Hyun Lim

ORCID: 0000-0001-6581-6420
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About
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Research Areas
  • Gastric Cancer Management and Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Gastrointestinal Tumor Research and Treatment
  • Metastasis and carcinoma case studies
  • Esophageal and GI Pathology
  • Gastroesophageal reflux and treatments
  • Gastrointestinal disorders and treatments
  • Gallbladder and Bile Duct Disorders
  • Colorectal Cancer Treatments and Studies
  • Colorectal Cancer Screening and Detection
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Veterinary medicine and infectious diseases
  • Colorectal Cancer Surgical Treatments
  • Inflammatory Bowel Disease
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced Steganography and Watermarking Techniques
  • Immune Cell Function and Interaction
  • Cancer Cells and Metastasis
  • Dysphagia Assessment and Management
  • Clinical Nutrition and Gastroenterology
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Colorectal and Anal Carcinomas
  • Nanoparticle-Based Drug Delivery
  • Ear Surgery and Otitis Media

Hallym University Sacred Heart Hospital
2016-2025

Sungkyunkwan University
2023-2025

Hallym University
2015-2024

Duksung Women's University
2014-2024

Kangdong Sacred Heart Hospital
2016-2024

Hallym University Kangnam Sacred Heart Hospital
2024

University of Ulsan
2008-2023

London South Bank University
2023

Soonchunhyang University Hospital
2014-2023

Center for Digestive and Liver Diseases
2019-2021

To retrospectively assess the incremental value of an apparent diffusion coefficient (ADC) map combined with T2-weighted magnetic resonance (MR) images compared alone for prostate cancer detection by using a pathologic as reference standard.This retrospective study was approved institutional review board; informed consent waived. The included 52 patients (mean age, 65 years +/- 5 [standard deviation]; range, 48-76 years) who underwent endorectal MR imaging and step-section histologic...

10.1148/radiol.2501080207 article EN Radiology 2008-11-19

Oxidized low-density lipoproteins increase arginase activity and reciprocally decrease endothelial NO in human aortic cells. Here, we demonstrate that vascular is increased atherogenic-prone apolipoprotein E–null (ApoE −/− ) wild-type mice fed a high cholesterol diet. In ApoE mice, selective II inhibition or deletion of the gene (Arg mice) prevents high-cholesterol diet–dependent decreases production, reactive oxygen species restores function, oxidized lipoprotein–dependent increases...

10.1161/circresaha.107.169573 article EN Circulation Research 2008-02-29

Abstract Background Visual inspection, lesion detection, and differentiation between malignant benign features are key aspects of an endoscopist’s role. The use machine learning for the recognition images has been increasingly adopted in clinical practice. This study aimed to establish convolutional neural network (CNN) models automatically classify gastric neoplasms based on endoscopic images. Methods Endoscopic white-light pathologically confirmed lesions were collected classified into...

10.1055/a-0981-6133 article EN Endoscopy 2019-08-23

BACKGROUND : Deep learning models have previously been established to predict the histopathology and invasion depth of gastric lesions using endoscopic images. This study aimed establish validate a deep learning-based clinical decision support system (CDSS) for automated detection classification (diagnosis prediction) neoplasms in real-time endoscopy. METHODS The same 5017 images that were employed previous used training data. primary outcomes were: (i) lesion rate model, (ii) accuracy...

10.1055/a-2031-0691 article EN Endoscopy 2023-02-08

Triple-negative breast cancer (TNBC) is associated with a poor prognosis and metastatic growth. TNBC cells frequently undergo macroautophagy/autophagy, contributing to tumor progression chemotherapeutic resistance. ANXA2 (annexin A2), potential therapeutic target for TNBC, has been reported stimulate autophagy. In this study, we investigated the role of in autophagic processes cells. patients exhibited high levels ANXA2, which correlated outcomes. increased LC3B-II following bafilomycin A1...

10.1080/15548627.2024.2305063 article EN Autophagy 2024-01-30

The purpose of this study is to evaluate the associations between gastroesophageal reflux disease (GERD) and depression using a national sample cohort Korean population. Data were collected from individuals ≥20 years old in National Health Insurance Service-National Sample Cohort 2002 2013. We designed two different nested case-control studies. In I, 60,957 participants with matched at 1:4 ratio 243,828 controls, their previous histories GERD analyzed. II, 133,089 1:2 266,178 Crude adjusted...

10.1038/s41598-018-29629-7 article EN cc-by Scientific Reports 2018-07-31

Abstract Background The Korean College of Helicobacter and Upper Gastrointestinal Research has studied pylori (H. pylori) prevalence since 1998 found a dynamic change in its Korea. aim this study was to determine the recent H. rate compare it with that previous studies according socioeconomic variables. Methods We planned enroll 4920 asymptomatic adults from 21 centers population distribution seven geographic areas (Seoul, Gyeonggi, Gangwon, Chungcheong, Kyungsang, Cholla, Jeju). centrally...

10.1111/hel.12463 article EN cc-by Helicobacter 2018-01-18

Classification of colorectal neoplasms during colonoscopic examination is important to avoid unnecessary endoscopic biopsy or resection. This study aimed develop and validate deep learning models that automatically classify lesions histologically on white-light colonoscopy images.

