A5049173147- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Food Allergy and Anaphylaxis Research
- Immunodeficiency and Autoimmune Disorders
- Systemic Lupus Erythematosus Research
- Respiratory Support and Mechanisms
- Autoimmune and Inflammatory Disorders Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Inhalation and Respiratory Drug Delivery
- Inflammasome and immune disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Immune Cell Function and Interaction
- Blood disorders and treatments
- Neonatal Respiratory Health Research
- Pediatric health and respiratory diseases
- Natural Antidiabetic Agents Studies
- Cell Adhesion Molecules Research
- Peripheral Neuropathies and Disorders
- COVID-19 and healthcare impacts
- Chronic Lymphocytic Leukemia Research
- Phytochemicals and Antioxidant Activities
- Liver Disease and Transplantation
- Respiratory and Cough-Related Research
- Phytochemistry and Biological Activities
- Contact Dermatitis and Allergies
Ain Shams University
2013-2024
Ain Shams University Hospital
2013-2024
Benha University
2024
Cairo University
2017-2024
Tanta University
2022-2023
Children's Hospital
2021-2022
Zagazig University
1994-2022
ENT and Allergy
2020-2022
Virginia Commonwealth University
2019
National Research Centre
1994-1995
Abstract Background The interplay between COVID‐19 pandemic and asthma in children is still unclear. We evaluated the impact of on childhood outcomes. Methods PeARL multinational cohort included 1,054 with 505 non‐asthmatic aged 4 18 years from 25 pediatric departments, 15 countries globally. compared frequency acute respiratory febrile presentations during first wave groups data available previous year. In asthma, we also current historical disease control. Results During pandemic,...
Autoimmunity to brain could play an etiopathogenic role in a subgroup of autistic patients. The frequency serum anti-myelin-associated glycoprotein antibodies, as index for autoimmunity brain, and their relation family history were investigated 32 healthy matched children. Autistic children had significantly higher antibodies than (2100 [1995] 1138 [87.5] Buhlmann titre unit, P < .001). Anti-myelin-associated positivity was elicited 62.5% Family (50%) controls (9.4%). levels with those...
BackgroundAllergies have long been observed in Inborn Errors of Immunity (IEI) and might even be the first presentation resulting delayed diagnosis or misdiagnosis some cases. However, data on prevalence allergic diseases among IEI patients are limited contradictory.ObjectiveTo provide a worldwide view diseases, across broad spectrum IEI, their impact timely IEI.MethodsThis is study, conceived by World Allergy Organization (WAO) Committee. A questionnaire was developed pilot-tested sent via...
Cardiovascular autonomic neuropathy (CAN) in patients with rheumatic diseases may result sudden death, possibly from arrhythmia and myocardial infarction due to its frequent association microvascular disease. Autonomic dysfunction contribute initiation perpetuation of diseases. Thus, we aimed assess cardiovascular function lupus juvenile idiopathic arthritis (JIA) patients.Assessment was done 20 JIA patients, aged 8-16 years, by five non-invasive tests (AFTs) serum levels neuropeptide Y...
Importance Childhood asthma control largely depends on rigorous and regular monitoring. Although various clinical parameters, biomarkers, patient-reported outcomes are helpful for monitoring purposes, there is no consensus the minimum and/or optimal set of parameters their relative priority. Objective To assess actual perceived childhood practices used globally. Design, Setting, Participants This international, multistakeholder survey study surveyed health care professionals academics with a...
Objectives: We aimed to investigate alpha beta double negative (αβ DN) T-cell percentages in juvenile systemic lupus erythematosus (JSLE) and their relation disease activity organ involvement. Methods: This prospective study was carried out over a period of 12 months included 21 JSLE patients 20 healthy matched controls. SLE index 2000 (SLEDAI-2K) scores were recorded addition αβ DN measurement at enrollment after remission. Results: Enrolled (n = 21) females with age range 10–17 years....
Purpose: To evaluate the frequency of banana sensitization and allergy among a group atopic Egyptian children in relation to parental/self reports.Methods: This is case-control study included 2 groups allergic with without history allergy, each 40 patients.They were subjected skin prick test (SPT) using commercial allergen extract prick-prick (PPT) raw banana, addition measuring serum banana-specific IgE.Oral challenge was performed suspected cases.Results: Banana diagnosed 3 (7.5%)patients...
ABSTRACT Importance Importance: The interplay between COVID-19 pandemic and asthma in children is still unclear. Objective We evaluated the impact of on childhood outcomes. Design PeARL multinational cohort included with non-asthmatic controls recruited during compared current disease activity data available from previous year. Setting Pediatric outpatient clinics. Participants study 1,054 505 controls, aged 4-18 years, 25 pediatric departments, 15 countries globally. Exposures first wave,...
The β2 integrins are expressed exclusively on leukocytes and participate in many immune inflammatory processes. This subfamily comprises four heterodimeric glycoproteins with a common β-subunit, designated (CD18). Spontaneous mutations of the CD18 gene result leukocyte adhesion deficiency type I (LAD-I). Low level expression has also been implicated pathogenesis psoriasis. We here describe child recurrent skin infections without pus formation, persistent gingivitis periodontitis. His blood...
Early recognition of an anaphylaxis event is crucial for instituting lifesaving management. We sought to explore knowledge and practice towards in a sample physicians from ten Egyptian governorates.An eighteen question-based questionnaire was developed by expert allergists evaluate the anaphylaxis, based on World Allergy Organization guidelines assessment management anaphylaxis. The questionnaires were distributed, answered forms collected via emails, data tabulated, analysed.In this...
The tumor suppressor protein p53 plays an important role in cell cycle regulation. One of the major features rheumatic diseases is abnormal proliferation lymphocytes. expression peripheral blood mononuclear cells (by flowcytometry) and serum anti‐p53 antibodies ELISA) were therefore measured 18 children adolescents with juvenile rheumatoid arthritis (JRA) 17 systemic lupus erythematosus (SLE) comparison to 20 healthy controls, determine their role. patients was insignificantly higher than...
The air dried leaves of Laurus nobilis cultivated in Egypt were extracted by petroleum ether followed methylene chloride then ethyl acetate and finally methanol.The preliminary cytotoxic screening these extracts against Hep-G2 using vinblastine sulfate (IC50= 2.93 μg/ml) as standard showed that ether, exhibited strong activity 10.6, 5.96 3.80 μg/ml, respectively) while the methanolic extract moderate 23.2 μg/ml).Bio-guided chromatographic isolation L. resulted five compounds identified...
Two polymethoxyflavones,5-O-demethylnobiletin and 7,4'-dihydroxy-5,6,8,3'-tetramethoxyflavones were isolated from the chloroform extracts of fresh yellow-orange berries Solanum abutiloides. The two compounds are reported for first time in genus Solantum. light petroleum fraction, gave branched aliphatic alcohol, α-amyrin, lupeol, phytosterol stigmasterol glucoside. Identification these was established on basis 1'H-NMR, MS, UV, IR comparison with authentic samples. GLC analysis fatty acid...