Patrizia Agostinis
A5091862786- Autophagy in Disease and Therapy
- Endoplasmic Reticulum Stress and Disease
- Photodynamic Therapy Research Studies
- Nanoplatforms for cancer theranostics
- Immunotherapy and Immune Responses
- Cancer, Hypoxia, and Metabolism
- Phagocytosis and Immune Regulation
- Cell death mechanisms and regulation
- Mitochondrial Function and Pathology
- Cancer Immunotherapy and Biomarkers
- Ubiquitin and proteasome pathways
- Cancer Research and Treatments
- Skin Protection and Aging
- Immune Cell Function and Interaction
- Immune cells in cancer
- Heme Oxygenase-1 and Carbon Monoxide
- Adenosine and Purinergic Signaling
- Retinal Diseases and Treatments
- RNA regulation and disease
- Melanoma and MAPK Pathways
- Cellular transport and secretion
- RNA Interference and Gene Delivery
- Redox biology and oxidative stress
- Calcium signaling and nucleotide metabolism
- CAR-T cell therapy research
KU Leuven
2016-2025
VIB-KU Leuven Center for Cancer Biology
2019-2025
University of Illinois Chicago
2023-2024
Ashland (United States)
2023-2024
Council of Science Editors
2022-2024
Cezanne (Italy)
2019-2024
Robert Koch Institute
2018-2024
Walter de Gruyter (Germany)
2018-2024
National Agricultural Library
2024
Baidu (China)
2024
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, on this topic has continued to accelerate, and many new scientists have entered field. Our knowledge base relevant technologies also been expanding. Accordingly, it is important update these monitoring autophagy different organisms. Various reviews described range assays that used purpose. Nevertheless, there continues be confusion regarding acceptable methods measure autophagy, especially...
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, on this topic has continued to accelerate, and many new scientists have entered field. Our knowledge base relevant technologies also been expanding. Accordingly, it is important update these monitoring autophagy different organisms. Various reviews described range assays that used purpose. Nevertheless, there continues be confusion regarding acceptable methods measure autophagy, especially...
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered field. Our knowledge base relevant new technologies also been expanding. Thus, it is important to formulate on a regular basis updated monitoring autophagy different organisms. Despite numerous reviews, there continues be confusion regarding acceptable methods evaluate autophagy, especially multicellular...
Autophagy and apoptosis are two important interconnected stress-response mechanisms. However, the molecular interplay between these pathways is not fully understood. To study fate function of autophagic proteins at onset apoptosis, we used a cellular model system in which autophagy precedes apoptosis. IL-3 depletion Ba/F3 cells caused caspase (casp)-mediated cleavage Beclin-1 PI3KC3, crucial components autophagy-inducing complex. We identified casp sites Beclin-1, TDVD(133) DQLD(149), yields...
Successful immunogenic apoptosis in experimental cancer therapy depends on the induction of strong host anti-tumor responses. Given that tumors are often resistant to apoptosis, it is important identify alternative molecular mechanisms elicit cell death. We have developed a genetic model which direct dimerization FADD combined with inducible expression RIPK3 promotes necroptosis. report necroptotic cells release damage-associated patterns and promote maturation dendritic cells, cross-priming...