A5100382861- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Thyroid Cancer Diagnosis and Treatment
- Diabetes Treatment and Management
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Thyroid Disorders and Treatments
- Cardiac Arrhythmias and Treatments
- Cardiac tumors and thrombi
- Diabetes Management and Research
- Head and Neck Anomalies
- Atrial Fibrillation Management and Outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Metabolism, Diabetes, and Cancer
- Probiotics and Fermented Foods
- Pituitary Gland Disorders and Treatments
- Cardiac Structural Anomalies and Repair
- Osteoarthritis Treatment and Mechanisms
- Radiomics and Machine Learning in Medical Imaging
- Microbial Metabolites in Food Biotechnology
- Antiplatelet Therapy and Cardiovascular Diseases
- Adrenal and Paraganglionic Tumors
Pukyong National University
2014-2025
Catholic University of Korea
2014-2024
Daejeon St. Mary's Hospital
2011-2024
Uijeongbu St. Mary's Hospital
2011-2022
Korea Research Institute of Bioscience and Biotechnology
2021
Seoul St. Mary's Hospital
2014-2020
Korea Institute of Science and Technology
2020
Ulsan University Hospital
2018-2019
University of Ulsan
2018-2019
Ulsan College
2018-2019
We analyzed the sonographic characteristics of thyroid nodules and assessed diagnostic value ultrasonography in order to distinguish between benign malignant lesions terms management nodules.We retrospectively features 580 patients who had been examined with fine-needle aspiration cytology or underwent surgery for a nodule. The that suggested malignancy include microcalcifications, an irregular microlobulated margin, marked hypoechogenicity, shape was taller than it wide. presence one more...
The association between autoimmune thyroiditis (AIT) and thyroid cancer is still not clear despite many previous reports. This study investigated whether serologic antibodies are predictive of in patients with nodules.We retrospectively reviewed records nodules evaluated by ultrasonography-guided fine-needle aspiration cytology at our institution January 2006 December 2008. Thyroid autoimmunity was assessed measuring thyroglobulin antibody (TgAb) peroxidase (TPOAb). final outcome deciding a...
We investigated the association between diabetes duration and extent severity of coronary artery disease (CAD) as well long-term clinical outcomes using computed tomography angiography (CCTA) in asymptomatic type 2 diabetic patients.We analysed 933 patients without known CAD who underwent CCTA. Patients were divided into three groups according to diabetes: <5 years, 5-10 ≥10 years. Stenosis by CCTA was scored none (0%), non-obstructive (1-49%), or obstructive (≥50%) for each segment. For...
<h3>Objective</h3> β-blockers are the standard treatment for myocardial infarction (MI) based on evidence from pre-thrombolytic era. The aim of this study was to examine effect β-blocker in patients with acute MI and preserved systolic function era percutaneous coronary intervention (PCI). <h3>Methods</h3> We analysed a multicentre registry identified 3019 who presented between 2004 2009. Patients were treated PCI, had left ventricular EFs ≥50% according echocardiograms that performed during...
Fermented bamboo (also known as Ngwopo) is a traditional food item among the indigenous population living in south-east of Bangladesh. Though fermented foods harbour significant number probiotics and enzyme-producing bacteria, there lack research on isolating beneficial bacteria from native products Thus, considering extensive utilisation cellulase enzymes probiotics, our study was conducted with objective characterizing cellulase-producing performing crude enzyme activity assay. The sample...
Vibrio anguillarum threatens fish and larval farming industries human health worldwide. The identification of bacterial adaptation responses to stress due environmental changes is vital for establishing a response strategy pathogenic Vibrio. Previously, short-chain dehydrogenase/reductase (SDR) was identified on chromosome II the multichromosomal V. anguillarum. In this study, comparison SDR enzyme FabG-1b (encoded I responsible β-ketoacyl acyl carrier protein (ACP) reductase in fatty acid...
The no-reflow phenomenon is a potential complication of primary percutaneous coronary intervention (PCI). Predictors the and impact on long-term mortality remain unclear.Two thousand seventeen patients with ST-segment elevation myocardial infarction (STEMI) who had undergone PCI were consecutively enrolled in multicentre Acute Myocardial Infarction registry Korea. was diagnosed basis angiographic criteria. outcome all-cause mortality.The 262 (13.0%). Independent predictors older age, high...
OBJECTIVE We investigated the efficacy of coronary computed tomography angiography (CCTA) in predicting long-term risks asymptomatic patients with type 2 diabetes and compared it traditional risk factors. RESEARCH DESIGN AND METHODS analyzed 933 who underwent CCTA. Stenosis was considered obstructive (≥50%) each artery segment using The extent severity scores for disease (CAD) were evaluated. primary end point major adverse cardiovascular events (MACE), including all-cause mortality,...
Hypothyroidism has been known to be associated with hyperlipidemia, endothelial dysfunction and atherosclerosis. Elevation of thyroid-stimulation hormone (TSH) is a gold standard detect these conditions. However, no large studies have investigated the association between TSH elevation long-term clinical outcomes in patients acute myocardial infarction (AMI).Hypothyroidism higher mortality AMI.A total 4748 AMI undergoing percutaneous coronary intervention (PCI) drug-eluting stents were...
