- Helicobacter pylori-related gastroenterology studies
- Genetic Associations and Epidemiology
- Clostridium difficile and Clostridium perfringens research
- Veterinary medicine and infectious diseases
- Genetics and Neurodevelopmental Disorders
- Eosinophilic Esophagitis
- Gastroesophageal reflux and treatments
- Hormonal and reproductive studies
- Bone Metabolism and Diseases
- Liver Disease Diagnosis and Treatment
- Wound Healing and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Dermatologic Treatments and Research
- Mesenchymal stem cell research
- Immunotherapy and Immune Responses
- Gastric Cancer Management and Outcomes
- Marine Invertebrate Physiology and Ecology
- Gut microbiota and health
- Gastrointestinal disorders and treatments
- Immune Cell Function and Interaction
- Attention Deficit Hyperactivity Disorder
- Sex and Gender in Healthcare
- Extracellular vesicles in disease
- Bladder and Urothelial Cancer Treatments
- Nanoplatforms for cancer theranostics
Jilin University
2024-2025
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry
2024-2025
Nanjing University of Science and Technology
2007-2025
Nanjing Medical University
2024-2025
Jiangnan University
2024-2025
Shenzhen Second People's Hospital
2024-2025
Shenzhen University Health Science Center
2025
Tianjin Chengjian University
2025
Yichang Central People's Hospital
2025
China Three Gorges University
2025
In the past few years, more and researchers have paid close attention to emerging field of delay tolerant networks (DTNs), in which network often partitions end-to-end paths do not exist nearly all time. To cope with these challenges, most routing protocols employ "store-carry-forward" strategy transmit messages. However, difficulty this is how choose best relay node determine time forward Fortunately, social relations among nodes can be used address problems. paper, we present a...
Abstract Objective Levofloxacin has been proposed to replace clarithromycin for Helicobacter pylori treatment. Seven‐ and 10‐day fluoroquinolone triple therapies have generally failed achieve cure rates of ≥90%, whereas 14‐day therapy achieved 95% success. The aim was assess the efficacy effect resistance on levofloxacin‐containing with or without addition bismuth. Design ‐positive patients functional dyspepsia healed peptic ulcers were randomized receive lansoprazole 30 mg b.i.d.,...
Summary Background Increasing Helicobacter pylori resistance has led to decreases in treatment effectiveness. Aim To test the effectiveness of susceptibility‐guided therapy vs a locally highly effective empiric modified bismuth quadruple for first‐line H region with high antimicrobial . Methods We compared 14‐day using multicentre superiority‐design trial, which randomised infected subjects 3:1 (a) therapies contained esomeprazole 20 mg and amoxicillin 1 g b.d. plus clarithromycin 500 mg,...
Abstract Psychiatric disorders are a group of complex psychological syndromes with high prevalence. It has been reported that gut microbiota dominant influence on the risks psychiatric through microbiota–brain axis. We extended classic gene set enrichment analysis (GSEA) approach to detect association between and diseases using published genome-wide study (GWAS) GWAS summary data. applied our real data sets five disorders, including attention deficiency/hyperactive disorder (ADHD), autism...
Radiotherapy (RT), a widely used clinical treatment modality for cancer, uses high-energy irradiation reactive oxygen species (ROS) production and DNA damage. However, its therapeutic effect is primarily limited owing to insufficient damage tumors harmful effects on normal tissues. Herein, core-shell structure of metal-semiconductors (Au@AgBiS2 nanoparticles) that can function as pyroptosis inducers both kill cancer cells directly trigger robust anti-tumor immune against 4T1 triple-negative...
Abstract The design of a low‐iridium‐loading anode catalyst layer with high activity and durability is key challenge for proton exchange membrane water electrolyzer (PEMWE). Here, the synthesis novel supported IrO 2 nanocatalyst tri‐layered structure, dubbed @TaO x @TaB that composed ultrasmall nanoparticles anchored on amorphous TaO overlayer TaB nanorods reported. composite electrocatalyst shows great stability toward oxygen evolution reaction (OER) in acid, thanks to its dual‐interface...
Abstract. There is evidence that climate change and human activities are changing ecohydrological systems, yet the complex relationships among ecological (normalized difference vegetation index, gross primary productivity, water use efficiency) hydrological variables (runoff, soil storage, groundwater etc.) remain understudied. This study develops a novel framework based on network analysis alongside satellite data in situ observations to delineate joint evolutions (phenomena) causal...
