A5053651027- Lung Cancer Research Studies
- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Cancer Genomics and Diagnostics
- Rice Cultivation and Yield Improvement
- RNA modifications and cancer
- Colorectal Cancer Treatments and Studies
- Cancer therapeutics and mechanisms
- Lung Cancer Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Effects of Radiation Exposure
- Immune cells in cancer
- Neuroendocrine Tumor Research Advances
- Cancer-related molecular mechanisms research
- Plant responses to water stress
- Cancer Cells and Metastasis
- Cancer-related Molecular Pathways
- Climate change impacts on agriculture
- Brain Metastases and Treatment
- Nonmelanoma Skin Cancer Studies
- Glioma Diagnosis and Treatment
- Cancer Treatment and Pharmacology
- Colorectal and Anal Carcinomas
- Nanoplatforms for cancer theranostics
- interferon and immune responses
Shanxi Agricultural University
2025
Xinzhou Teachers University
2025
Tsinghua University
2023-2024
Shanghai Jiao Tong University
2024
Soochow University
2024
Sir Run Run Shaw Hospital
2024
Zhejiang University
2014-2024
Beijing Tsinghua Chang Gung Hospital
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2023
Xiangyang Central Hospital
2023
Tumor-associated macrophages (TAMs) generally display an immunosuppressive M2 phenotype and promote tumor progression metastasis, suggesting their potential value as a target in cancer immunotherapy. Chlorogenic acid (CHA) has been identified potent immunomodulator that promotes the polarization of TAMs from to M1 phenotype. However, rapid clearance vivo low accumulation have compromised immunotherapeutic efficacy CHA clinical trials. In this study, mannosylated liposomes are developed for...
The aims of this study were to prepare a baicalein self-microemulsion with baicalein-phospholipid complex as the intermediate (BAPC-SMEDDS) and compare its effects those conventional (CBA-SMEDDS) on oral absorption lymphatic transport.Two SMEDDS characterized by emulsifying efficiency, droplet size, zeta potential, cloud point, dilution stability, physical in vitro release lipolysis. Different formulations 40 mg/kg orally administered Sprague-Dawley rats investigate their respective...
Proanthocyanidins (PAs) are essential secondary metabolites in grapevine, which not only determine the fruit quality but also participate plant resistance metabolism and plays a vital role regulating stress tolerance. The previous research our laboratory showed that contents of proanthocyanidins tended to increase decrease by SA treatment grape leaves. However, mechanism negative regulation proanthocyanidin biosynthesis has rarely been reported. In this study, we proposed use ' Zaoheibao'...
Agricultural productions are deeply affected by the phenological changes, especially in Shanxi Province, where Southern is main production area of winter wheat. Studying changes this region and clarifying effects varieties sowing dates on characteristics southern can be used for efficient introduction scientific sowing. We have analyzed meteorological datasets, period data, crop management data seven observation points wheat producing areas Province from 1992 to 2021. Trend analysis was...
Nitrogen (N), as a macro-element, plays vital role in plant growth and development. N deficiency affects productivity by decreasing the photosynthesis, leaf area, longevity of green leaf. The experimental design was randomized complete block with four replicates: N0 (0 kg ha−1), N90 (90 N180 (180 N210 (210 respectively, i.e., effects different application levels on photosynthetic physiology, characteristics, yield, production. findings present study underscore importance optimizing nitrogen...
Abstract An essential feature of modern high‐yielding rice varieties is the production numerous spikelets, but physiological mechanism underlying spikelet formation in these remains unclear. In this study, we explored characteristics differentiation and degeneration relevant with different panicle sizes. The regulatory effects alternate wetting moderate soil drying (AWMD) on were also measured. We determined that high number per grain yields large‐panicle primarily due to a higher...
The aim of the study was to define clinical significance circulating tumor cells (CTCs)/circulating endothelial (CTECs) and their subtypes in small cell lung cancer (SCLC) patients. CTCs/CTECs were determined using SE-iFISH technology 33 SCLC patients before initial treatment (B1), after two cycles chemotherapy (B2), at completion (B3), disease progression (B4). correlations with characteristics, progression-free survival (PFS), overall (OS) analyzed. CTCs CTECs detected 96.6% 65.5%...
Current pemetrexed/platinum chemotherapy does not produce a satisfactory therapeutic response in advanced lung cancer patients. The aim of this study was to determine whether the administration gefitinib, tyrosine kinase inhibitor (TKI), intercalated with could improve efficacy chemotherapy-naïve patients non-squamous NSCLC without subsequent gefitinib maintenance therapy. Treatment-naïve stage IIIB or IV were randomly assigned receive pemetrexed (500 mg/m2 d1) and either cisplatin (75...
Pulmonary large cell neuroendocrine carcinoma (LCNEC) and small lung cancer (SCLC) are two types of high-grade carcinomas the with poor prognosis. LCNEC has not been thoroughly studied due to its rarity, data also lacking regarding survival comparison prognosis analysis patients locally advanced or metastatic SCLC.Data LCNEC, SCLC, other NSCLC who were diagnosed from 1975 2019 extracted Surveillance, Epidemiology End Results (SEER) database estimate incidence. Those in stage III-IV being...
Programmed death ligand-1 (PD-L1) expression remains a crucial predictor in selecting patients for immunotherapy. The current study aimed to non-invasively predict PD-L1 based on chest computed tomography (CT) images advanced lung adenocarcinomas (LUAD), thus help select optimal who can potentially benefit from immunotherapy.A total of 127 with stage III and IV LUAD were enrolled into this study. Pretreatment enhanced thin-section CT available all analyzed terms both morphologic...
A variety of different lymph node (LN) staging systems have been developed to describe the status accurately. We aim compare prognostic accuracy American Joint Committee on Cancer seventh N stage relative negative number (nLN), ratio (LNR) and log odds metastatic nodes (LODDS) in rectal adenocarcinoma (RC).A total 19 167 Stage II-III cancer patients who underwent surgical resection were identified from Surveillance, Epidemiology End Results database. Akaike's Information Criterion (AIC)...
This work aimed to analyze the relative expression level of long intergenic non-protein coding ribonucleic acid 1503 (LINC01503) in cholangiocarcinoma tissues and cells, explore effects LINC01503 on cell proliferation, migration invasion.Logarithmic growth phase cells were selected transfected with Lipofectamine 2000 (si-LINC01503, si-NC). The was detected by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). proliferation observed 3-(4, 5-dimethyl-2-thiazolyl)-2,...