Hongli Sun

ORCID: 0009-0003-1898-1329
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About
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Research Areas
  • Stress Responses and Cortisol
  • Tryptophan and brain disorders
  • Anesthesia and Neurotoxicity Research
  • Pneumonia and Respiratory Infections
  • Neuroendocrine regulation and behavior
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Birth, Development, and Health
  • Neuroscience and Neuropharmacology Research
  • Respiratory viral infections research
  • Bacterial Infections and Vaccines
  • Genetics and Neurodevelopmental Disorders
  • Antimicrobial Resistance in Staphylococcus
  • Bacterial Identification and Susceptibility Testing
  • Bone and Joint Diseases
  • Family Support in Illness
  • Respiratory and Cough-Related Research
  • Rheumatoid Arthritis Research and Therapies
  • Metabolism, Diabetes, and Cancer
  • PI3K/AKT/mTOR signaling in cancer
  • Growth Hormone and Insulin-like Growth Factors
  • Diet and metabolism studies
  • Medicinal Plant Pharmacodynamics Research
  • Consumer Behavior in Brand Consumption and Identification
  • Spondyloarthritis Studies and Treatments
  • Posttraumatic Stress Disorder Research

Xi'an Jiaotong University
2014-2025

Xi’an Children’s Hospital
2015-2025

Peking Union Medical College Hospital
2009-2025

Chinese Academy of Medical Sciences & Peking Union Medical College
2009-2025

Wuxi People's Hospital
2011-2024

Nanjing Medical University
2011-2024

Beijing University of Technology
2023

Anhui Medical University
2018

First Affiliated Hospital of Anhui Medical University
2018

First Affiliated Hospital of Xi'an Jiaotong University
2016-2017

Metformin recently gained traction as potential anti-endometrial cancer agent for its new applications. However, the underlying mechanisms of anti-cancer effect metformin in endometrial have not yet been fully elucidated. Sixty-five patients diagnosed carcinoma were grouped into (n = 33) and non-treatment mixed 32) analysis. Thirty healthy donors recruited controls. We attempt to investigate on Ki-67, PI3K, p-AKT, p-S6K1, p-4EBP1 staining human by immunohistochemical staining. found that...

10.1080/09513590.2017.1409714 article EN Gynecological Endocrinology 2017-11-28

Streptococcus pneumoniae, the leading pathogen of bacterial infections in infants and elderly, is responsible for pneumococcal diseases with severe morbidity mortality. Emergence drug-resistant strains presented new challenges treatment prevention. Vaccination has proven to be an effective means preventing infection worldwide. Detailed epidemiological information antibiotic susceptibilities serotype distribution will great help management infections. A total 881 S. pneumoniae isolates were...

10.1186/s12879-017-2880-0 article EN cc-by BMC Infectious Diseases 2017-12-01

Images, with their direct content experience, have become essential in tourists’ narratives of accommodation sharing. Although visual plays an important role influencing user decisions, research on hotel images often neglects the significance sensory elements. Sensory elements help shape perceptions and evaluations experiences. This study explores how marketing review affect sales from a perspective. The employs combination hybrid machine vision econometric methods to examine visual,...

10.1177/00472875241310818 article EN Journal of Travel Research 2025-01-28

Pneumocystis jirovecii pneumonia (PJP) is a common opportunistic infection. With the wide application of glucocorticosteroids and immunosuppressants, incidence mortality rates PJP in connective tissue disease (CTD) patients with interstitial lung (ILD) are increasing. We retrospectively enrolled consecutive CTD-ILD our center between January 2014 December 2022. Cox regression models were constructed to explore prognostic factors CTD-ILD-PJP patients. There 159 [60 (51, 68) years, 61.0%...

10.1007/s10067-025-07392-1 article EN cc-by Clinical Rheumatology 2025-03-06

Background The relationship between the triglyceride-glucose (TyG) index, its combination with obesity indicators, and depression remains understudied in American population. Methods This cross-sectional study analyzed data from 10,423 adults National Health Nutrition Examination Survey (NHANES) conducted 2005 2020. We employed multivariable logistic regression analysis, smoothing techniques, generalized additive models, stratified analyses, sensitivity analyses to examine TyG, (TyG-WC,...

