- Genital Health and Disease
- Urological Disorders and Treatments
- Urologic and reproductive health conditions
- Sexual function and dysfunction studies
- Prostate Cancer Diagnosis and Treatment
- Mitochondrial Function and Pathology
- Hormonal and reproductive studies
- Medical Malpractice and Liability Issues
- Vascular anomalies and interventions
- Chromatin Remodeling and Cancer
- Virus-based gene therapy research
- Histiocytic Disorders and Treatments
- Cancer Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Genetic and Kidney Cyst Diseases
- Urinary Bladder and Prostate Research
- Sarcoma Diagnosis and Treatment
- Reproductive Biology and Fertility
- Infectious Disease Case Reports and Treatments
- Sperm and Testicular Function
- Prostate Cancer Treatment and Research
- Hair Growth and Disorders
- Tumors and Oncological Cases
- RNA regulation and disease
- Female Genital Mutilation/Cutting Issues
Jiangsu Province Hospital
2013-2024
Nanjing Medical University
2013-2024
Shanghai Skin Disease Hospital
2014
Delayed first medical consultation (patient's delay) is quite common in cases of penile carcinoma (PC), but its reasons and impacts remain unclear. We conducted this study to ascertain risk factors resulting delayed treatment seeking evaluate influence on prognosis.From 2004 2010 at 4 centers, 254 patients were enrolled into from 262 consecutive PC cases. Patients' sexual performance was investigated using the International Index Erectile Function (IIEF)-15 sixth-month end after treatment....
No AccessJournal of UrologyAdult Urology1 Nov 2014Glans Preservation Contributes to Postoperative Restoration Male Sexual Function: A Multicenter Clinical Study Glans Preserving Surgery Jie Yang, Jing Chen, Xin-feng Wu, Ning-jing Song, Xiao-yun Xu, Quan Li, Di Qiao, Jia-yi Zhang, Wei Wang, Huang Su, Zeng-jun Jian-tang and Ning-hong Song YangJie Yang Department Urology, First Affiliated Hospital Nanjing Medical University, Nanjing, People's Republic China , ChenJing Chen General Surgery,...
Background: TP53-regulated inhibitor of apoptosis 1 (TRIAP1), also known as p53 cell survival factor or p53CSV, is reported to be associated with resistance in different human malignancies, but the potential role TRIAP1 penile carcinoma (PeCa) has not been well studied. This study aimed analyze association between expression and clinical outcome PeCa patients. Methods: Bioinformatics was used differential compared normal tissues Gene Expression Omnibus (GEO) Dataset (GSE57955). The tumor...
Interdigitating dendritic cell sarcoma (IDCS) and retroperitoneal leiomyosarcoma are rare tumors. The optimal diagnosis, treatment prognosis remain unknown. current case report presents a 46-year-old male who exhibited with left renal mass combined periprostatic mass. patient underwent surgery twice, respectively for the resection of two masses. postoperative pathological examination confirmed diagnosis IDCS presenting in kidney pelvis. To best our knowledge, it is first appearance same patient.
We developed two nomograms to predict the presence of inguinal lymph node metastasis (ILNM) and or more histologically positive nodes (ILNs) one ILN with extranodal extension (ENE) in penile cancer patients clinically (ILNs).This study enrolled 75 squamous cell carcinoma (PSCC) ILNs. A binary logistic regression model was taken screen out risk factors for ILNM ILNs ENE side. Nomograms were plotted based on results multivariate analysis.Our analysis demonstrated that pathological grade,...
To study the molecular mechanism of epididymal protease inhibitor (Eppin) modulating process prostate specific antigen (PSA) digesting semenogelin (Sg).
We described a modified surgical procedure for repairing concealed penis and compared the efficacy feasibility of repair with traditional repair.From March 2003 to December 2012, 96 patients were recruited undergo penile at our centre. Modified performed respectively on 46 50 cases. operative time, intraoperative blood loss, cosmetic result scars, postoperative retraction, complications.All operations completed successfully without serious complications. The mean scar between two methods...
We conducted this study to investigate whether glans-reconstruction with preputial flap would be more helpful for post-operative restoration of patients' sexual potency than primary closure. From 2007 2013 at four centres, 46 cases reconstructed and 59 closure were selected the investigation from 142 consecutive superficial glans cancer, largest diameter lesion ≤2.5 cm, who undergoing glans-preserving surgery (GPS). Subjective evaluation performance was investigated using International Index...
ABSTRACT: In this study, we investigated the safety and feasibility of glans‐preserving surgery for superficial penile squamous cell carcinoma. Young patients with primary tumors exhibiting favorable histologic features were best suited organ‐sparing procedures, enabling them to avoid sexual disturbances. The study included 12 patients, 38–53 years age (median 46 years), lesions involving glans penis, coronary sulcus, or shaft skin. After clinical staging grading, those offered a procedure...
To assess the safety and efficacy of laparoscopic retroperitoneal resection for lymphatic cysts. A retrospective analysis was conducted based on clinical data from eight patients with hydronephrosis caused by All underwent cyst received postoperative follow-up. follow-up ultrasound performed postoperatively every 6–12 months to evaluate recovery hydronephrosis. operations were successful, their pathological results revealed walls. The operation time ranged 43 88 min (mean: 62 min), a blood...
Penile cancer (PC) is a rare malignant tumor, whose distant metastasis (DM) associated with the poorest outcomes. The risk factors DM and prognosis of PC remain elusive. This study was aimed at investigating constructing prediction models DM.
Experimental autoimmune prostatitis (EAP)-induced persistent inflammatory immune response can significantly upregulate the expression of N-methyl-D-aspartic acid (NMDA) receptors in paraventricular nucleus (PVN). However, mechanism has not yet been elucidated. Herein, we screened out target prostate-derived inflammation cytokines (PDICs) by comparing cytokine levels peripheral blood and cerebrospinal fluid (CSF) between EAP rats their controls. After identifying PDIC, qualified males initial...
Background Voltage-dependent anion channel (VDAC), a protein, exists in the outer mitochondrial membrane of somatic cells and is involved multiple physiological pathophysiological processes. Up until now, little has been known about VDAC male germ cells. In present study, relationship between human sperm motility was explored.
Objective: Voltage-dependent anion channel (VDAC), a protein, exists in the outer mitochondrial membrane of somatic cells and is involved multiple physiological pathophysiological processes. Up until now, little has been known about VDAC male germ cells. In present study, relationship between human sperm motility was explored.