A5069441170- Hypothalamic control of reproductive hormones
- Epigenetics and DNA Methylation
- Alcohol Consumption and Health Effects
- Ovarian function and disorders
- RNA Research and Splicing
- Peroxisome Proliferator-Activated Receptors
- Parkinson's Disease Mechanisms and Treatments
- Infection Control and Ventilation
- Hormonal Regulation and Hypertension
- Cancer-related molecular mechanisms research
- Animal testing and alternatives
- Growth Hormone and Insulin-like Growth Factors
- Neurological disorders and treatments
- RNA modifications and cancer
- Empathy and Medical Education
- Infection Control in Healthcare
- Viral gastroenteritis research and epidemiology
- Stress Responses and Cortisol
- Cardiac tumors and thrombi
- Hormonal and reproductive studies
- Hemostasis and retained surgical items
- Advances in Cucurbitaceae Research
- Blood transfusion and management
- Intravenous Infusion Technology and Safety
- Neurotransmitter Receptor Influence on Behavior
Kunming Medical University
2020-2025
Kunming Children's Hospital
2021-2025
Central South University
2012-2024
Xiangya Hospital Central South University
2010-2023
University of South Australia
2021
Xian Yang Central Hospital
2017
University of Alabama at Birmingham
2016
Chinese People's Liberation Army
2014
First Affiliated Hospital of Xi'an Jiaotong University
2013
Third Xiangya Hospital
2012-2013
As a cleavage enzyme of precursor TNF‐α, the high expression level ADAM17 in endothelial cells is an important factor atherosclerosis. In this study, we demonstrate that target miR‐152. We found miR‐152 could reduce TNF and inhibit cell proliferation migration by targeting human umbilical vein (HUVECs). Furthermore, pattern corresponding was opposite HUVECs under hypoxic conditions. The levels circulating AS patient sera were lower than those detected normal individuals. Our results indicate...
Dihydrotanshinone, a functional food in China, is an effective anti-cardiovascular disease substance isolated from Salvia miltiorrhiza (S. miltiorrhiza). Glioma considered to be fatal due its poor prognosis and few therapeutic options. In this study, we investigated the anticancer effects of S. extract dihydrotanshinone on human glioma SHG-44 cells, by using 3-(4, 5-dimethyl-2-thiazolyl)-2, 5-diphenyl-2H-tetrazolium bromide assay, Hoechst 33258 nuclear staining, Annexin V/propidium iodide...
Abstract Src kinase is known to regulate fibroblast migration. However, the contribution of integrin and interaction lung fibrosis has not been mechanistically investigated. Our data demonstrate that alpha v (αV) recruited leads subsequent activation in fibroblasts plated on fibrotic matrix, osteopontin. with αV required for αV-mediated activation, The study identified β5 β3 are major integrins this effect In contrast, β1, β6, β8 did have a critical role phenomenon. Importantly, inhibitor...
Biofilm-forming organisms can persist on surfaces in hospital clinical laboratories and potentially lead to nosocomial infections. Therefore, effective decontamination procedures are essential for reducing In this study, we investigated an alternative often ineffective manual cleaning methods, a pulsed xenon ultraviolet (PX-UV) light device. We evaluated PX-UV effect biofilm formation ability of pathogens also effectiveness environmental bioburden laboratories. selected identified P....
Pumpkin seed oil is widely used to treat benign prostatic hyperplasia (BPH), a common disease in elder men. However, its active components and mechanism have remained be elucidated.The objective of the present study was investigate pumpkin against BPH.Total phytosterol (TPS) isolated from hull-less (Cucurbita pepo L. var. Styriaca) analyzed by gas chromatography/mass spectrometry (GC/MS). Three phytosterols were purified preparative HPLC (high performance liquid chromatography) confirmed NMR...
The diagnostic criteria for Parkinson's disease (PD) remain complex, which is especially problematic nonmovement disorder experts. A test required to establish a diagnosis of PD with improved accuracy and reproducibility.The study aimed investigate the sensitivity specificity tests using sniffer dogs diagnose PD.A prospective, case-control was conducted in four tertiary medical centers China evaluate distinguish between 109 clinically established medicated patients PD, 654 subjects without...
In order to study the efficacy of linear-polarized near-infrared light irradiation (LPNIR) on relieving chronic pain in conjunction with nerve block (NB) or local (LB), a 3-week prospective, randomized, double-blind, controlled was conducted evaluate pre- and post-therapy intensity. Visual analogue scales (VASs) were measured all patients before 6 months after therapy visiting clinic during period August 2007 January 2008. A total 52 either shoulder periarthritis myofascial syndrome lateral...
Tumor necrosis factor-alpha (TNF-α) is a potent pro-inflammatory mediator and its expression up-regulated in chronic obstructive pulmonary disease (COPD). Tristetraprolin (TTP) implicated regulation of TNF-α expression; however, whether TTP involved cigarette smoke-induced has not been determined.TTP was examined by western blot analysis murine alveolar macrophages epithelial cells challenged without or with smoke extract (CSE). mRNA stability, the decay mRNA, were determined real-time...
Graves' disease (GD) is a common organ-specific autoimmune with the prevalence between 0.5 and 2% in women. Several lines of evidence indicate that shed A-subunit rather than full-length thyrotropin receptor (TSHR) autoantigen triggers autoimmunity leads to hyperthyroidism. We have for first time induced GD female rhesus monkeys, which exhibit greater similarity patients previous rodent models. After final immunization, monkeys injected adenovirus expressing TSHR (A-sub-Ad) showed some...
pathological features.
Non-thermal atmospheric plasma treatment and pulsed xenon ultraviolet (PX-UV) are widely used in disinfection of hospital environments. However, their effectiveness has not been evaluated against a comparator. The objective this study is to evaluate the pathogens air blood sampling rooms. Samples were taken from before after with PX-UV non-thermal plasma. We counted bacterial colonies identified types bacteria. significantly reduced counts air, median 1 zero afterwards (p = 0.03). also...
Ozone may lead to DNA breaks in airway epithelial cells. p-ATM (phosphorylated ataxia telangiectasia mutated) plays a pivotal role repair. Derivatives of NO (nitric oxide) are regulators the phosphorylation, and is increased under oxidative stress. The present study was aimed effect donor L-arg (L-arginine) on damage repair human bronchial cells exposed ozone potential mechanisms involved. HBECs (human cells) were cultured with or without (1.5 ppm, 30 min), measured comet assay agarose gel...
Urethral duplication is rare and procedures of management should be individualized according to each case's anomaly.