A5080065732- Vector-borne infectious diseases
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Study of Mite Species
- Pregnancy and preeclampsia studies
- Viral Infections and Vectors
- Acute Myeloid Leukemia Research
- Cancer-related molecular mechanisms research
- Reproductive System and Pregnancy
- MicroRNA in disease regulation
- Circular RNAs in diseases
- RNA modifications and cancer
- Bird parasitology and diseases
- Birth, Development, and Health
- Hemoglobinopathies and Related Disorders
- Animal Ecology and Behavior Studies
- Mosquito-borne diseases and control
- Tuberculosis Research and Epidemiology
- Cancer, Hypoxia, and Metabolism
- Mycobacterium research and diagnosis
- Health disparities and outcomes
- Bone Tissue Engineering Materials
- Immune cells in cancer
- Preterm Birth and Chorioamnionitis
- Parasitic Infections and Diagnostics
- Periodontal Regeneration and Treatments
Dali University
2014-2025
Sichuan University
2025
West China Hospital of Sichuan University
2025
Third Affiliated Hospital of Sun Yat-sen University
2024
Sun Yat-sen University
2024
Renji Hospital
2024
Shanghai Jiao Tong University
2024
Jiangsu Cancer Hospital
2021-2024
Nanjing Medical University
2011-2024
China Three Gorges University
2022-2024
Children's health and behaviour are essential for their development it is important to obtain abundant accurate information understand young people's behaviour. The Health Behaviour in School-aged Children (HBSC) study among the first large-scale international surveys on adolescent through self-report questionnaires. So far, more than 40 countries Europe North America have been involved HBSC study. purpose of this assess test-retest reliability selected items Chinese version survey...
Abstract Chemoresistance and relapse are the leading cause of AML-related deaths. Utilizing single-cell RNA sequencing (scRNA-seq), we dissected cellular states bone marrow samples from primary refractory or short-term relapsed AML patients defined transcriptional intratumoral heterogeneity. We found that compared to proliferating stem/progenitor-like cells (PSPs), a subpopulation quiescent stem-like (QSCs) were involved in chemoresistance poor outcomes AML. By performing longitudinal...
We aimed to explore the expression level and biological function of lncRNA PVT1 in human trophoblast cells.The levels cancer cell lines, HTR8/SVneo cell, HUVEC maternal placenta GDM patients, PE patients normal pregnancy were detected by qRT-PCR. The culture, transfection, CCK-8 assay, flow cytometry, wound scratch assay transwell carried out determine effects silencing overexpression on line. Nuclear chromatin RNA fraction RNA-sequencing, western blot qRT-PCR conducted preliminarily...
Cutaneous T cell lymphoma (CTCL) is characterized by the accumulation of malignant cells in skin. However, advanced CTCL pathophysiology remains elusive and therapeutic options are limited due to high intratumoral heterogeneity complicated tumor microenvironment (TME). By comparing single-cell RNA-seq (scRNA-seq) data from patients healthy controls (HCs), we showed that had a higher enrichment T/NK myeloid cells. Subpopulations (CXCR3
Various studies have demonstrated the associations between socioeconomic status (SES) and health behaviour among adolescents. However, few compared difference in adolescent smoking countries with different stage of smoking. The purpose this study was to examine compare relationship Beijing, China Finland through Health Behaviour School-aged Children (HBSC) study. data used were derived from Chinese HBSC linked project survey 2008 Beijing Finnish 2006. final sample included 2005 1685...
Leptotrombidium rupestre, a chigger species, is potential vector of scrub typhus. Based on field surveys in southwest China between 2001 and 2022, this paper retrospectively reports the distribution host selection L. rupestre region for first time. A total 4675 were identified from 28 species rodents other sympatric small mammal hosts 23 out 114 survey sites, it was mainly distributed higher latitudes (31-33° N) altitudes (3000-3500 m), especially western Sichuan, an important focus Among...
Abstract Introduction: Pulmonary function tests (PFTs) are the gold standard for diagnosing of Chronic obstructive pulmonary disease (COPD). Given its limitation in some scenarios, it is imperative to develop new high-throughput screening methods biomarkers COPD. This study aims explore feasibility novel diagnostic based on salivary metabolomics limited availability PFTs and difficulties implementation at primary care facilities.

