A5106405214- interferon and immune responses
- Adipokines, Inflammation, and Metabolic Diseases
- Diagnosis and treatment of tuberculosis
- Tuberculosis Research and Epidemiology
- Mosquito-borne diseases and control
- Ferroptosis and cancer prognosis
- Herpesvirus Infections and Treatments
- Protease and Inhibitor Mechanisms
- Cell death mechanisms and regulation
- RNA modifications and cancer
- Phagocytosis and Immune Regulation
- RNA Interference and Gene Delivery
- HIV Research and Treatment
- Signaling Pathways in Disease
- Cytomegalovirus and herpesvirus research
- Biomarkers in Disease Mechanisms
- HIV/AIDS Research and Interventions
- Virus-based gene therapy research
- HIV, Drug Use, Sexual Risk
- Mycobacterium research and diagnosis
- Wound Healing and Treatments
- Infectious Diseases and Tuberculosis
- Epigenetics and DNA Methylation
Baise University
2025
Soochow University
2025
Nanjing Medical University
2025
Shanghai Veterinary Research Institute
2024
Yangtze University
2024
Gene Tech (China)
2024
Brain Hospital of Jilin
2020-2023
Taian City Central Hospital
2018-2022
Weifang People's Hospital
2016
Tuberculosis (TB) remains a serious global public health problem in the present. TB also affects other sites (extrapulmonary tuberculosis, EPTB), and accounts for significant proportion of tuberculosis cases worldwide. In order to comprehensively understand epidemiology EBTB China, improve early diagnosis treatment, we conducted large-scale multi-center observational study assess demographic data prevalence common EPTB inpatients, further evaluate concurrent with Pulmonary (PTB) associations...
To investigate the effect of restricted access to clean needles and syringes on needle syringe sharing behavior like Human Immunodeficiency Virus (HIV) Hepatitis C (HCV) amongst people who inject drugs (PWID) in Baise, Guangxi province China, provide scientific evidence for formulating public health policies aimed at preventing HIV transmission. Using national unified questionnaire plan, from 2010 2019, snowball sampling was conducted among community drug users under sentinel surveillance...
Background Laryngeal cancer (LC) is characterized by high mortality and remains challenging in prognostic evaluation treatment benefits. Ubiquitin-related genes (UbRGs) are widely involved initiation progression, but their potential value LC unknown. Methods RNA-seq clinical data of were obtained from TCGA GEO. UbRGs that independently influenced the overall survival (OS) patients screened with differential expression, COX LASSO regression analyses. A signature was then established assessed...
Areca catechu, as a traditional Chinese medicine, contains high concentration of therapeutic compounds. However, the biosynthesis these compounds is largely unexplored. We present haplotype-resolved genome assembly and annotation for A. with chromosome-level sizes 2.45 Gb (Ac. Hap1) 2.49 Hap2). A comparative analysis haplotypes revealed significant divergence, including multiple Mb-level large inversions. Furthermore, catechu shared two whole duplications other palm plants its size had...
Tuberculosis (TB), a multisystemic disease with protean presentation, remains major global health problem. Although concurrent pulmonary tuberculosis (PTB) and extrapulmonary (EPTB) cases are commonly observed clinically, knowledge regarding PTB-EPTB is limited. Here, large-scale multicenter observational study conducted in China aimed to the epidemiology of by diagnostically defining TB types then implementing association rules analysis.The retrospective was at 21 hospitals 15 provinces...
Abstract Background Adiponectin, a protein hormone produced by adipose tissues, exhibits anti-inflammatory functions in various models. This study was investigated the effects of adiponectin on dextran sodium sulfate (DSS)-colonic injury, inflammation, apoptosis, and intestinal barrier dysfunction Caco-2 cell mice. Materials methods The results showed that DSS caused inflammatory response vitro vivo. Adiponectin injection alleviated colonic injury rectal bleeding Meanwhile, downregulated...
Parthanatos is distinct from caspase-dependent apoptosis in that it does not necessitate the activation of caspase cascades; Instead, relies on translocation Apoptosis-inducing Factor (AIF) mitochondria to nucleus, resulting nuclear DNA fragmentation. Newcastle Disease Virus (NDV) an oncolytic virus selectively targets and kills tumor cells by inducing cell apoptosis. It has been reported NDV triggers classic through mitochondrial pathway. In this study, we observed infection induced...
Visfatin has been reported to exert an important role in the development of atherosclerosis. However, mechanism that regulated expression not elucidated yet. This study aimed investigate effect SAA on regulation Visfatin, as well potential pathway. After RAW264.7 macrophages and primary monocytes were stimulated with SAA, mRNA protein was detected real-time PCR western blot, respectively. The concentration supernatant measured ELISA. Formyl peptide receptor 2 (FPR2) agonist (WKYMVm)...
To analyze the clinical characteristics, outcome and diagnosis of two cases imported children Zika virus infection in China.A retrospective analysis was performed on treatment with February 2016 Enping People's Hospital Guangdong.Two resided an affected area Venezuela, 8-year-old girl her 6 year-old brother. The main findings physical examination included following manifestations: fever, rash, conjunctivitis. rash first limited to abdomen, but extended torso, neck face, faded after 3-4 d....