Reducing iridium packing density (gIr cm−3 electrode) represents a critical pathway to lower geometric Ir loading in proton exchange membrane water electrolyzers (PEMWEs), yet conventional approaches often cause performance issues of anode catalyst layer due decreased structural stability and limited electron/mass transport efficiency. Here we present deformable hollow IrOx nanospheres (dh‐IrOx) as structural‐engineered architecture that achieves an ultralow (20% IrO2 electrodes) while...
Abstract Background: The success rate of currently recommended 7‐day triple therapy with a PPI plus amoxicillin and clarithromycin has fallen into the unacceptable range. It is urgent to look for new strategy treat infection Helicobacter pylori . Aims: To observe efficacy therapy‐based, bismuth‐containing quadruple H. treatment. Methods: A total 160 patients functional dyspepsia who were Hp + randomly assigned two groups. Regimen: Omeprazole 20 mg, Amoxicillin 1.0 g, Clarithromycin 500 mg...
Abstract Background A reliably highly effective high‐dose proton‐pump inhibitor plus amoxicillin (dual Helicobacter pylori therapy) has remained elusive. We compared whether the addition of bismuth to dual therapy would improve efficacy as first‐line treatment. Methods This was an open‐label, randomized single‐center study 160 treatment‐naive patients with H. infection who were randomly assigned 14‐day esomeprazole 40 mg twice a day 1 g three times or without potassium citrate 600 (elemental...
Skin tissue expansion is a clinical procedure for skin regeneration to reconstruct cutaneous defects that can be accompanied by severe complications. The transplantation of mesenchymal stem cells (MSCs) has been proven effective in promoting and helping ameliorate complications; however, systematic understanding its mechanism remains unclear. MSCs from luciferase-Tg Lewis rats were intravenously transplanted into rat model identify homing transdifferentiation. To clarify underlying...
Abstract Background Helicobacter pylori ( H. ) eradication has become increasingly difficult especially for penicillin allergy patients. Aims To evaluate the efficacy of adding bismuth or high‐dose metronidazole to an regimen containing a proton‐pump inhibitor, clarithromycin, and in patients allergic penicillin. Methods Pilot study which penicillin‐allergic, treatment‐naive subjects were randomized (1:1) 14‐day esomeprazole (20 mg q12h), clarithromycin (500 high dose (400 q6h) with BECM...
The high prevalence of Helicobacter pylori (H pylori) infection in China results a substantial public health burden. Medical experts have not agreed on the best solution population intervention for this problem. We presented economic evaluation population-based H screen-and-treat strategy preventing gastric cancer, peptic ulcer disease (PUD), and nonulcer dyspepsia (NUD).Decision trees Markov models were developed to evaluate cost-effectiveness screening followed by eradication treatment...
The efficacy of nanoradiosensitizers in cancer therapy has been primarily impeded by their limited accessibility to radioresistant cells residing deep inside tumor tissues. failure report response radiotherapy generally delays adjustment the treatment schedule and sets up another substantial obstacle clinical success. Here, we develop a nanopomegranate (RNP) platform that not only visualizes radiosensitivities but also potentiates tissue via elevated passive diffusion active transcytosis....
Abstracts Background There have been reports of Helicobacter pylori ( H. ) in the oral cavity and it has suggested that may be a reservoir for reflux from stomach. High-throughput sequencing was used to assess structure composition microbiota communities individuals with or without confirmed infection. Methods Saliva samples were obtained 34 infected 24 uninfected subjects. Bacterial genomic DNA extracted examined by amplification 16S rDNA V3-V4 hypervariable regions followed bioinformatics...
The giant jellyfish Nemopilema nomurai sting can cause local and systemic reactions; however, comparative analysis of the tentacle extract (TE) nematocyst venom (NV), its toxicity, mechanism, potential intervention are still limited. This study compared from TE NV for their composition, efficacy in vitro vivo used RAW264.7 cells ICR mice. A total 239 225 toxin proteins were identified by proteomics, respectively. Pathological revealed that caused heart liver damage through apoptosis,...
The multi-directional and spatial variations of ground motions have been recognized as common factors contributing to the unfavorable response long-span bridges for decades. However, they are not typically considered in seismic design due their complex influence. This study investigates influences tri-directional excitation wave-passage effect with different apparent wave velocities on a reinforced concrete deck-type arch bridge using shaking table tests. A scaled model at 1:30 ratio was...