- Inflammatory Bowel Disease
- Microscopic Colitis
- Infant Nutrition and Health
- Pediatric Hepatobiliary Diseases and Treatments
- Eosinophilic Esophagitis
- Clinical Nutrition and Gastroenterology
- Immunodeficiency and Autoimmune Disorders
- Probiotics and Fermented Foods
- Intestinal Malrotation and Obstruction Disorders
- Child Nutrition and Feeding Issues
- Gut microbiota and health
- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Gallbladder and Bile Duct Disorders
- Liver Disease Diagnosis and Treatment
- Infant Health and Development
- Adolescent and Pediatric Healthcare
- Celiac Disease Research and Management
- Digestive system and related health
- Breastfeeding Practices and Influences
- Liver Disease and Transplantation
- Childhood Cancer Survivors' Quality of Life
- Autoimmune and Inflammatory Disorders
- Food Allergy and Anaphylaxis Research
- Gastrointestinal disorders and treatments
University Children's Hospital Zurich
2015-2024
Deutsche Akademie für Kinder- und Jugendmedizin
2023
University of Zurich
1996-2023
Swiss Paediatric Oncology Group
2023
University Hospital of Lausanne
2022
University of Lausanne
2022
University Hospital of Zurich
1999-2021
GTx (United States)
2014-2018
Swiss HIV Cohort Study
2018
Uniwersytecki Szpital Dziecięcy
1996-2017
Children and adolescents with Crohn's disease (CD) present often a more complicated course compared to adult patients. In addition, the potential impact of CD on growth, pubertal emotional development patients underlines need for specific management strategy pediatric-onset CD. To develop first evidenced based consensus driven guidelines an expert panel 33 IBD specialists was formed after open call within European Colitis Organisation Society Pediatric Gastroenterolog, Hepatology Nutrition....
ABSTRACT This medical position article by the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition summarises current status of breast‐feeding practice, present knowledge on composition human milk, advisable duration exclusive partial breast‐feeding, growth breast‐fed infant, health benefits associated with nutritional supplementation infants, contraindications to breast‐feeding. emphasises important role paediatricians in implementation policies devised promote The...
This study determined the location and tissue density of cells immunoreactive for tumour necrosis factor alpha (TNF alpha) in intestinal specimens from 24 patients with chronic inflammatory bowel disease (15 Crohn9s disease, nine ulcerative colitis) 11 controls. There was significantly increased TNF lamina propria both colitis specimens, although distribution these differed two conditions. In most immunoreactivity seen subepithelial macrophages, comparatively less deep propria, while were...
Summary Breast milk has recently been recognized as source of commensal and potential probiotic bacteria. The present study investigated whether viable strains gut‐associated obligate anaerobes are shared between the maternal neonatal gut ecosystem via breastfeeding. Maternal faeces, breast corresponding faeces collected from seven mothers‐neonate pairs at three sampling points were analyzed by culture‐independent (pyrosequencing) culture‐dependent methods (16 S rRNA gene sequencing, pulsed...
The contemporary management of ambulatory ulcerative colitis (UC) continues to be challenging with ∼20% children needing a colectomy within childhood years. We thus aimed standardize daily treatment pediatric UC and inflammatory bowel diseases (IBD)-unclassified through detailed recommendations practice points.These guidelines are joint effort the European Crohn's Colitis Organization (ECCO) Paediatric IBD Porto group Society Gastroenterology, Hepatology Nutrition (ESPGHAN). An extensive...
ABSTRACT Background and Aims: Pediatric ulcerative colitis (UC) shares many features with adult‐onset disease but there are some unique considerations; therefore, therapeutic approaches have to be adapted these particular needs. We aimed formulate guidelines for managing UC in children based on a systematic review (SR) of the literature robust consensus process. The present article is product joint effort European Crohn's Colitis Organization (ECCO) Society Paediatric Gastroenterology,...
Initial neonatal gut colonisation is a crucial stage for developing healthy physiology, beneficially influenced by breast-feeding. Breast milk has been shown not only to provide nutrients and bioactive/immunological compounds, but also commensal bacteria, including gut-associated anaerobic Bifidobacterium spp. The aim of the present study was investigate bacterial diversity in breast milk, with emphasis on identifying obligate anaerobes. collected from seven mothers at three sampling points...
Background: Vitamin D and calcium deficiencies are common worldwide, causing nutritional rickets osteomalacia, which have a major impact on health, growth, development of infants, children, adolescents; the consequences can be lethal or last into adulthood. The goals this evidence-based consensus document to provide health care professionals with guidance for prevention, diagnosis, management policy makers framework work toward its eradication. Evidence: A systematic literature search...
The establishment of a pioneer gut microbiota is increasingly recognized as crucial stage in neonatal development influencing health throughout life. While current knowledge mainly based on either culture or molecular analysis feces, we opted for comprehensive approach complementing with state-of-the-art methods. bacterial composition feces from seven healthy vaginally-delivered, breast-fed neonates was analyzed at days 4-6, 9-14 and 25-30 postnatal, using culture, 16S rRNA gene sequencing...
ABSTRACT Enteral nutrition support (ENS) involves both the delivery of nutrients via feeding tubes and provision specialised oral nutritional supplements. ENS is indicated in a patient with at least partially functioning digestive tract when intake inadequate or normal food inappropriate to meet patients' needs. The aim this comment by Committee on Nutrition European Society for Pediatric Gastroenterology, Hepatology, provide clinical practice guide ENS, based available evidence expertise...
The diagnosis of inflammatory bowel disease (IBD), comprising Crohn's (CD) and ulcerative colitis (UC), continues to present difficulties due unspecific symptoms limited test accuracies. We aimed determine the diagnostic delay (time from first IBD diagnosis) identify associated risk factors. A total 1591 patients (932 CD, 625 UC, 34 indeterminate colitis) Swiss cohort study (SIBDCS) were evaluated. SIBDCS collects data on a large sample hospitals private practice across Switzerland through...