Xiyao Chen

ORCID: 0009-0003-7315-2427
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About
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Research Areas
  • Photonic and Optical Devices
  • Photonic Crystals and Applications
  • Optical Coatings and Gratings
  • Semiconductor Lasers and Optical Devices
  • Advanced Fiber Optic Sensors
  • Plasmonic and Surface Plasmon Research
  • Air Quality and Health Impacts
  • Fern and Epiphyte Biology
  • Sport and Mega-Event Impacts
  • Advanced Fiber Laser Technologies
  • Heavy metals in environment
  • Cardiovascular Function and Risk Factors
  • Perovskite Materials and Applications
  • Metamaterials and Metasurfaces Applications
  • Liver Disease Diagnosis and Treatment
  • Optical Network Technologies
  • Energy, Environment, Economic Growth
  • Sports, Gender, and Society
  • Mitochondrial Function and Pathology
  • Acupuncture Treatment Research Studies
  • Luminescence and Fluorescent Materials
  • Adipose Tissue and Metabolism
  • Autophagy in Disease and Therapy
  • Image Processing Techniques and Applications
  • Radioactivity and Radon Measurements

Xijing Hospital
2014-2025

Sun Yat-sen University
2022-2025

Air Force Medical University
2015-2025

Third Affiliated Hospital of Sun Yat-sen University
2022-2025

First Affiliated Hospital of Kunming Medical University
2025

Kunming Medical University
2025

Kunming University of Science and Technology
2025

China Agricultural University
2024

Beijing Institute of Technology
2023-2024

Shanghai Institute of Measurement and Testing Technology
2024

Rationale: Long-term exercise provides reliable cardioprotection via mechanisms still incompletely understood. Although traditionally considered a thermogenic tissue, brown adipose tissue (BAT) communicates with remote organs (eg, the heart) through its endocrine function. BAT expands in response to exercise, but involvement remains undefined. Objective: This study investigated whether small extracellular vesicles (sEVs) secreted by and their contained microRNAs (miRNAs) regulate...

10.1161/circresaha.121.320458 article EN Circulation Research 2022-04-07

The Western meat-rich diet is both high in protein and fat. Although the hazardous effect of a fat (HFD) upon liver structure function well recognized, whether co-presence intake contributes to, or protects against, HF-induced hepatic injury remains unclear. Increased branched chain amino acids (BCAA, essential compromising 20% total intake) reduces body weight. However, elevated circulating BCAA associated with non-alcoholic fatty disease injury. mechanisms responsible for this quandary...

10.1016/j.ebiom.2016.10.013 article EN cc-by-nc-nd EBioMedicine 2016-10-15

A large fraction of secondary aerosol particles are liquid–liquid phase-separated with an organic shell and inorganic core. This has the potential to regulate hygroscopicity such particles, significant implications for their optical properties, reactivity, lifetime. However, it is unclear how this phase separation affects hygroscopic growth particles. Here, we showed a variation in (e.g., 1.14–1.32 under relative humidity (RH) 90%) from forest urban atmosphere, which had different average...

10.1021/acs.est.1c05901 article EN Environmental Science & Technology 2021-12-12

Abstract Low‐dimensional organic–inorganic metal halides (OIMHs) have emerged as promising light emitters due to their broadband emission originating from self‐trapped excitons (STE), especially for Cu‐based OIMHs. Herein, Cu(I)‐based OIMH with a structure of (TPP) 2 Cu 4 I 6 ·2DMSO (TPP stays tetraphenylphosphonium, and DMSO – dimethyl sulfoxide) has been synthesized, both in form single crystals microcrystalline powder. This compound exhibits green peak at 515 nm full width half‐maximum 78...

10.1002/adfm.202310561 article EN Advanced Functional Materials 2023-11-21

The authors design a photonic crystal Mach-Zehnder interferometer by utilizing the self-collimated beams and bending splitting mechanisms of line defects. Using this interferometer, they investigate phase shift reflected transmitted over In addition, on basis intensity-asymmetric unidirectional-output design, demonstrate that such interferometers can function as an intensity detector or ultrafast optical switch when material is nonlinear.

10.1063/1.2746942 article EN Applied Physics Letters 2007-06-04

Abstract Background Microglia can not only detrimentally augment secondary injury but also potentially promote recovery. However, the mechanism underlying regulation of microglial phenotypes after stroke remains unclear. Methods Mice were subjected to middle cerebral artery occlusion for 60 min. At 3 days reperfusion, effects activation and suppression triggering receptor expressed on myeloid cells 2 immunocyte (n = 5), neurobehavioral scores 7), infarct volumes 8), neuronal apoptosis 7)...

10.1097/aln.0000000000001628 article EN Anesthesiology 2017-04-11

Abstract Hepatocellular carcinoma (HCC) is a severe disease with high mortality and global incidence. However, the interaction between gut microbiome combined immunotherapy for HCC yet unclear. In this prospective clinical study, patients unresectable who had not received systemic treatment previously were recruited. Fecal serum samples collected at baseline point before each subsequent administration as specified. Between 20 October 2019 2 February 2021, 61 screened eligibility, of whom 35...

