A5006861944- Autoimmune Bullous Skin Diseases
- Urticaria and Related Conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Dermatology and Skin Diseases
- Platelet Disorders and Treatments
- Dermatologic Treatments and Research
- Prostate Cancer Treatment and Research
- Cancer and Skin Lesions
- Monoclonal and Polyclonal Antibodies Research
- Oral and gingival health research
- Advanced Breast Cancer Therapies
- Toxin Mechanisms and Immunotoxins
- Estrogen and related hormone effects
- Oral and Maxillofacial Pathology
- Dermatological and Skeletal Disorders
- T-cell and B-cell Immunology
- Hedgehog Signaling Pathway Studies
- Infectious Diseases and Mycology
- Plant and fungal interactions
- NF-κB Signaling Pathways
- Pharmacological Effects of Natural Compounds
- Autoimmune and Inflammatory Disorders
- Ear and Head Tumors
- Celiac Disease Research and Management
- Renal function and acid-base balance
Emory University
2016-2025
Emory and Henry College
2020-2022
Emory Healthcare
2020
VA Southeast Network
2020
RELX Group (United States)
2020
Tel Aviv University
2019
Caris Life Sciences (United States)
2016-2017
University of Sarajevo
2017
Jefferson University Hospitals
2016
American Academy of Dermatology
2016
Rituximab is a therapeutic anti-CD20 monoclonal antibody widely used to treat B cell lymphoma and autoimmune diseases, such as rheumatic arthritis, systemic lupus erythematosus, blistering skin diseases (AIBD). While rituximab fully depletes peripheral blood cells, it remains unclear whether some preexisting memory pathogens or vaccines may survive depletion, especially in lymphoid tissues, if these cells can undergo homeostatic expansion during recovery from depletion. The limited data...
Hailey-Hailey disease is a severe genetic blistering of intertriginous skin locations that can lead to poor quality life and increased morbidities. Multiple therapies are available with inconsistent outcomes potentially adverse effects.To determine whether low-dose naltrexone an effective treatment for disease.This study was case series performed at dermatology outpatient clinic 3 patients recalcitrant least 4 therapies.Low-dose naltrexone, mg nightly, titrated 4.5 nightly in 2...
Pemphigus vulgaris (PV) is an autoimmune disease characterized by blistering sores on skin and mucosal membranes, caused autoantibodies primarily targeting the cellular adhesion protein, desmoglein-3 (Dsg3). To better understand how Dsg3-specific develop cause in humans, we performed a cross-sectional study of PV patients before after treatment to track relevant responses underlying pathogenesis, provide in-depth analysis two generating panel mAbs from single memory B cells (MBCs)....
Journal Article Comparison of immunological parameters in patients with pemphigus vulgaris following rituximab and IVIG therapy Get access R.J. Feldman, Feldman Center for Blistering Diseases, 70 Parker Hill Ave, Suite 208, Boston, MA 02120, U.S.A Search other works by this author on: Oxford Academic Google Scholar W.G. Christen, Christen Harvard School Public Health, Division Preventive Medicine, Brigham Women's Hospital, Medical School, MA, A.R. Ahmed Razzaque Ahmed. E‐mail:...
Dermatitis herpetiformis (DH) is an autoimmune blistering condition seen in the context of celiac disease. While typically managed by gluten-free diet and dapsone, treatment DH refractory to standard treatments not well defined.A man his 80s with controlled (with poor adherence), conventional immune-suppressing agents responded rituximab according lymphoma protocol (4 weekly infusions 375 mg/m2). Thirteen months after treatment, patient had achieved complete resolution pruritus clinical...
Abstract ETS is a family of transcriptional regulators with functions in most biological processes. Dysregulated factor function leads to altered expression multiple genes that play critical roles many the processes required for cancer progression. While Ets gene, p rostate‐ d erived E TS f actor (PDEF), expressed epithelial tissues including prostate, breast, and colon, PDEF protein has been found be reduced or lost during prostate breast The goal this study was examine biologic impact...
Abstract Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by recruitment of leucocytes into skin and release damaging enzymes, resulting in epidermal detachment blister formation. To better understand the role leukotriene B4 (LTB4) other inflammatory factors BP pathophysiology, we conducted microscopic immunohistochemical analyses preserved biopsy sections flow cytometry ELISA matched blood fluid from patients. Neutrophils predominated fluid, which also contained...