Methods: Participants were recruited from...
The Asian house rat (Rattus tanezumi) is an important infectious source and reservoir host for many zoonotic diseases, its associated mites (chigger gamasid mites) can act as vectors these diseases. present study aimed to elucidate the infestation patterns related ecology of on body surface R. tanezumi in southwest China explore relevant risk models. Field surveys taxonomic identification were conducted across five provincial regions between 2001 2022. constituent ratio (Cr ), prevalence (Pm...
Abstract Background Infertile women often face stigmatization worldwide. This study aimed to investigate the stigma against infertile in China and analyze its influencing factors. Methods Of 270 who were randomly selected from patients receiving adjuvant fertility treatment Zhejiang Province, China, 254 successfully completed general information questionnaire, disease Chinese version of infertility scale (ISS). The ISS contained 27 positively worded items, each which was graded on a 5-point...
Abstract Diverse post-translational modifications have been shown to play important roles in regulating protein function eukaryotes. By contrast, the of bacteria are not so well understood, particularly as they relate pathogenesis. Here, we demonstrate modification by covalent addition lactate lysine residues (lactylation) human pathogen Staphylococcus aureus . Lactylation is dependent on concentration and specifically affects alpha-toxin, which a single lactylated required for full activity...
To measure the expression levels of sputum and serum microRNA-144 (miR-144) before after treatment patients with tuberculosis (TB).Details cases a total 124 TB were collected at Qilu Hospital Shandong University between April 2014 2015. Fifty-three these had positive for bacteria cavity on imaging (group A), 20 negative B), 51 no C). One hundred seventeen healthy people who attended hospital physical examination recruited as controls. Quantitative real-time PCR (qRT-PCR) was used to miR-144...
MicroRNAs (miRNAs) are a group of non-protein‑coding, short single-stranded RNAs, which considered as promising molecular markers and therapeutic targets in several cancers. The present study explored the expression patterns functional roles miR‑202 non‑small cell lung cancer (NSCLC). levels were determined NSCLC tissues lines using reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR). impact overexpression on viability, migration invasion evaluated Cell Counting Kit‑8...
Chigger mites are the common ectoparasites of rodents and exclusive vector scrub typhus. The Southeast Asian house rat (Rattus brunneusculus) is an important reservoir host infectious source some zoonoses including From April 2016 to March 2017, a 12-month consecutive investigation was made at Jingha village in southern Yunnan China, which focus infestation seasonal fluctuation chigger on R. brunneusculus were studied based investigation. 2,053 captured brunneusculus, total 99,221 chiggers...
Abstract Substrate topographical features induce osteogenic differentiation of bone marrow stem cells (BMSCs), but the underlying mechanisms are unclear. As microRNAs (miRNAs) play key roles in osteogenesis and regeneration, it would be meaningful to elucidate miRNAs intracellular signaling cascade cue‐induced differentiation. In this study, miRNA expression profile feature‐induced group is different from that chemical‐factors‐induced group. miR‐193a‐3p sensitive substrate its downregulation...
The expression of vascular endothelial growth factor (VEGF) and soluble fms-like tyrosine kinase-1 (sFLT-1) in the serum patients with pregnancy induced hypertension (PIH) syndrome its effects on foetus was explored. A total 105 cases PIH pregnant women admitted to First People's Hospital Changzhou from March 2015 February 2018 were divided into 3 groups according severity patient's condition. Group (n=35) complicating pregnancy, group B (n=46) mild preeclampsia C (n=24) severe preeclampsia....
Abstract Background Aggressive B-cell non-Hodgkin’s lymphoma (B-NHL) patients often develop drug resistance and tumor recurrence after conventional immunochemotherapy, for which new treatments are needed. Methods We investigated the antitumor effects of CBL0137. In vitro, cell proliferation was assessed by CCK-8 colony formation assay. Flow cytometry performed to analyze cycle progression, apoptosis, mitochondrial depolarization, reactive oxygen species (ROS) production. Autophagy detected...