A5101781995- Healthcare and Venom Research
- Ocular Surface and Contact Lens
- Traditional Chinese Medicine Studies
- Glaucoma and retinal disorders
- Pharmacological Effects of Natural Compounds
- Food Quality and Safety Studies
- Corneal Surgery and Treatments
- Medical Research and Treatments
- Cell Adhesion Molecules Research
- Ocular Oncology and Treatments
- Spine and Intervertebral Disc Pathology
- Advancements in Battery Materials
- Ocular Disorders and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Atherosclerosis and Cardiovascular Diseases
- Advanced Battery Technologies Research
- Systemic Lupus Erythematosus Research
- Autophagy in Disease and Therapy
- Medical Imaging and Analysis
- Myofascial pain diagnosis and treatment
- Intraocular Surgery and Lenses
- Plant-based Medicinal Research
- Ophthalmology and Visual Impairment Studies
- Curcumin's Biomedical Applications
- Tendon Structure and Treatment
Hebei University of Technology
2025
Wuxi No.2 People's Hospital
2011-2024
Jiangnan University
2024
Nantong University
2021-2024
Taizhou People's Hospital
2024
Nanjing Medical University
2010-2024
Shandong University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Tarim University
2024
Qilu Hospital of Shandong University
2024
Inducing autophagy and inhibiting apoptosis may provide a therapeutic treatment for atherosclerosis (AS). For the of progressive AS, arsenic trioxide (ATO) has been used to coat vascular stents. However, effect ATO on macrophages is still unknown. Therefore, aims this study were characterize effects mechanism actions in macrophages. Our results showed that ATO-induced activation was an earlier event than inhibition expression markers foam cells. Nuclear transcription factor EB (TFEB)...
Rationale: Atherosclerosis plaque rupture (PR) is the pathological basis and chief culprit of most acute cardiovascular events death. Given complex important role macrophage apoptosis autophagy in affecting stability, an unanswered question include whether, how, immunity-related GTPase family M protein (IRGM) its mouse orthologue IRGM1 affect survival atherosclerotic stability. Methods: To investigate whether serum IRGM ST-segment elevation myocardial infarction (STEMI) patients related to...
Background and Aims: Reliable novel noninvasive biomarkers for the diagnosis of advanced liver fibrosis are urgently needed in clinical practice. We aimed to investigate accuracy plasma Follistatin-like protein 1 (FSTL-1) chronic diseases. Approach Results: collected cross-sectional data a derivation cohort (n = 86) validation 431), totaling 517 subjects with biopsy. Advanced was defined by METAVIR pathological score (F ≥3). Dual cutoff values were explored. In cohort, FSTL-1 levels...
Abstract The long noncoding RNA antisense in the INK4 locus (ANRIL) plays a critical role development of atherosclerosis. However, precise effect ANRIL on endothelial dysfunction remains unclear. In this study, we investigated expression patients with coronary artery disease and elucidated molecular mechanism underlying its effect. was detected blood plasma 111 patients. We analysed correlation between markers. also examined regulation dysfunction. levels were increased acute syndrome. is...
Sodium-ion batteries (SIBs) are emerging as promising alternatives to lithium-ion (LIBs) because of their low cost and abundant resources. However, safety reliability under mechanical abusive loading remain...
<h3>Aim</h3> To characterise the pharmacokinetics of triamcinolone acetonide (TA) in various ocular tissues following a single sub-Tenon injection. <h3>Methods</h3> Twenty-one Chinchilla adult pigmented rabbits received injection TA (40 mg 0.4 ml) their right eyes. Three animals were killed at each designated time points (3 h, 1 day, 3 days, 7 14 21 days and 30 days) globes snap frozen dissected into aqueous, iris-ciliary body, vitreous, neuroretina retinal pigment epithelium (RPE)/choroid....
To investigate the change and recovery of choroid thickness after short-term application 1% atropine gel its influencing factors in 6-7-year-old children.71 right eyes 71 children were enrolled divided into myopia control group. was administered twice a day for one week then stopped. Spherical equivalent (SE), accommodative amplitude (AA), keratometry (K), axial length (AL), choroidal (CT) obtained at baseline 1st, 4th, 8th weeks. CT measured subfovea 1 mm, 2 3 mm temporal, superior, nasal,...
At present, relevant studies have found that baicalin can improve macular edema (ME) caused by glaucoma, but the effect on branch retinal vein occlusion (BRVO) is still unclear. The CoCl2-stimulated ARPE-19 cells were treated with different concentrations of and detected cell viability, apoptosis oxidative stress. Next, hypoxia-inducible factor-1α (HIF-1α) overexpression vector or siRNA transfected into cells, changes detected. We searched potential binding proteins HIF-1α through online...
To investigate the effects of pterygium on corneal cell and nerve density in patients with unilateral using vivo laser scanning confocal microscopy (LSCM).In this cross-sectional study, 24 who were treated Department Ophthalmology Second People's Hospital Wuxi City from April 2018 to July analyzed. Each eye its fellow imaged by LSCM. The basal epithelial cells, anterior stromal posterior dendritic endothelial cells adjacent clear cornea was measured. In eyes, central cornea, nasal...
Neutrophil extracellular traps (NETs) closely link inflammation and thrombosis. The immune-related GTPase family M protein (IRGM) its ortholog of mouse IRGM1 are positively correlated with plaque rupture during atherosclerosis process. However, whether how IRGM/IRGM1 affects NETs formation atherosclerotic thrombosis remains unknown, which will further promote the development antithrombotic treatment tools.The thrombi images, platelet activation makers were detected in serum STEMI patients...