A5010332832- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Nutrition and Health in Aging
- Sepsis Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- Drug-Induced Ocular Toxicity
- Hematological disorders and diagnostics
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Resistance in Bacteria
- Pneumonia and Respiratory Infections
- Liver physiology and pathology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac tumors and thrombi
- Soft tissue tumors and treatment
- Central Venous Catheters and Hemodialysis
- Liver Disease Diagnosis and Treatment
- COVID-19 and Mental Health
- Antibiotics Pharmacokinetics and Efficacy
- Patient Satisfaction in Healthcare
- Diet, Metabolism, and Disease
- High Altitude and Hypoxia
- Antibiotic Use and Resistance
- Urinary Tract Infections Management
- Respiratory Support and Mechanisms
Ministry of Health and Welfare
2019-2024
Taipei Hospital
2019-2024
Chinese People's Liberation Army
2021
National Taiwan University Hospital
2005-2019
Objective In this study, we evaluated the efficacy of hydroxychloroquine (HCQ) against coronavirus disease 2019 (COVID-19) via a randomized controlled trial (RCT) and retrospective study. Methods Subjects admitted to 11 designated public hospitals in Taiwan between April 1 May 31, 2020, with COVID-19 diagnosis confirmed by pharyngeal real-time RT-PCR for SARS-CoV-2, were at 2:1 ratio stratified mild or moderate illness. HCQ (400 mg twice d 200 daily 6 days) was administered. Both study...
Abstract Background Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aimed estimate the effects of hydroxychloroquine and chloroquine survival in from all available RCT evidence, published unpublished. Methods: Rapid meta-analysis ongoing, completed, discontinued RCTs treatment for any patients (protocol: https://osf.io/QESV4/ )....
Abstract Drug-resistant Klebsiella pneumoniae , especially extended-spectrum β-lactamase (ESBL)- and/or AmpC β-lactamase-producing strains, is an emerging problem worldwide. However, few data focusing on drug susceptibility of K. from community available. In this study, we analyzed 1016 isolates outpatients or those visiting emergency rooms collected during 2002–2012 Taiwan Surveillance Antimicrobial Resistance program. Significantly decreased susceptibilities to 3 rd generation...
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Increased resistance to third-generation cephalosporin (3GC) is a serious concern for community-onset Escherichia coli infection because this easily delays effective treatment. This study surveyed the current antimicrobial pattern among E. isolates that cause bacteremia, with special focus on prevalence of and risk factors 3GC resistance, determined poor outcomes patients bacteremia. retrospective was conducted at tertiary-care teaching hospital in Taiwan. All adult bacteremia between...
Central line (CL)-associated bloodstream infection (CLABSI) poses a major threat to patient safety and is associated with additional cost. This study investigated the sustained effect of multimodal interventions focusing on CL bundle improvement in adult intensive care units (ICUs) teaching hospital Taiwan.A before-after prospective was conducted 17 ICUs medical center northern Taiwan from January 2009 December 2013. Many that aimed facilitate implementation were initiated 2011. The...
Abstract Objective In this study, we evaluated the efficacy of hydroxychloroquine (HCQ) against coronavirus disease 2019 (COVID-19) via a randomized controlled trial (RCT) and retrospective study. Methods Subjects admitted to 11 designated public hospitals in Taiwan between April 1 May 31, 2020, with COVID-19 diagnosis confirmed by pharyngeal real-time RT-PCR for SARS-CoV-2, were at 2:1 ratio stratified mild or moderate illness. HCQ 400 mg twice d 200 daily 6 days administered. Both study...
The morbidity and mortality that accompany fatty liver may occur as a result of increased apoptosis hepatocytes decreased regeneration. We determined the effects high-fiber diet on hepatocyte regeneration after partial hepatectomy in rats with liver.Fatty was induced male Wistar weighing around 200 g through feeding high-fat for 4 weeks. were then randomly assigned to 3 groups received diet, normal or another Partial (around 70%) performed, killed 6, 24, 48, 72 hours hepatectomy. measured...