Andrias davidianus; CGS) in captivity and wild, causing substantial economic losses CGS industry. However, molecular mechanisms underlying pathogenesis following infection remain unclear.
Objective: To quantify the effects of short-term walking intervention on body mass index (BMI), waist circumference, and related indicators working population. Methods: The China Motivational Healthy Walking Program in 2016 recruited 29 224 individuals from 139 demonstration areas for comprehensive prevention control chronic non-communicable diseases at national level 70 provincial level. All subjects volunteered to participate into this program. lasted 100 days June September 2016....
Oxidative stress is one of the important causes abnormal embryonic development, in which reactive oxygen species (ROS) play an role. Embryonic ROS was generated various metabolic processes cells, and level can be affected by different stages development environment around. Physiological work as a second messenger to participate signal transduction. However, excessive may cause mitochondrial damage, DNA lipid peroxidation even cell apoptosis embryo, resulting developmental arrest embryo. This...