A5036980336- Maternal and fetal healthcare
- Liver Diseases and Immunity
- Uterine Myomas and Treatments
- Liver Disease Diagnosis and Treatment
- Ectopic Pregnancy Diagnosis and Management
- Reproductive System and Pregnancy
- Pediatric Hepatobiliary Diseases and Treatments
- Endometriosis Research and Treatment
- Pregnancy and preeclampsia studies
- Preterm Birth and Chorioamnionitis
- Urticaria and Related Conditions
- Gallbladder and Bile Duct Disorders
- Urological Disorders and Treatments
- Immunotherapy and Immune Responses
- Reproductive tract infections research
- Diabetes and associated disorders
- Gestational Trophoblastic Disease Studies
- biodegradable polymer synthesis and properties
- MRI in cancer diagnosis
- Cardiovascular Issues in Pregnancy
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Electrolyte and hormonal disorders
- Minimally Invasive Surgical Techniques
- Infant Development and Preterm Care
- Toxoplasma gondii Research Studies
Nagasaki Medical Center
2012-2024
Sapporo Toho Hospital
2024
Teine Keijinkai Hospital
2017-2023
National Hospital Organization
2011-2016
Japanese Red Cross Hadano Hospital
2014-2016
Kanazawa Medical Center
2014-2016
Koto Hospital
2016
Showa University
2011-2016
Showa University Koto Toyosu Hospital
2016
Utsunomiya University
2012
A previous genome-wide association study (GWAS) performed in 963 Japanese individuals (487 primary biliary cholangitis [PBC] cases and 476 healthy controls) identified TNFSF15 (rs4979462) POU2AF1 (rs4938534) as strong susceptibility loci for PBC. In this study, we GWAS additional 1,923 (894 PBC 1,029 controls), combined the results with data. This GWAS, together a subsequent replication an independent set of 7,024 (512 6,512 PRKCB (rs7404928) novel locus (odds ratio [OR] = 1.26, P 4.13 ×...
Organic–inorganic hybrid microcapsules (AP-capsules) were fabricated by sequential preparation of calcium alginate (Alg-capsules), followed the addition Alg-capsules to an aqueous solution 3-aminopropyltriethoxysilane (APTES) in mild conditions without use any catalyst. Results showed that shell thickness AP-capsules was found vary with time during APTES incorporation onto Alg-capsules, suggesting dependent on amount CaCl2 contained initially core as well reaction time. A model enzyme,...
Prepregnancy myomectomy is effective for the treatment of infertility or prevention obstetric complications and usually performed with laparoscopy. However, pregnancies following have risks complications, especially in cases uterine cavity breaches, but evidence remains unclear. We investigated how breach laparoscopic influenced occurrence complications.One hundred eighty women who underwent a cesarean section from 2014 to 2020 were included. They divided into two groups: 25 group 155...
Abstract Our aim was to evaluate the association between ritodrine and magnesium sulfate (MgSO 4 ) occurrence of neonatal hyperkalemia or hypoglycemia among late preterm infants in a retrospective cohort study. We used nationwide obstetrical database from 2014. A total 4,622 live born at 32–36 gestational weeks participated. Fourteen risk factors based on both clinical relevance univariate analysis were adjusted multivariable logistic regression analyses. Neonatal occurred 7.6% (284/3,732)...
Anti-β2-glycoprotein I/HLA-DR (anti-β2GPI/HLA-DR) antibody has been reported to be associated with antiphospholipid syndrome and recurrent pregnancy loss (RPL). We conducted a prospective multicenter cross-sectional study aimed at evaluating whether the anti-β2GPI/HLA-DR is adverse obstetric outcomes RPL. From 2019 2021, serum levels (normal, <73.3 U) were measured in 462 women RPL, 124 fetal growth restriction (FGR), 138 hypertensive disorders of (HDP), 71 preterm delivery before 34...
