A5075789888- Ferroptosis and cancer prognosis
- Advanced battery technologies research
- Electrocatalysts for Energy Conversion
- Glioma Diagnosis and Treatment
- RNA modifications and cancer
- Autophagy in Disease and Therapy
- Electrochemical Analysis and Applications
- Cancer, Hypoxia, and Metabolism
- Cancer Mechanisms and Therapy
- Cancer, Lipids, and Metabolism
- Conducting polymers and applications
- Epigenetics and DNA Methylation
- Catalytic Processes in Materials Science
- Plant biochemistry and biosynthesis
- Drug Transport and Resistance Mechanisms
- Advanced Photocatalysis Techniques
- RNA Interference and Gene Delivery
- Genetic and Kidney Cyst Diseases
- Fuel Cells and Related Materials
- Nanoparticle-Based Drug Delivery
- MicroRNA in disease regulation
- Nanoplatforms for cancer theranostics
- Genetics and Neurodevelopmental Disorders
- Histone Deacetylase Inhibitors Research
- Mitochondrial Function and Pathology
Guangxi University
2025
China Pharmaceutical University
2024-2025
Guangxi University of Science and Technology
2022-2024
Wuhan University
2021-2023
Renmin Hospital of Wuhan University
2021-2023
Chongqing University of Technology
2021
University of Stuttgart
2011
Zhejiang University of Science and Technology
2007
Glioblastoma multiforme (GBM) is the most common and fatal primary malignant central nervous system tumor in adults. Although there are multiple treatments, median survival of GBM patients unsatisfactory, which has prompted us to continuously investigate new therapeutic strategies, including drugs drug delivery approaches. Ferroptosis, a kind regulated cell death (RCD), been shown be dysregulated various tumors, GBM. Fatostatin, specific inhibitor sterol regulatory element binding proteins...
Lower-grade glioma (LGG) is a common malignant primary tumour in the central nervous system, and most patients eventually develop highly aggressive gliomas despite comprehensive traditional treatment. Tumour molecular subtypes prognostic biomarkers play crucial role LGG diagnosis Therefore, identification of novel for predicting prognosis glioma. Immunogenic cell death (ICD) defined as regulated that sufficient to activate adaptive immune response immunocompetent hosts. The combination ICD...
Glioblastoma (GBM) is the most common and fatal primary tumor in central nervous system (CNS). Due to existence of blood-brain barrier (BBB), therapeutics cannot efficiently reach tumors brain, as a result, they are unable be used for effective GBM treatment. Accumulating evidence shows that delivery form nanoparticles (NPs) may allow crossing BBB
Photocatalytic membranes hold significant potential for promoting pollutant degradation and reducing membrane fouling in filtration systems. Although extensive research has been conducted on the independent design of photocatalysts or materials to improve their catalytic performance, complex structures interface mechanisms, as well insufficient light utilization, are still often overlooked, limiting overall performance improvement photocatalytic membranes. This work provides an overview...
Abstract Background Mitochondria represent a major source of reactive oxygen species (ROS) in cells, and the direct increase ROS content is primary cause oxidative stress, which plays an important role tumor proliferation, invasion, angiogenesis, treatment. However, relationship between mitochondrial stress-related genes glioblastoma (GBM) remains unclear. This study aimed to investigate value mitochondria prognosis therapeutic targets GBM. Methods We retrieved from several public databases....
Co 1 Ni 6 CH exhibits a good OER activity (η 50 = 256 mV, 51 mV/dec) and stability in M KOH with partial phase transformation. Fe impurity electrolyte can provide more active sites, improve electronic conductivity, promote stability.
WHO 2/3 glioma is a common intracranial tumor that seriously affects the quality of life and survival time patients. Previous studies have shown tricarboxylic acid (TCA) cycle closely related to occurrence development glioma, while recent cuproptosis, novel programmed death pathway, inhibition TCA cycle. In our study, eight ten cuproptosis-related genes (CRGs) were found be differentially expressed between normal tissues. Through LASSO algorithm, cuproptosis-associated risk signatures...
The promotion effect of citrate anions (CA) on OER activity is considered. CA intercalation could accelerate the structure reconstruction to re-form catalytically active Ni(Fe)OOH.
Gliomas are one of the most frequent types nervous system tumours and have significant morbidity mortality rates. As a result, it is critical to fully comprehend molecular mechanism glioma predict prognosis target gene therapy. The goal this research was discover hub genes investigate their prognostic diagnostic usefulness. In study, we collected mRNA expression profiles clinical information from patients in TCGA, GTEx, GSE68848, GSE4920 databases. WGCNA differential analysis identified 170...
Introduction Uveal melanoma (UM) is the most common primary intraocular malignant tumor in adults, and main treatment for UM currently surgery plaque brachytherapy. highly susceptible to metastasis, which eventually occurs nearly half of all patients; once metastasis occurs, patients have a poor prognosis condition difficult treat. Therefore, identification new effective biomarkers vital application therapeutic strategies. Immunogenic cell death (ICD) type regulatory that activates adaptive...
This study conducts a systematic investigation into the catalytic mechanism of norcoclaurine synthase (NCS), key enzyme in biosynthesis tetrahydroisoquinolines (THIQs) with therapeutic applications. By integration LiGaMD and DFT calculations, reaction pathway NCS is mapped, providing detailed insights its activity selectivity. Our findings underscore critical role E103 substrate capture reveal hitherto unappreciated influence nonpolar residues M183 L76 on tunnel dynamics. A prominent...
Three-dimensional porous carbon materials with moderate heteroatom-doping have been extensively investigated as promising electrode for energy storage. In this study, we fabricated a 3D cross-linked chitosan-dicyandiamide-VOSO4 hydrogel using polymerization process. After pyrolysis at high temperature, VOx/N-doped nanosheet hybrids (3D VNCN) were obtained. The unique skeleton, abundant doping elements, and presence of VOx VNCN pyrolyzed 800 °C VNCN-800) ensured excellent electrochemical...
Glioblastoma multiforme (GBM) is the most common and fatal primary malignant brain tumour in adults. The average survival time of patients after diagnosis only 12-15 months. And its characteristics excessive proliferation apoptosis evasion play a crucial role poor prognosis patients. Therefore, it worth investigating molecular mechanism GBM to find an effective therapeutic target overcome dilemma. In current study, Transmembrane BAX inhibitor motif containing 1 (TMBIM1) was highly expressed...
The optical properties of PET have always been a problem that related research has trying to break through. In the previous work, we modified by adding PSLDH (phosphate antioxidant) obtain film with excellent properties. Through non-isothermal crystallization kinetic analysis PET, hope verify conclusion effect addition on PET. and were tested DSC at different cooling rates. process was calculated analyzed Jeziorny Mo methods activation energy Kissinger Friedman analyzing curves. results show...
<h2>Abstract</h2> Glioblastoma multiforme (GBM) is the most common intracranial malignant tumor and notorious for its poor prognosis. An important element in short overall survival of GBM patients lack understanding pathogenesis progression deficiency biomarkers that can be used early diagnosis therapeutic sensitivity monitoring. Studies have shown transmembrane protein 2 (TMEM2) participated tumorigenesis various human tumors, including rectal breast cancers. Although Qiuyi Jiang et al....