A5052708085- Animal Nutrition and Physiology
- Gut microbiota and health
- Probiotics and Fermented Foods
- Clostridium difficile and Clostridium perfringens research
- Animal Behavior and Welfare Studies
- Seaweed-derived Bioactive Compounds
- Viral gastroenteritis research and epidemiology
- Metabolomics and Mass Spectrometry Studies
- Immune Response and Inflammation
- Tuberculosis Research and Epidemiology
- Rabbits: Nutrition, Reproduction, Health
- Dementia and Cognitive Impairment Research
- Biopolymer Synthesis and Applications
- Enzyme Catalysis and Immobilization
- Chemical Synthesis and Characterization
- Mycobacterium research and diagnosis
- Ruminant Nutrition and Digestive Physiology
- Food Quality and Safety Studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Aquaculture disease management and microbiota
- Polysaccharides and Plant Cell Walls
- SARS-CoV-2 and COVID-19 Research
- NF-κB Signaling Pathways
- Ginger and Zingiberaceae research
- Escherichia coli research studies
University of California, Davis
2017-2024
Michigan State University
2023-2024
Korea Disease Control and Prevention Agency
2022-2023
Kongju National University
2007-2022
Korea National Institute of Health
2022
Pukyong National University
2022
Pusan National University Hospital
2020
Daewoo Electronics (South Korea)
2019
Chungnam National University
2011-2016
Pusan National University
2007-2015
[reaction: see text] Lipase-catalyzed transesterifications in ionic liquids proceeded with markedly enhanced enantioselectivity. It was observed that lipases were up to 25 times more enantioselective than conventional organic solvents.
There is growing evidence to support the beneficial effects of supplementing direct-fed microbials (DFM) on performance, health status, and immune responses weaned pigs. Therefore, objective this study was investigate dietary supplementation Bacillus subtilis (DSM 25841) growth diarrhea, gut permeability immunity pigs experimentally infected with a pathogenic F-18 Escherichia coli (E. coli). The F18 E. infection reduced (P < 0.05) performance intestinal villi height, whereas increased...
Previous research has shown that dietary supplementation of Bacillus spp. probiotics exerts beneficial effects on animals' growth. However, limited studies have evaluated the efficacy weaned pigs and their host gut health microbiome, systemic immunity using a disease challenge model. The objective this experiment was to investigate two strains (Bacillus subtilis DSM 32540 pumilus 32539) growth performance, diarrhea, intestinal health, experimentally infected with an enterotoxigenic...
Mycobacterium tuberculosis heparin-binding hemagglutinin (HBHA), a virulence factor involved in extrapulmonary dissemination and strong diagnostic antigen against tuberculosis, is both surface-associated secreted. The role of HBHA macrophages during M. infection, however, less well known. Here, we show that recombinant produced by smegmatis effectively induces apoptosis murine macrophages. DNA fragmentation, nuclear condensation, caspase activation, poly (ADP-ribose) polymerase cleavage were...
Mycobacterial proteins interact with host macrophages and modulate their functions cytokine gene expression profile. The protein Rv0652 is abundant in culture filtrates of Mycobacterium tuberculosis K-strain, which belongs to the Beijing family, compared levels H37Rv CDC1551 strains. induces strong antibody responses patients active tuberculosis. We investigated pro-inflammatory production induced by murine roles signalling pathways. In RAW264.7 cells bone marrow-derived macrophages,...
Individuals with cognitive impairments are evaluated using clinically validated assessment tools, which need to be administered by trained therapists. This serves as a major barrier for frequent and longitudinal monitoring of patients' impairment level. We introduce Neuro-World, set six mobile games designed challenge visuospatial short-term memory selective attention, allows one self-administer the his/her Game performance is analyzed estimate widely accepted clinical measure, mini mental...
With the emergence and rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta Omicron variants, escaping vaccine-induced immunity is a concern. Three vaccination schedules, homologous or heterologous, have been initially applied due to an insufficient supply vaccines in Korea. We investigated neutralizing activities against variants each schedule. schedules using three doses BNT162b2 (BNT) ChAdOx1 (ChAd) include ChAd-ChAd-BNT, ChAd-BNT-BNT, BNT-BNT-BNT....
The effect of tixagevimab/cilgavimab (Evusheld™; AstraZeneca, UK) should be evaluated in the context concurrent outbreak situations. For serologic investigation during BA.5 period, sera immunocompromised (IC) hosts sampled before and one month after administration those healthcare workers (HCWs) a 3rd shot COVID-19 vaccines, five months BA.1/BA.2 breakthrough infection (BI), BI were investigated. Semi-quantitative anti-spike protein antibody (Sab) test plaque reduction neutralizing (PRNT)...