Abstract Aim: The present observational study aimed to clarify the effects of sleep disorders on threatened premature delivery, especially preterm uterine contraction. Methods: participants included 122 healthy singleton pregnant women. Pittsburgh quality index was used evaluate during previous month at initial examination and 16, 24, 32 weeks gestation; scores >5 indicate poor sleep. Threatened delivery defined as contraction >6 times/h requiring tocolytic therapy before 37 gestation....
Although various perinatal complications have been reported to be increased in the pregnant patients with adenomyosis, it is not clear what type of adenomyosis more likely cause obstetric complications. In this study, we focused on positional relationship between placenta and lesion evaluating prognosis adenomyosis.This retrospective cohort study was carried out 1 January 2005 31 December 2019 a single institution. Adenomyosis diagnosed by magnetic resonance imaging (MRI) and/or transvaginal...
Surgical strategies for the treatment of uterine artery pseudoaneurysm (UAP) include transarterial embolization and ultrasound-guided low-dose thrombin injection. Such strategies, however, have limitations risk ischemic damage to uterus. We report a case UAP treated with new hysteroscopic laparoscopic technique. A 29-year-old G1P0 woman spontaneous abortion was transferred present institution because hemorrhagic shock. diagnosed ruptured on transvaginal ultrasound color Doppler. Emergency...
Postlaparoscopic shoulder pain (SP), mainly caused by pneumoperitoneum with CO2 , sometimes suffers patients. This study was aimed to analyze the backgrounds of SP after gynecologic laparoscopy clarify risk SP.We analyzed answers questionnaire about degree from 696 patients undergoing laparoscopic surgery since 2014-2018. The asks numeric rating scale 0 10, before and 3 days operation. We defined cases in which postoperative score elevated more than three compared preoperative as SP(+)....
The objective of this study was to observe the influence laparoscopic adenomyomectomy on perinatal outcomes.The retrospective cohort included 43 pregnant cases with adenomyosis who did not undergo surgery before pregnancy (nonsurgery group; 26 cases) and (surgery 17 cases). To evaluate impact outcomes, nine obstetric complications including preterm delivery, hypertensive disorder pregnancy, placental malposition, oligohydramnios, gestational diabetes mellitus, uterine rupture, abruptio...
We aimed to clarify the accuracy of pregnant women's knowledge and understanding regarding infectious disease screening in early pregnancy roles that should be played by health care providers promoting women their children.A cross-sectional questionnaire survey was conducted 25 hospitals across Japan from May 2018 September 2019. compared agreement rates results for hepatitis B virus (HBV), C (HCV), syphilis, human T-cell leukemia virus-1 (HTLV-1), cervical cytology medical records women....
Abstract Purpose It is unknown whether surgery for endometriosis or recurrence of affects obstetric outcomes. Methods A total 208 pregnant women with a history were analyzed. Patients who had endometriomas >3 cm and no laparoscopic defined as non‐surgery group ( n = 60), while those 148) group. We investigated the outcomes in patients according to without postoperative time from pregnancy. Results Among 177 cases on‐going pregnancy, group, there lower prevalence placenta previa compared...
Abstract A 23‐year‐old woman, gravida 1, para was transferred to our hospital with acute lower abdominal pain and vital signs consistent shock. Her urine concentration of human chorionic gonadotrophin 8000 mIU/mL. Transvaginal ultrasound revealed an echo‐free space mosaic echo pattern in the right adnexal area no gestational sac uterus. With a preoperative diagnosis ruptured ectopic pregnancy, emergency laparotomy performed. The rectouterine pouch filled many clots containing small amounts...
This prospective cohort study aimed to evaluate the performance of Flora select™ (FS), a newly developed real-time PCR test, for assessment vaginal microbiome during early pregnancy. Five hundred and fifty-six pregnant women underwent examinations FS, Nugent score-a Gram-staining scoring system diagnosis bacterial vaginosis (BV)-and conventional culture between 8 weeks 12 gestational weeks. scores 0-3, 4-6, ≥7 were found in 469 (84.2%), 41 (7.4%), 47 (8.5%) women, respectively. Relative...