Elizabeth Saunders
A5078546299- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Protist diversity and phylogeny
- Bacillus and Francisella bacterial research
- Bacteriophages and microbial interactions
- Biofuel production and bioconversion
- Identification and Quantification in Food
- Methane Hydrates and Related Phenomena
- Legume Nitrogen Fixing Symbiosis
- Aquaculture disease management and microbiota
- Insect Resistance and Genetics
- Metal Extraction and Bioleaching
- Anaerobic Digestion and Biogas Production
- Probiotics and Fermented Foods
- Enzyme Production and Characterization
- Vibrio bacteria research studies
- Microbial Fuel Cells and Bioremediation
- Cancer-related gene regulation
- Plant Disease Resistance and Genetics
- Microbial metabolism and enzyme function
- Nuclear Structure and Function
- Insect and Pesticide Research
- Bacterial Identification and Susceptibility Testing
- Glycosylation and Glycoproteins Research
- Microbial Metabolic Engineering and Bioproduction
Dartmouth College
2025
University of California, San Francisco
2023
Hampshire Hospitals NHS Foundation Trust
2022
Ohio University
2020
University of Surrey
2016
Los Alamos National Laboratory
2004-2013
Joint Genome Institute
2006-2012
Lawrence Livermore National Laboratory
2010
Bucknell University
2009
University of California, Davis
2007
Leguminous plants (such as peas and soybeans) rhizobial soil bacteria are symbiotic partners that communicate through molecular signaling pathways, resulting in the formation of nodules on legume roots occasionally stems house nitrogen-fixing bacteria. Nodule has been assumed to be exclusively initiated by binding bacterial, host-specific lipochito-oligosaccharidic Nod factors, encoded nodABC genes, kinase-like receptors plant. Here we show complete genome sequencing two symbiotic,...
Pseudomonas fluorescens are common soil bacteria that can improve plant health through nutrient cycling, pathogen antagonism and induction of defenses. The genome sequences strains SBW25 Pf0-1 were determined compared to each other with P. Pf-5. A functional genomic in vivo expression technology (IVET) screen provided insight into genes used by its natural environment an improved understanding the ecological significance diversity within this species.
ABSTRACT Bacterioplankton of the marine Roseobacter clade have genomes that reflect a dynamic environment and diverse interactions with plankton. Comparative genome sequence analysis three cultured representatives suggests cellular requirements for nitrogen are largely provided by regenerated ammonium organic compounds (polyamines, allophanate, urea), while typical sources carbon include amino acids, glyoxylate, aromatic metabolites. An unexpectedly large number genes predicted to encode...
Vibrio cholerae, the causative agent of cholera, is a bacterium autochthonous to aquatic environment, and serious public health threat. V. cholerae serogroup O1 responsible for previous two cholera pandemics, in which classical El Tor biotypes were dominant sixth current seventh respectively. Cholera researchers continually face newly emerging reemerging pathogenic clones carrying diverse combinations phenotypic genotypic properties, significantly hampered control disease. To elucidate...
Summary This paper describes the genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum ), which is model acetogenic bacterium that has been widely used for elucidating Wood–Ljungdahl pathway CO and 2 fixation. pathway, also known as reductive acetyl‐CoA allows (often called homoacetogenic) bacteria to convert glucose stoichiometrically into 3 mol acetate grow autotrophically using H electron donors an acceptor. Methanogenic archaea use this in reverse by converting methane...
Bacteria of the genus Deinococcus are extremely resistant to ionizing radiation (IR), ultraviolet light (UV) and desiccation. The mesophile radiodurans was first member this group whose genome completely sequenced. Analysis sequence D. radiodurans, however, failed identify unique DNA repair systems. To further delineate genes underlying resistance phenotypes, we report whole-genome a second species, thermophile geothermalis, which at its optimal growth temperature is as IR, UV desiccation...
Bacillus anthracis, cereus, and thuringiensis are closely related gram-positive, spore-forming bacteria of the B. cereus sensu lato group. While independently derived strains anthracis reveal conspicuous sequence homogeneity, environmental isolates exhibit extensive genetic diversity. Here we report sequencing comparative analysis genomes two members group, 97-27 subsp. konkukian serotype H34, isolated from a necrotic human wound, E33L, which was swab zebra carcass in Namibia. These strains,...
Chemoautotrophic endosymbionts are the metabolic cornerstone of hydrothermal vent communities, providing invertebrate hosts with nearly all their nutrition. The Calyptogena magnifica (Bivalvia: Vesicomyidae) symbiont, Candidatus Ruthia magnifica, is first intracellular sulfur-oxidizing endosymbiont to have its genome sequenced, revealing a suite capabilities. encodes major chemoautotrophic pathways as well for biosynthesis vitamins, cofactors, and 20 amino acids required by clam.
