A5103097234- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Cardiac Arrhythmias and Treatments
- Geological and Geochemical Analysis
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Coronary Interventions and Diagnostics
- Cardiac pacing and defibrillation studies
- Cardiac Valve Diseases and Treatments
- Advancements in Photolithography Techniques
- earthquake and tectonic studies
- Congenital Heart Disease Studies
- Coronary Artery Anomalies
- Geochemistry and Geologic Mapping
- Nanofabrication and Lithography Techniques
- High-pressure geophysics and materials
- Carbon Dioxide Capture Technologies
- Transplantation: Methods and Outcomes
- Kawasaki Disease and Coronary Complications
- Membrane Separation and Gas Transport
- Lipoproteins and Cardiovascular Health
- Geology and Paleoclimatology Research
- Aortic Disease and Treatment Approaches
- Semiconductor materials and devices
Toshiba (Japan)
2009-2025
Ehime University
2015-2024
Tokyo Women's Medical University
2015-2024
National Museum of Nature and Science
2021
Baylor College of Medicine
2021
Nihon University
2007-2020
Yokohama National University
2004-2020
Graduate School USA
2016-2020
Japan Synchrotron Radiation Research Institute
2020
University of Shiga Prefecture
2020
Background: It has been suggested that intensive lipid-lowering therapy using statins significantly decreases atheromatous plaque volume. The effect of rosuvastatin on volume in patients with stable coronary artery disease (CAD), including those receiving prior therapy, was examined the present study. Methods and Results: A 76-week open-label trial performed at 37 centers Japan. Eligible began treatment 2.5 mg/day, which could be increased 4-week intervals to ≤20 mg/day. total 214 underwent...
Background: The aim of this study was to elucidate the time course atorvastatin-induced changes in vulnerable plaque using angioscopy and intravascular ultrasound (IVUS). Methods Results: Fifty-seven hypercholesterolemic patients with coronary artery disease (CAD) were treated atorvastatin (10-20 mg/day) for 80 weeks then plaques evaluated IVUS. Angioscopic images classified into 6 grades (0-5) based on yellow color intensity. A 20-mm segment containing angioscopically-identified also...
The Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (JAPAN-ACS) trial has found that early aggressive statin therapy patients with acute coronary syndrome (ACS) significantly reduces the plaque volume (PV) non-culprit lesions. purpose present study was to evaluate clinical factors have an impact on regression using therapy.Serial intravascular ultrasound observations over 8-12 months were performed 252 ACS receiving pitavastatin or atorvastatin. Linear analysis...
Production of granite in the middle to lower crust and emplacement into upper at convergent plate margins is dominant mechanism crustal differentiation. The Fosdick Mountains West Antarctica host migmatitic paragneisses orthogneisses corresponding granites emplaced as dikes, sills small plutons, which record processes intracrustal differentiation along East Gondwana margin. U–Pb chronology on magmatic zircon from reveals c. 358–336 Ma 115–98 Ma, consistent with a polyphase tectonic evolution...
Transplantation of mesenchymal stromal cells (MSCs) is an emerging therapy for the treatment heart failure. However, delivery method MSC currently suboptimal. The use self-assembling peptide hydrogels, including PuraMatrix
Background The prognostic value of non-obstructive, CT low-dense plaques (CTLDP) on multislice computed tomography (MSCT) for the prediction nonfatal acute myocardial infarction (AMI), unstable angina (UA) and cardiac death has not yet been defined. Methods Results In present study 810 patients who underwent MSCT had non-obstructive coronary artery disease were followed up occurrence AMI, UA death. Non-obstructive CTLDP defined as with a density <68 Hounsfield units, accompanied by mild to...
Background: Few studies have serially monitored the change of coronary plaque after statin therapy using multiple imaging modalities. Methods and Results: A prospective open-label trial was performed to assess regression stabilization following 52 weeks pitavastatin treatment (2 mg/day). Coronary segments that included most diseased 90 patients determined on angioscopy were analyzed intravascular ultrasound (IVUS). The yellow grade each 46 who had matched IVUS data evaluated angioscopy....
The ∼50 Myr old Izu–Bonin–Mariana (IBM) arc consists mostly of Oligocene middle and lower crust that underlies the upper crust; these units are in turn covered by Quaternary volcanic rocks. Seismic imaging, forearc geology, Ocean Drilling Program drilling magnetic anomalies suggest most IBM was created Eocene–Oligocene times. However, remnants this have never been found at northern end arc, where it is colliding with Honshu (Izu collision zone). Two batholiths zone (the Tanzawa tonalites...
Amine emissions from post-combustion CO2 capture systems can pose significant environmental risks and cause high operational costs. Conventional packed bed washing methods often fail to effectively mitigate mist-driven amine emissions, which constitute a major portion of total in such systems. To address this challenge, Toshiba Energy Systems & Solutions Corporation has developed novel spray-washing system tested using bench-scale test plant. The demonstrated superior efficiency removing...
Background — A lifetime mechanical solution for advanced heart failure must be reliable, with a low risk of life-threatening complications. After extensive laboratory testing, we began clinical trials an axial flow pump long-term treatment New York Heart Association class IV, transplant-ineligible patients. Methods and Results The Jarvik 2000 is continuous device that implanted in the apex left ventricle offloading to descending thoracic aorta. Skull-based percutaneous power delivery was...
Apolipoprotein (apo) J, clusterin, is ubiquitously expressed in many tissues, and a component of high-density lipoproteins (HDLs). There experimental evidence that it may be anti-atherogenic through its effects on cholesterol transport, smooth muscle cell proliferation lipid peroxidation. HDLs containing apo J A-I carry paraoxonase (PON1), which protects low-density from oxidative modification; however, the extent to affects coronary heart disease (CHD) not known. We have developed sandwich...
Background: The noninvasive methods for predicting a successful pulmonary vein isolation (PVI) have not been well described. aim of this study was to assess the usefulness P‐wave signal‐averaged electrocardiogram (P‐SAECG) in chance PVI patients with atrial fibrillation (AF). Methods: A P‐SAECG recorded before (pre), 1 day after, and 3–4 months after 51 AF (41, paroxysmal AF; 10, persistent AF). Three‐dimensional electroanatomic mapping (3D‐EAM) right left atria PVs performed 10 analyze...