10.3390/jcm9051593 article EN Journal of Clinical Medicine 2020-05-24

Ga Hee Kim, Ji Yong Ahn, Hwoon-Yong Jung, Young Soo Park, Min-Ju Kee Don Choi, Jeong Hoon Lee, Kwi-Sook Do Hyun Lim, Ho June Song, Gin Hyug and Jin-Ho Kim. Gut Liver 2015;9:615-22. https://doi.org/10.5009/gnl14032

10.5009/gnl14032 article EN cc-by-nc Gut and Liver 2014-12-04
LISA Consortium Waveform Working Group Niayesh Afshordi Sarp Akçay Pau Amaro‐Seoane Andrea Antonelli and 95 more Josu C. Aurrekoetxea Leor Barack Enrico Barausse Robert Benkel Laura Bernard Sebastiano Bernuzzi Emanuele Berti Matteo Bonetti Béatrice Bonga Gabriele Bozzola Richard Brito Alessandra Buonanno Alejandro Cárdenas-Avendaño Marc Casals David Chernoff Alvin J. K. Chua Katy Clough M. Colleoni Mekhi Dhesi Adrien Druart Leanne Durkan Guillaume Faye D. L. Ferguson Scott E. Field W. Gabella J. García-Bellido Miguel Gracia-Linares Davide Gerosa Stephen Green M. Haney Mark Hannam Anna Heffernan Tanja Hinderer Thomas Helfer Scott A. Hughes S. Husa Soichiro Isoyama Michael L. Katz Chris Kavanagh Gaurav Khanna Larry Kidder Valeriya Korol Lorenzo Küchler Pablo Laguna François Larrouturou Alexandre Le Tiec Benjamin Leather Eugene A. Lim Hyun Lim T. B. Littenberg Oliver Long Carlos O. Lousto Geoffrey Lovelace Georgios Lukes-Gerakopoulos Philip Lynch Rodrigo Panosso Macedo C. Markakis Elisa Maggio Ilya Mandel Andrea Maselli Josh Mathews Pierre Mourier David Neilsen Alessandro Nagar David A. Nichols Jan Novák Maria Okounkova R. O’Shaughnessy Naritaka Oshita Conor O’Toole Zhen Pan Paolo Pani George Pappas Vasileios Paschalidis Harald Pfeiffer Lorenzo Pompili Adam Pound G. Pratten Hannes R. Rüter Milton Ruiz Zeyd Sam Laura Sberna Stuart L. Shapiro Deirdre Shoemaker Carlos F. Sopuerta Andrew Spiers Hari Sundar Nicola Tamanini Jonathan E. Thompson Alexandre Toubiana Antonios Tsokaros Samuel D. Upton Maarten van de Meent Daniele Vernieri Jeremy M. Wachter

LISA, the Laser Interferometer Space Antenna, will usher in a new era gravitational-wave astronomy. As first anticipated space-based detector, it expand our view to millihertz sky, where spectacular variety of interesting sources abound: from millions ultra-compact binaries Galaxy, mergers massive black holes at cosmological distances; beginnings inspirals that venture into ground-based detectors' death spiral compact objects holes, and many between. Central realising LISA's discovery...

10.48550/arxiv.2311.01300 preprint EN cc-by arXiv (Cornell University) 2023-01-01

Gastroesophageal reflux disease (GERD) is a chronic and recurrent condition requiring constant dietary management medication. This study evaluated the efficacy safety of HIP1601, dual delayed-release formulation esomeprazole, in patients with GERD clinical setting. prospective, multicenter, observational was conducted at 309 medical institutions Korea between June 2021 March 2023. HIP1601 administered daily doses 40 mg or 20 to 5,407 treatment prevention erosive esophagitis. The primary...

10.4166/kjg.2024.124 article EN cc-by-nc Korean Journal of Gastroenterology 2025-01-24

Hyun Lim, Ju Yup Lee, Yong Hwan Kwon, Hee Seok Moon, Jong Kyu Park, Ki Bae Kim, Sang Wook Young Hoon Youn, Gyun Gwang Ha Ji Won Jae-Young Jang, Kye Sook Joong Goo Hyun-Soo Su Jin Hong, Kwang Jae Suck Chei Choi, Jeong Seop Nayoung Jong-Jae Yirang Sung Hwoon-Yong Jung. Gut and Liver -0001;0:. https://doi.org/10.5009/gnl240390

10.5009/gnl240390 article TL cc-by-nc Gut and Liver 2025-02-14

A customized screening program for gastric cancer would optimize the benefits of endoscopy. This study investigated risk factors detected during and affecting clinical outcomes.From April 2000 to December 2010, subjects who underwent endoscopy at Asan Medical Center were included. To investigate factors, age- sex-matched control group was selected. The outcomes identified (screening group) compared with age, sex, date diagnosis-matched diagnosed in outpatient clinic (outpatient group).Of 109...

10.1111/jgh.12387 article EN Journal of Gastroenterology and Hepatology 2013-10-12

Aim To compare the efficacy and safety between modified quadruple- bismuth-containing quadruple therapy as first-line eradication regimen for Helicobacter pylori infection.Methods This study was a multicenter, randomized-controlled, non-inferiority trial. Subjects endoscopically diagnosed with H. infection were randomly allocated to receive (rabeprazole 20 mg bid, amoxicillin 1 g metronidazole 500 tid, bismuth subcitrate 300 qid [elemental 480 mg]; PAMB) or qid, tetracycline qid; PBMT) 14...

10.1080/19490976.2020.1754118 article EN cc-by-nc Gut Microbes 2020-05-02
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