10.1002/ijc.34118 article EN International Journal of Cancer 2022-05-17

Abstract Mesenchymal stem cells (MSCs) delivered into the post-ischemic heart milieu have a low survival and retention rate, thus restricting cardioreparative efficacy of MSC-based therapy. Chronic ischemia results in metabolic reprogramming heart, but little is known about how these changes influence implanted MSCs. Here, we found that excessive branched-chain amino acid (BCAA) accumulation, signature seen was disadvantageous to cardioprotection intramyocardially injected Discovery-driven...

10.1038/s41392-022-00971-7 article EN cc-by Signal Transduction and Targeted Therapy 2022-06-03

Abstract Databases of the morphological parameters fresh size‐resolved soot particles and their systematic comparisons among various combustion sources are important to trace aging process evaluate optical properties. Here, mixing state, effective density ( ρ eff ), monomer number diameter N d p fractal dimension D f ) from vehicle emissions (VE), biomass burning (BB), coal (CC), tunnel air (TA) urban (UA) were characterized based on electron microscopy observations analysis. We determined...

10.1029/2022jd037711 article EN Journal of Geophysical Research Atmospheres 2023-03-04

Abstract Mesenchymal stromal cell (MSC) implantation is a promising option for liver repair, but their poor retention in the injured milieu critically blunts therapeutic effects. The aim to clarify mechanisms underlying massive MSC loss post‐implantation and establish corresponding improvement strategies. primarily occurs within initial hours after into or under reactive oxygen species (ROS) stress. Surprisingly, ferroptosis identified as culprit rapid depletion. In ferroptosis‐...

10.1002/advs.202206439 article EN cc-by Advanced Science 2023-02-19

BACKGROUND: Myocardial mitochondrial dysfunction underpins the pathogenesis of heart failure (HF), yet therapeutic options to restore myocardial function are scarce. Epigenetic modifications DNA (mtDNA), such as methylation, play a pivotal role in modulating homeostasis. However, their involvement HF remains unclear. METHODS: Experimental models were established through continuous angiotensin II and phenylephrine (AngII/PE) infusion or prolonged ischemia/reperfusion injury. The landscape N 6...

10.1161/circulationaha.123.068358 article EN mit Circulation 2024-04-30

We investigate the effect of surface plasmon (SP) resonance on Goos–Hanchen (GH) spatial and angular shifts in reflection a light beam by considering an attenuated total structure containing graphene layer. In particular, we find giant GH for p-wave close to resonance. The can be controlled adjusting voltage applied via external gate. tunable provide alternative SP sensing scheme, which improves sensitivity sensors significantly.

10.1364/josab.31.002325 article EN Journal of the Optical Society of America B 2014-09-12

Abstract Organic–inorganic copper(I) halides (OICHs) have recently attracted great attentions for their unique optoelectronic properties. However, most of them poor stability and narrow excitation in UV region, which seriously hinder applications efficient white light‐emitting diodes (WLEDs). Herein, 0D (C 19 H 18 P) 2 Cu 4 I 6 with super broad‐band (300–500 nm) yellow emission the absolute photoluminescence quantum yield 87.4% is synthesized a quantity gram scale. Specifically, possesses...

10.1002/adom.202401050 article EN Advanced Optical Materials 2024-06-25

Abstract Ribosome biogenesis (RiboSis) and ribosomal stress are critical in tumor progression, positioning RiboSis as a promising therapeutic target for cancer treatment overcoming drug resistance. In this study, we examined the role of progression from hepatitis B virus (HBV) infection to HBV-related hepatocellular carcinoma (HCC), focusing specifically on nucleolar protein 9 (NOL9) its influence HCC pathogenesis response. Our findings showed that NOL9 was significantly upregulated tissues,...

10.1038/s41419-025-07393-7 article EN cc-by Cell Death and Disease 2025-02-15

The light absorption of black carbon (BC) particles is influenced by their mixing structures and coating compositions. Liquid-liquid phase separation (LLPS) an important microscopic phenomenon which can separate organic inorganic phases redistribute BC from the core (Icore) to (Ocoating). This study combines transmission electron microscopy a 3D modeling method—Electron-Microscope-To-BC-Simulation (EMBS) investigate how microphysical properties, such as compositions, Ocoating...

10.5194/egusphere-egu25-2512 preprint EN 2025-03-14

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, but effective treatments are lacking. Cardiac lymphatics play a crucial role in maintaining health by draining fluids and immune cells. However, their involvement HFpEF remains largely unexplored. METHODS: We examined cardiac lymphatic alterations mice comorbid obesity hypertension, tissues from patients HFpEF. Using genetically engineered mouse models various cellular...

10.1161/circulationaha.124.071741 article EN Circulation 2025-04-01
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