A5101668332- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Escherichia coli research studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Antibiotic Resistance in Bacteria
- Neuroinflammation and Neurodegeneration Mechanisms
- Cardiac Ischemia and Reperfusion
- Clostridium difficile and Clostridium perfringens research
- Mycobacterium research and diagnosis
- Organ Transplantation Techniques and Outcomes
- Sepsis Diagnosis and Treatment
- Bacteriophages and microbial interactions
- Urologic and reproductive health conditions
- Hormonal and reproductive studies
- Anesthesia and Pain Management
- Estrogen and related hormone effects
- Genetics and Physical Performance
- Sperm and Testicular Function
- Neuroscience and Neuropharmacology Research
- Urological Disorders and Treatments
- Protease and Inhibitor Mechanisms
- RNA regulation and disease
- Airway Management and Intubation Techniques
- Ureteral procedures and complications
- Salmonella and Campylobacter epidemiology
The First Affiliated Hospital, Sun Yat-sen University
2016-2025
Sun Yat-sen University
2016-2025
Nanjing Agricultural University
2020-2023
Nantong University
2021-2023
Xi'an Jiaotong University
2020-2023
Chinese Academy of Agricultural Sciences
2020
Harbin Veterinary Research Institute
2020
State Council of the People's Republic of China
2019
Jilin Agricultural University
2019
University of Virginia
2014-2017
A Janus evaporator with a low-tortuosity pore structure is reported for water generation from highly salty water. The unique together the asymmetric wettability enables to float on excellent salt excretion properties and heat localization, resulting in stable steam generation.
ExPEC is an important pathogen that causes diverse infection in the human extraintestinal sites. Although avian-source phylogroup F Escherichia coli isolates hold a high level of virulence traits, few studies have systematically assessed pathogenicity and zoonotic potential E. within F. A total 1,332 strains were recovered from chicken colibacillosis China 2012 to 2017. About 21.7% chicken-source presented We characterized both genotypically phenotypically. There was widespread prevalence...
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrotic lung disease with high mortality morbidity. ASPN (asporin), member of the small leucine-rich proteoglycan family, plays crucial roles in tissue injury regeneration. However, precise pathophysiological role its molecular mechanisms IPF remain unknown. We sought to investigate during development therapeutic potential targeting ASPN-related signaling pathways. In our study, three microarray datasets were downloaded from...
Avian pathogenic Escherichia coli (APEC) is recognized as a primary source of foodborne extraintestinal E. (ExPEC), which poses significant risk infections in humans. The potential human infection with ST117 lineage APEC/ExPEC from poultry particularly concerning. However, relatively few whole-genome studies have focused on an emerging ExPEC lineage. In this study, the complete genomes 11 avian isolates and draft 20 China were sequenced to reveal genomic islands large plasmid composition...
The extended-spectrum cephalosporin resistant E. coli from food animals transferring to community settings of humans causes a serious threat public health. Unlike phylogroup B2 strains, the clinical significance isolates in F is not well revealed. Here, we report on collection (n = 563) recovered chicken colibacillosis tissues and retail raw meat samples Eastern China. There was an overlapped distribution MLST types between colibacillosis-origin meat-source coli, including dominant STs...
Volatile anesthetics have been widely applied during surgery, but the potential mechanisms by which they influence loss of consciousness (LOC), anesthesia maintenance, and recovery (ROC) from remain largely unknown. Recent studies suggested that anesthesia-induced unconsciousness may be due to specific interactions between neural circuits regulate sleep wakefulness. Supramammillary (SuM) glutamatergic neurons are essential for sleep-wakefulness regulation. However, whether SuM involved in...
<title>Abstract</title> Plasma membrane integrity is vital not only for cell survival but also nearly all aspects of functioning. Mechanical stress can cause plasma damage, it known whether there are large molecules (proteins) that control integrity. Here we constructed a 384-well cellular stretch system delivers precise, reproducible mechanical strain to adherent cells. Using the system, screened 10,843 siRNAs targeting 2,726 multi-pass transmembrane proteins stretch-induced permeability...
Background: Neuropathic pain is one of the common complications after spinal cord injury (SCI), affecting individuals’ quality life. The molecular mechanism for neuropathic SCI still unclear. We aimed to discover potential genes and microRNAs (miRNAs) related by bioinformatics method. Methods: Microarray data GSE69901 were obtained from Gene Expression Omnibus (GEO) database. Peripheral blood samples individuals with or without collected. Twelve 13 as controls included in downloaded...
As a cutting-edge two-dimensional (2D) material, black phosphorous (BP) has been demonstrating promising performance in the field of near-field radiative heat transfer (NFRHT) due to excitation ability its surface plasmon polaritons. Here, we have systematically demonstrated effect mechanical strain on NFRHT between two separate BP sheets. First-principles calculations predict that certain amount (4% along biaxial or 6% zigzag (ZZ)) can trigger an orthogonal switch anisotropic optical...