10.3389/fpsyt.2025.1533819 article EN cc-by Frontiers in Psychiatry 2025-03-10

Adolescence is a time of continued brain maturation, particularly in limbic and cortical regions, which undoubtedly plays role the physiological emotional changes. Juvenile rats repeatedly exposed to prenatal stress (PS) exhibit behavioral features often observed neuropsychiatric disorders including depression. However, date underlying neurological mechanisms are still unclear. In current study, juvenile offspring whose mothers were PS evaluated for depression-related behaviors open field...

10.1371/journal.pone.0081775 article EN cc-by PLoS ONE 2013-11-20

Nocturnal enuresis (NE) has a negative impact on children's health and imposes long-term burden families. With economic development cultural improvements, parents medical professionals pay more attention to NE. The aim of this study was investigate the prevalence risk factors NE among children ages 5-12 years in Xi'an, China.A stratified cluster sampling method used conduct cross-sectional 10 kindergartens 20 primary schools Xi'an. We univariate analysis compare prevalences characteristics...

10.1186/s12887-020-02202-w article EN cc-by BMC Pediatrics 2020-06-22

Abstract Objective Thise study is aimed to identify the biomarkers for predicting refractory Mycoplasma pneumoniae pneumonia in Chinese children at time of hospital admission. Methods The case control retrospectively analyzed clinical characteristics and laboratory results pediatric patients presenting with common (CMPP RMPP). Overall, there were 216 cases CMPP group 88 RMPP group. Venous blood was collected, serum ferritin (SF), lactate dehydrogenase (LDH), D-dimer, C-reactive protein...

10.1186/s12931-020-01577-9 article EN cc-by Respiratory Research 2021-03-22

To investigate the occurrence of vancomycin-resistant enterococci (VRE) isolated from patients in Peking Union Medical College Hospital, Beijing, China 2011 to 2017, and evaluate their resistance mechanisms genetic relatedness.All isolates were identified using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF). Antibiotic susceptibility testing was performed broth microdilution method. Molecular characterization detected by PCR sequencing. Genotyping VRE multilocus...

10.1016/j.jmii.2018.12.008 article EN cc-by-nc-nd Journal of Microbiology Immunology and Infection 2019-02-11

Background Metformin is a well-tolerated biguanide drug used for decades to treat type 2 diabetes mellitus. In recent years, long-term administration of metformin has been found reduce carcinogenic risk cancers derived from various tissues. However, its cellular and molecular mechanisms anticancer action in the endometrial cancer (EC) have not yet fully elucidated. Patients Methods Sixty patients diagnosed as carcinoma were grouped into (n = 30) non-treatment mixed analysis. Thirty healthy...

10.1097/igc.0000000000000818 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2016-09-21

The purpose of this study was to explore whether earthquake-related maternal Post-Traumatic Stress Disorder (PTSD) is associated with impaired development infants. Participants included 86 women who were pregnant during or after the earthquake in Ningqiang county, and their children. Data collected from February March 2012. PTSD questionnaire (PTSD Checklist, Civilian Version (PCL-C)) used measure effect on mothers, that scores greater than 50 indicate presence PTSD. Each child assessed...

10.1371/journal.pone.0168747 article EN cc-by PLoS ONE 2017-04-03

To evaluate the performance of a multiplex real-time polymerase chain reaction (PCR) assay for simultaneous identification Aspergillus, Cryptococcus neoformans, and Pneumocystis jirovecii from sputum.Sputum samples (n=537) patients with suspected invasive fungal infection (IFI) were collected four centers; they tested by both PCR DNA sequencing. sequencing was considered as reference method, evaluated determining sensitivity, specificity, positive predictive value (PPV), negative (NPV). The...

10.2147/idr.s379043 article EN cc-by-nc Infection and Drug Resistance 2022-10-01
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