A5023592772- Head and Neck Cancer Studies
- Electromagnetic wave absorption materials
- Angiogenesis and VEGF in Cancer
- Advanced Antenna and Metasurface Technologies
- Radiomics and Machine Learning in Medical Imaging
- Cancer-related molecular mechanisms research
- Retinal Diseases and Treatments
- Esophageal Cancer Research and Treatment
- Head and Neck Surgical Oncology
- MRI in cancer diagnosis
- Advanced Radiotherapy Techniques
- Cholangiocarcinoma and Gallbladder Cancer Studies
- MicroRNA in disease regulation
- Flame retardant materials and properties
- RNA modifications and cancer
- Conducting polymers and applications
- Lung Cancer Research Studies
- Glaucoma and retinal disorders
- Metal Extraction and Bioleaching
- Salivary Gland Tumors Diagnosis and Treatment
- Extraction and Separation Processes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Transition Metal Oxide Nanomaterials
- Cell Adhesion Molecules Research
- Modular Robots and Swarm Intelligence
China State Shipbuilding (China)
2020-2024
Central South University
2020-2024
Zhejiang Cancer Hospital
2015-2024
YangPu Geriatric Hospital
2024
Xiangya Hospital Central South University
2021-2024
Zunyi Medical University
2024
Huazhong University of Science and Technology
2023-2024
Chinese Academy of Sciences
2019-2022
Cancer Hospital of Chinese Academy of Medical Sciences
2019-2022
Sun Yat-sen University
2016-2021
To identify subgroups of patients with early-stage (pT1-2N0M0) oral tongue squamous cell carcinoma (OTSCC) who may benefit from postoperative radiotherapy (PORT).
The incidence of nasopharyngeal carcinoma (NPC) is rare, but a certain amount mortality remains in NPC patients. Our study aimed to identify candidate genes as biomarkers for screening, diagnosis, and therapy.We investigated two microarray profile datasets GSE64634 GSE12452 screen the potential differentially expressed (DEGs) NPC. Gene ontology Kyoto Encyclopedia Genes Genomes (KEGG) pathway enrichment analysis DEGs were also performed. A protein-protein interaction (PPI) network was...
Significance Despite being discovered a long time ago, the functional properties of VEGF-B remain poorly understood. However, several clinical treatments use drugs that target and other VEGF family members. It is therefore crucial to gain deeper insights into function underlying mechanisms. Here, we found has potent antioxidative functions, making it member show such property. We further identified critical downstream effector VEGF-B, Gpx1, through which protects against retinal...
Significance Caveolin-1 (Cav-1) is a major structural protein of caveolae found in cell membranes and critical for numerous cellular functions. However, it remains unclear whether Cav-1 plays role ocular neovascularization, cause blindness. In this study, we that the gene deletion exacerbates cavtratin, permeable peptide mimicking function, inhibits neovascularization by targeting multiple components angiogenesis. Importantly, combined administration cavtratin anti–VEGF-A more effectively,...
Breast cancer (BRCA) is the most common tumor in women, and lipid metabolism involvement has been demonstrated its tumorigenesis development. However, role of metabolism-associated genes (LMAGs) immune microenvironment prognosis BRCA remains unclear.A total 1076 patients with were extracted from The Cancer Genome Atlas database randomly assigned to training cohort (n = 760) or validation 316). Kaplan-Meier analysis was used assess differences survival. Consensus clustering performed...
This paper proposes a genetic algorithm (GA)-enabled co-design method for the development of metamaterials with on-demand microwave reflectivity and infrared (IR) emissivity. First, we proposed multilayered metamaterial based on metasurface hexagonal patch ring patterns. An equivalent circuit model (ECM) was then established to metamaterial. To achieve broadband low reflectivity, GA this ECM adopted optimize structural parameters A task accomplished by setting judgment condition in IR With...
Conductive porous carbon nanoparticles (PCNs) with narrow pore-size distribution are considered as a versatile platform for material design and multiapplications, but their fabrication still remains challenge so far. In this work, series of conductive PCNs were prepared from conjugate microporous polymer (CMP) precursors via controlled calcination strategy. It is found that the chemical structures CMP have great influence on micro–nano morphology, pore distribution, electrical conductivity...
Abstract Vascular endothelial growth factor B (VEGF-B) was discovered a long time ago. However, its role in hyperglycemia- and VEGF-A inhibition-induced retinal apoptosis remains unknown thus far. Yet, drugs that can block VEGF-B are being used to treat patients with diabetic retinopathy other ocular neovascular diseases. It is therefore urgent have better understanding of the function these pathologies. Here, we report both streptozotocin (STZ)-induced diabetes rats Macugen intravitreal...
We assessed the efficacy and safety of nimotuzumab plus neoadjuvant chemotherapy followed by concurrent chemoradiotherapy for Chinese patients with locoregionally advanced nasopharyngeal carcinoma. Clinical data from 210 nonmetastatic carcinoma diagnosed between May 2008 April 2014 were retrospectively reviewed. All initially treated chemoradiotherapy. Ninety-five received cisplatin-based adjuvant chemotherapy. The median follow-up duration was 48 months. Locoregional relapse distant...
Cisplatin (CDDP) is a commonly used drug for gallbladder cancer (GBC) chemotherapy. However, resistance to CDDP treatment results in relapse. Therefore, there need the development of more effective strategies overcome chemoresistance. Dual‑specificity phosphatase 1 (DUSP1) was reported be involved number chemotherapeutic agents and revealed highly expressed CDDP‑resistant GBC cells CDDP‑treated tumor types compared with normal or tissues present study. DUSP1 inhibit cytotoxicity two cell...
Abstract Background We evaluated the treatment response and predictive factors for overall survival (OS) in patients with hepatocellular carcinoma (HCC) portal vein tumour thrombosis (PVTT), who underwent stereotactic body radiotherapy (SBRT). Additionally, we developed validated a personalised prediction model patient survival. Methods Clinical information was retrospectively collected 80 HCC PVTT, were treated SBRT at Cancer Hospital of University Chinese Academy Sciences (Zhejiang...