Perioperative discontinuation of aspirin is often considered due to bleeding concern. We determined whether this affected neurological outcome after brain ischemia. Adult male Sprague–Dawley rats were subjected a 90-minute right middle cerebral arterial occlusion (MCAO). They received 30 mg/kg/day via gastric gavage: 1) for 2 days at 5 before MCAO; 2) MCAO and 3 3) 7 or 4) MCAO. Neurological was evaluated the Ischemic penumbral cortex harvested 1 determining Notch intracellular domain...
Abstract Higher incidence and worse outcomes of laryngospasm during general anesthesia in children than adults have been reported for many years, but few prevention measures are put forward. Efficacy lidocaine has argued years we decided to design this network meta-analysis assess the efficacy lidocaine. We conducted an electronic search six sources finally included 12 Randomized Controlled Trials including 1416 patients. A direct comparison between placebo revealed had effect on preventing...
Abstract Background Microglia are highly motile phagocytic cells in the healthy brain with surveillance and clearance functions. Although microglia have been shown to engulf cellular debris following insult, less is known about their function absence of injury. Propofol can inhibit microglial activity, including phagocytosis. Milk fat globule epidermal growth factor 8 (MFG-E8), as a regulator microglia, plays an essential role process. However, whether MFG-E8 affects alteration phagocytosis...
Objective Stroke is a severe complication of atrial fibrillation (AF). We aimed to discover key genes and microRNAs related stroke risk in patients with AF using bioinformatics analysis. Methods GSE66724 microarray data, including peripheral blood samples from eight without stroke, were downloaded the Gene Expression Omnibus (GEO) database. Differentially expressed (DEGs) between identified GEO2R online tool. Functional enrichment analysis was performed DAVID A protein–protein interaction...
// Wei Sun 1, * , Zeting Qiu 2, Wulin Tan Zhongqi Liu 1 Zhongxing Wang 2 Wenqi Huang # and Minghui Cao Department of Anesthesiology, Yat-sen Memorial Hospital, University, Guangzhou, Guangdong, China The First Affiliated Hospital These authors contributed equally to this work took on the correspondence responsibility Correspondence to: Cao, email: caominghui_sysu@163.com Huang, huangwenqi86@aliyun.com Keywords: oral tongue squamous cell carcinoma, marital status, SEER, survival analysis,...
Abstract Background Astrocyte Connexin 43 (Cx43) is essential for the trophic and protective support of neurons during brain ischemia reperfusion (I/R) injury. It believed that dexmedetomidine participates in Cx43-mediated effects. However, its mechanisms remained unclear. This study aims to address relationship regulation among them. Methods Adult male Sprague-Dawley rats were allocated 90-min right middle cerebral arterial occlusion with or without pretreatment (5 μg/kg). Neurological...
Purpose: Intravenous patient-controlled analgesia (IV-PCA) has been widely used; however, regimen criteria have not yet established. In China, the most often used opioid is sufentanil, for which repeated doses are a concern, and empirical flurbiprofen axetil (FBP) as an adjuvant. We hypothesized that hydromorphone would be better choice also evaluated effectiveness of FBP Methods: This historical cohort study was conducted in two tertiary hospitals China included 12,674 patients using or...
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrotic lung disease with poor prognosis few treatment options. Dapper homolog 2 (DACT2), member of the DACT gene family, plays crucial roles in tissue development injury. However, its functions molecular mechanisms IPF remain largely unknown. We aimed to investigate role DACT2 therapeutic potential targeting related signaling pathways.In our study, adeno-associated virus serotype 6 (AAV6)-mediated overexpression was assessed...
Avian pathogenic Escherichia coli (APEC) is a notable subpathotype of the nonhuman extraintestinal E. (ExPEC). Recognized as an foodborne pathogen, zoonotic potential APEC/ExPEC allows for cross-host transmission via APEC-contaminated poultry meat and eggs. ProQ, RNA binding protein, evolutionarily conserved in coli. However, its regulatory roles biofilm formation virulence have not been explored. In this study, proQ deletion APEC strain FY26 significantly compromised biofilm-forming...
Abstract A one-pot synthesis of functionalized benzofurans has been developed via O-alkylation, carbon–carbon coupling/cyclization, and dehydration/olefination tandem reactions from phenacyl bromide phenols under microwave irradiation solvent-free conditions in the presence mineral-supported reagent inorganic base. The best selectivity for forming benzofuran product achieved with Na2CO3 as a order activity base is follows: K2CO3 > NaHCO3 KHCO3 Na2SO3 KOH K3PO4 NaOH KH2PO4 KOAc. This novel...
Background: Recent observational studies have reported a negative association between physical activity and chronic back pain (CBP), but the causality of remains unknown. We introduce bidirectional Mendelian randomization (MR) to assess potential causal inference CBP. Materials Methods: This two-sample MR used independent genetic variants associated with CBP as instruments from large genome-wide (GWASs). The effects both directions (physical activity) were examined. Inverse variance-weighted...
The aim of the present study was to predict key genes and proteins associated with complex regional pain syndrome (CRPS) using bioinformatics analysis. gene expression profiling microarray data, GSE47603, which included peripheral blood samples from 4 patients CRPS 5 healthy controls, obtained Gene Expression Omnibus (GEO) database. differentially expressed (DEGs) in compared controls were identified GEO2R online tool. Functional enrichment analysis then performed Database for Annotation...