We report here a comparative analysis of the genome sequence Methanosarcina barkeri with those acetivorans and mazei. The M. is distinguished by having an organization that well conserved respect to other spp. in region proximal origin replication, interspecies gene similarities as high 95%. However, it disordered marked increased transposase frequency decreased synteny density distal semigenome. Of 3,680 open reading frames (ORFs) barkeri, 746 had homologs better than 80% identity both...
The marine bacterium Saccharophagus degradans strain 2-40 (Sde 2-40) is emerging as a vanguard of recently discovered group and estuarine bacteria that recycles complex polysaccharides. We report its complete genome sequence, analysis which identifies an unusually large number enzymes degrade >10 Not only this extraordinary range catabolic capability, many the exhibit unusual architecture including novel combinations catalytic substrate-binding modules. hypothesize these features are...
Background Methanomicrobiales is the least studied order of methanogens. While these organisms appear to be more closely related Methanosarcinales in ribosomal-based phylogenetic analyses, they are metabolically similar Class I Methodology/Principal Findings In improve our understanding this lineage, we have completely sequenced genomes two members order, Methanocorpusculum labreanum Z and Methanoculleus marisnigri JR1, compared them with genome a third, Methanospirillum hungatei JF-1....
Pollutants such as polychlorinated biphenyls and dioxins pose a serious threat to human environmental health. Natural attenuation of these compounds by microorganisms provides one promising avenue for their removal from contaminated areas. Over the past 2 decades, studies bacterium Sphingomonas wittichii RW1 have provided wealth knowledge about how bacteria metabolize chlorinated aromatic hydrocarbons. Here we describe finished genome sequence S. major findings its annotation.
ABSTRACT Modern methods to develop microbe-based biomass conversion processes require a system-level understanding of the microbes involved. Clostridium species have long been recognized as ideal candidates for involving and production various biofuels other industrial products. To expand knowledge base clostridial relevant current biofuel efforts, we sequenced genomes 20 spanning multiple genera. The majority fall within class III cellulosome-encoding V saccharolytic Thermoanaerobacteraceae...
Bacillus thuringiensis is an insect pathogen that widely used as a biopesticide (E. Schnepf, N. Crickmore, J. Van Rie, D. Lereclus, Baum, Feitelson, R. Zeigler, and H. Dean, Microbiol. Mol. Biol. Rev. 62:775-806, 1998). Here we report the finished, annotated genome sequence of B. Al Hakam, which was collected in Iraq by United Nations Special Commission (L. Radnedge, P. Agron, K. Hill, Jackson, L. Ticknor, Keim, G. Andersen, Appl. Environ. 69:2755-2764, 2003).
Haliangium ochraceum Fudou et al. 2002 is the type species of genus in myxococcal family 'Haliangiaceae'. Members are first halophilic myxobacterial taxa described. The cells follow a multicellular lifestyle highly organized biofilms, called swarms, they decompose bacterial and yeast as most myxobacteria do. fruiting bodies contain particularly small coccoid myxospores. H. encodes actin homologue identified genome. Here we describe features this organism, together with complete genome...
Kineococcus radiotolerans SRS30216 was isolated from a high-level radioactive environment at the Savannah River Site (SRS) and exhibits gamma-radiation resistance approaching that of Deinococcus radiodurans. The genome sequenced by U.S. Department Energy's Joint Genome Institute which suggested existence three replicons, 4.76 Mb linear chromosome, 0.18 plasmid, 12.92 Kb circular plasmid. Southern hybridization confirmed chromosome is linear. K. sequence examined to learn about physiology...
Whether Vibrio mimicus is a variant of cholerae or separate species has been the subject taxonomic controversy. A genomic analysis was undertaken to resolve issue. The genomes V. MB451, clinical isolate, and VM223, an environmental comprise ca. 4,347,971 4,313,453 bp encode 3,802 3,290 ORFs, respectively. As in other vibrios, chromosome I (C-I) predominantly contains genes necessary for growth viability, whereas II (C-II) bears adaptation change. C-I harbors many virulence genes, including...
Expanding access to medication for opioid use disorder (MOUD) people involved in the carceral system is a priority New Hampshire Department of Corrections (NHDOC), where more than 40% residents have an (OUD). NHDOC participated multi-site Justice Community Opioid Innovation Network (JCOIN) clinical trial, "Long-acting buprenorphine vs. naltrexone treatments criminal justice system-involved adults (EXIT-CJS)". We examine contributing factors expansion MOUD program from 2021 2023, including...
Veillonella parvula (Veillon and Zuber 1898) Prévot 1933 is the type species of genus in family Veillonellaceae within order Clostridiales. The V. interest because it frequently isolated from dental plaque human oral cavity can cause opportunistic infections. strictly anaerobic grows as small cocci which usually occur pairs. Veillonellae are characterized by their unusual metabolism centered on activity enzyme methylmalonyl-CoA decarboxylase. Strain Te3T, strain species, was intestinal...