A5016064405- Immunodeficiency and Autoimmune Disorders
- Respiratory viral infections research
- Influenza Virus Research Studies
- Blood disorders and treatments
- Immune Cell Function and Interaction
- Viral Infections and Outbreaks Research
- Pneumonia and Respiratory Infections
- Parvovirus B19 Infection Studies
- T-cell and B-cell Immunology
- Infectious Encephalopathies and Encephalitis
- Cytomegalovirus and herpesvirus research
- Helicobacter pylori-related gastroenterology studies
- Streptococcal Infections and Treatments
- Antibiotic Resistance in Bacteria
- Inflammasome and immune disorders
- Sepsis Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Child Nutrition and Water Access
- Immune Response and Inflammation
- Child Nutrition and Feeding Issues
- Neonatal Respiratory Health Research
- Nosocomial Infections in ICU
- Kawasaki Disease and Coronary Complications
- Infections and bacterial resistance
- Vaccine Coverage and Hesitancy
American University of Beirut
2012-2025
Office of Adolescent Health
2024
American University of Beirut Medical Center
2012-2023
Stanford University
2008-2009
Background: Urinary tract infections (UTIs) are among the most common in pediatric population. Over last two decades, antibiotic resistance is increasing significantly as extended spectrum beta lactamase (ESBL) producing organisms emerging. The aim of this study to provide a comprehensive view epidemiologic characteristics UTIs hospitalized children, examine risk factors caused by ESBL-producing organisms, and determine patterns isolated over 10 years. Methods: Retrospective chart review was...
Respiratory syncytial virus (RSV) is a leading cause of pediatric death, with >99% mortality occurring in low- and lower middle-income countries. At least half RSV-related deaths are estimated to occur the community, but clinical characteristics this group children remain poorly characterized.The RSV Global Online Mortality Database (RSV GOLD), global registry under-5 who have died illness, describes dying through data sharing. GOLD acts as collaborative platform for deaths, including...
Introduction Studies on the clinical presentation of celiac disease and its impact growth children in Lebanon are limited. The aim this 10-year-retrospective study was to describe common presentations, diagnostic modalities, effect gluten-free- diet (GFD) adolescents with disease. Methods This a retrospective chart review subjects aged 6 months 18 years who visited Pediatric Gastroenterology clinic at American University Beirut Medical Center (AUBMC) between January 1, 2013, June 30, 2023,...
In a mumps outbreak in the United States, many infected individuals were adults who had received 2 doses of vaccine. The persistence cellular immunity to vaccine has not been defined.This was an observational, nonrandomized cohort study evaluating cell-mediated and humoral 10 vaccinated naturally immune adults. Mumps-specific T cell activation interferon (IFN)-gamma production measured using lymphoproliferative flow cytometry assays, immunoglobulin (Ig) G enzyme-linked immunosorbent assay.T...
Abstract Human nude SCID is a rare autosomal recessive inborn error of immunity (IEI) characterized by congenital athymia, alopecia, and nail dystrophy. Few cases have been reported to date. However, the recent introduction newborn screening for IEIs high-throughput sequencing has led identification novel atypical cases. Moreover, immunological alterations recently described in patients carrying heterozygous mutations. The aim this paper describe extended phenotype associated with FOXN1...
The susceptibility of infants to infections is well defined clinically, and immunologic abnormalities have been described. Immune maturation complex, however, the interval during which changes occur childhood has not identified.To assess age-related differences in CD4(+) T cell responses, we evaluated frequency cells that produced interferon (IFN) gamma response staphylococcal enterotoxin B (SEB) stimulation 382 healthy children (2 months 11 years age) 66 adults. Flow cytometry was used...
Reports of multisystem inflammatory syndrome in children (MIS-C), following severe acute respiratory coronavirus 2 (SARS-CoV-2) infection, have been increasing worldwide, with an incidence varying significantly across studies based on the definition used for diagnosis. At our tertiary medical center Lebanon, we encountered several cases that presented a diagnostic challenge because they mimicked MIS-C but did not meet US Centers Disease Control and Prevention (CDC) definition. We decided to...
Introduction: Device-associated healthcare-associated infections (DA-HAIs) are the principal threat to patient safety in intensive care units (ICUs). The primary objective of this study was identify most common DA-HAIs pediatric unit (PICU) at American University Beirut Medical Center (AUBMC). Length stay (LOS) and mortality, antimicrobial resistance patterns, suitability empiric antibiotic choices for according local patterns were also studied. Methodology: This a retrospective that...
Background Pediatric oncology patients with fever, even when not neutropenic, are known to be at an increased risk of bloodstream infections. However, there no standard guidelines for management fever in non-neutropenic patients, resulting variability practice across institutions. Procedure We retrospectively analyzed the clinical characteristics, management, and outcome all febrile episodes pediatric a single institution over two-year period 2011–2012, identify predictors assessed efficacy...
Abstract Background Influenza is a major cause of morbidity and mortality worldwide. Following the 2009 pandemic, there was widened interest in studying influenza burden all regions. However, since data from World Health Organization (WHO) Middle East North Africa (MENA) region remain limited, we aimed to contribute understanding Lebanon. Methods A retrospective chart review extending over period 8 seasons Jan 1st, 2008 till June 30th, 2016 at tertiary care center Beirut performed. All cases...
Congenital syphilis remains a significant public health problem nowadays. We describe the presentation of an infant with delayed diagnosis congenital syphilis, negative initial non-treponemal test. Our aim is to shed light on incidence missed prevention, importance awareness, maternal screening, and early diagnosis.
Bronchiolitis and more specifically respiratory syncytial virus (RSV) bronchiolitis is a leading cause of global childhood morbidity mortality. Despite the previous identification possible risk factors associated with severity bronchiolitis, data from Lebanon remains limited. We described burden hospitalizations in children under 5 years age tertiary care center October 2004 to 2014 identified severe bronchiolitis. This was retrospective cohort study conducted at American University Beirut...
Influenza virus infection is an important cause of under-five mortality. Maternal vaccination protects children younger than 3 months age from influenza infection. However, it unknown to what extent paediatric influenza-related mortality may be prevented by a maternal vaccine since global age-stratified data are lacking.We invited clinicians and researchers share clinical demographic characteristics 5 years who died with laboratory-confirmed between January 1, 1995 March 31, 2020. We...