Background: The roles of soluble and endogenous secretory receptors for advanced glycation endproducts (sRAGE esRAGE, respectively) in plaque vulnerability are unknown patients with acute myocardial infarction (AMI). Methods Results: We enrolled 54 AMI (27 had type 2 diabetes mellitus [DM]) who undergone primary percutaneous coronary intervention, controls were matched age, gender the presence DM. Plasma levels s/esRAGE matrix metalloproteinase (MMP)-9 measured at time angiography. There no...
Background The natural course of cytologically benign thyroid nodules remains unclear. aim this study was to evaluate whether ultrasonographic (US) changes are associated with in nodule volume during follow-up. Methods We retrospectively reviewed over 4 years clinical records patients as confirmed by fine needle aspiration (FNA). In total, 186 202 were included for study. assessed and examined the cystic portion well four US features (echogenicity, margin, calcification pattern, shape)....
Background and Objectives:We performed this study to evaluate the common carotid artery intima-media thickness (CCA IMT), its correlation with several clinical variables, including 10 year coronary heart disease (10 Yr CHD) risk in both healthy hyperlipidemic hypertensive (HH) Koreans. Subjects Methods:This was a multi-centered prospective epidemiological study. The population consisted of 227 subjects without factors, exception age (mean 49 years old, 114 males), 243 HH 51 120 males). IMT...
Background and Aim: Patients with chronic kidney disease (CKD) often have subclinical hypothyroidism.However, few reports investigated changes in the status of hypothyroidism CKD patients its clinical significance progression.Methods: We included 168 nondialysis-dependent stages 2-4.The normalization during follow-up was assessed, association between transitions hypothyroid rate decline estimated glomerular filtration (eGFR) investigated.Results: At baseline, 127 were euthyroid 41 (24.4%)...
<b><i>Background/Aims:</i></b> Atrial fibrillation (AF) often coexists with acute myocardial infarction (AMI), and chronic kidney disease (CKD) is a major risk for AMI. However, the combined impact of CKD AF on mortality morbidity in AMI population has not been determined. <b><i>Methods:</i></b> Between January 2004 December 2009, total 4,738 patients were enrolled prospectively. Patients divided into four groups according to status AF. The...
In the present study, probiotic properties of Pediococcus acidilactici FS2 isolated from Korean traditional food, gajami-sikhae (fermented flounder), and effect its oral administration on reduction in blood cholesterol mice were investigated. Analysis probiotics properties, such as acid bile resistance, antibiotic cell adhesion, antioxidant activity, antibacterial enzyme demonstrated that is a potential candidate. showed high growth rate when isomalto-oligosaccharides (IMO) used prebiotic....
Muscular Sarcoidosis Detected by F-18 FDG PET/CT in a Hypercalcemic PatientSarcoidosis is systemic granulomatous disease of unknown etiology that involves many organs, occasionally mimicking malignancy.We herein report 50-yr-old woman muscular sarcoidosis chronic myopathic type, manifested hypercalcemia and muscle wasting.Besides insignificant hilar lymphadenopathy, her was confined to generalized atrophic muscles therefore, alone among conventional imaging studies provided diagnostic clues...
The impact of the CYP2C19*17 polymorphism on clinical outcome in Asians undergoing percutaneous coronary intervention (PCI) is unknown. We sought to assess long-term risk for adverse events 2188 Korean patients taking clopidogrel after PCI. prevalence allele [*wt/*17: 2.4% (n = 53), *17/*17: 0%] was very low. 2-year cumulative event rates bleeding [*wt/*17 vs. *wt/*wt: 2 2.3%; adjusted hazard ratio (HR), 1.23; 95% confidence interval (CI), 0.16-9.45], stent thrombosis (2 1.1%; HR, 3.98; CI,...
The mechanism of development the ovarian follicles has been largely unknown. We performed an immunohistochemical (IHC) study to determine follicular expressions c-kit, SCF, and inhibin-alpha at different developmental stages in mouse ovary. Ovaries were obtained from 14 16 days post coitum 2, 7, 21 partum (dpp) mice. IHC for was carried out. c-Kit SCF expressed on oogonia regardless stage. Immunoreactive c-kit antigens oocytes primordial primary neonate ovaries. In dpp ovary, expression...
We describe the secretory expression and immunogenicity of recombinant HAV (hepatitis A virus) structural polypeptide VP1 from stably transformed Drosophila melanogaster S2 (Schneider 2) cells. Southern-blot analysis indicated that cells contained multiple copies gene in genome. Recombinant was secreted into a culture medium with molecular mass 42-49 kDa. maximum production level 6.24 mg VP1/litre obtained T-flask 5 days after induction 0.5 mM CuSO4. The protein elicited specific IgA small...
In cartilage tissue engineering from mesenchymal stem cells, it is important to suppress hypertrophy produce a neocartilage with stable phenotypes of hyaline articular (AC). The aim this study was develop and test the usefulness functional chondrogenic scaffolds that serve purpose suppression. PD98059-impregnated poly(lactic-co-glycolic acid) (PLGA) scaffold fabricated compared transforming growth factor (TGF)-β2-immobilized scaffold. PD98059 continuously released over 140 days in contrast...
Hyun Kyung Chung, Eu Jeong Ku, Won Sang Yoo, Yea Eun Kang, Kyeong Jin Kim, Bo Tae-Yong Young Joo Park, Chang Ho Ahn, Jee Hee Yoon, Lee, Jong Min Eui Dal Jung, Jae Hoon Yun Bae Ka Yi, Ho-Cheol Kang and Do Joon Park. Int J Thyroidol 2023;16:32-50. https://doi.org/10.11106/ijt.2023.16.1.32