Abstract The study was conducted to investigate the efficacy of a probiotic Bacillus subtilis strain on growth performance, diarrhea, systemic immunity, and intestinal health weaned pigs experimentally infected with an enterotoxigenic Escherichia coli compare B. that carbadox. Weaned (n = 48, 6.17 ± 0.36 kg body weight [BW]) were individually housed in disease containment rooms randomly allotted one four dietary treatments: negative control (NC, diet without E. challenge), positive (PC,...
Botanicals exhibit promising impacts on intestinal health, immune-regulation, and growth promotion in weaned pigs. However, these benefits may vary depending major active components the final feed additive products. Therefore, this study aimed to investigate two types of botanical blends (BB) that were comprised 0.3% capsicum oleoresin 12% garlic extracts from different sources performance, diarrhea, health piglets experimentally infected with a pathogenic Escherichia coli F18. Sixty...
Abstract The study investigated antioxidant effects of Se on resilience to diquat-induced oxidative stress in nursery pigs. Thirty-five weaned pigs were individually housed and randomly assigned one the five treatments. Pigs (1) fed a basal diet intraperitoneally injected with sterile saline (negative control), (2) diquat solution (positive control, PC), or supplemented 0·3 mg Se/kg as (3) sodium selenite (SS), (4) soyabean protein-chelated (SC) (5) selenised yeast (SY) diquat. experimental...
Abstract Crude extracts and phytochemical compounds derived from Annona muricata leaves have been demonstrated to exert neuroprotective effects. However, the effects of leaves-derived polysaccharide (ALPs) not investigated. ALP treatment was shown induce concentration-dependent antioxidant activity in HT22 cells, increase cell viability H2O2-treated cells. These were correlated with a decrease major components oxidation, including: Ca2+, ROS, malondialdehyde (MDA). Mediators intracellular...
Our previous study has reported that supplementation of oligosaccharide-based polymer enhances gut health and disease resistance pigs infected with enterotoxigenic E. coli (ETEC) F18 in a manner similar to carbadox. The objective this was investigate the impacts or antibiotic on host metabolic profiles colon microbiota weaned experimentally ETEC F18. Multivariate analysis highlighted differences serum digesta which were predominantly found between supplemented antibiotic. relative abundance...
The experiment was conducted to investigate the effects of trace amounts antibiotic on growth performance, diarrhea, systemic immunity, and intestinal health weaned pigs experimentally infected with an enterotoxigenic Escherichia coli. Weaned (n = 34, 6.88 ± 1.03 kg body weight [BW]) were individually housed in disease containment rooms randomly allotted one three dietary treatments: nursery basal diet (CON) two additional diets supplemented 0.5 or 50 mg/kg carbadox (TRA REC), respectively....
There is a great demand for antibiotic alternatives to maintain animal health and productivity. The objective of this experiment was determine the efficacy dietary supplementation blood group A6 type 1 antigen oligosaccharides-based polymer (Coligo) on growth performance, diarrhea severity, intestinal health, systemic immunity weaned pigs experimentally infected with an enterotoxigenic Escherichia coli (ETEC), when compared antibiotics. Pigs in carbadox or Coligo treatment groups had greater...
Abstract Enterotoxigenic Escherichia coli (ETEC) causes post-weaning diarrhea in piglets, significantly impacting animal welfare and production efficiency. The two primary ETEC pathotypes associated with are F4 F18. During the period, piglets may be exposed to both However, effects of coinfection by strains have not been studied. Short chain fatty acid feed additives, such as butyrate valerate, being investigated for their potential improve performance disease resistance. Therefore, this...
Effects of sucrose supplement on the pattern VFA production and microbial protein synthesis in rumen were examined sheep consuming basal diet grass silage (2.5 kg fresh wt/d) that was provided 24 equal meals each day by an automatic feeder.Four mature wethers allocated to four experimental treatments a 4×4 Latin square design with periods lasting 14 days.The (1) diet, (2) supplemented 150 g 7.0 urea, (3) 300 13 (4) 450 20 urea given as continuous intraruminal infusion for h.All infusions 2...
Individuals with permanent cognitive impairment need to be evaluated and monitored. There exists a number of clinically validated assessment tools, but they often administered by trained therapists in clinical settings. This serves as major barrier for frequent, longitudinal monitoring function. In this work, we introduce Neuro-World, collection innovative 3D mobile games, that allows one self-administer the his/her The game performance is analyzed converted into clinically-accepted measure...